Disease relevance of Origanum

• Because of their longstanding safety record, origanum and/or monolaurin, alone or combined with antibiotics, might prove useful in the prevention and treatment of severe bacterial infections, especially those that are difficult to treat and/or are antibiotic resistant [1].

Psychiatry related information on Origanum

• The preferred essential oils, chosen by the mothers for their child, from 36 commonly used aromatherapy oils, were: sweet marjoram, frankinsence, German chamomile, myrrh, thyme, benzoin, spike lavender and Litsea cubeba [2].

High impact information on Origanum

• Seed oils of Origanum onites L. from the Antalya and Mugla regions and O. vulgare L. from the Kirklareli region of Turkey were extracted with hexane in a Soxhlet apparatus [3].
• Volatile yield is highly variable among individual plants and concentration also presents a high variation for most Origanum volatile compounds, linalool being the main component in most samples [4].
• A soluble enzyme preparation from the leaves of sweet marjoram (Majorana hortensis Moench) catalyzes the divalent cation-dependent cyclization of [1-3H]geranyl pyrophosphate to the bicyclic monoterpene alcohols (+)-[6-3H]cis- and (+)-[6-3H]-transsabinene hydrate, providing labeling patterns consistent with current mechanistic considerations [5].
• Preliminary study of phenolic glycosides from Origanum majorana; quantitative estimation of arbutin; cytotoxic activity of hydroquinone [6].
• Evaluation of aldose reductase inhibition and docking studies of some secondary metabolites, isolated from Origanum vulgare L. ssp. hirtum [7].

Biological context of Origanum

• Therefore, these results indicate that micromolar Abeta-induced oxidative cell death is reduced by ursolic acid from Origanum majorana L [8].

Anatomical context of Origanum

• We have investigated the effects of carvacrol obtained by fractional distillation of Origanum onites L. essential oil, on DNA synthesis of N-ras transformed myoblast cells, CO25 [9].
• The effect of ursolic acid from Origanum majorana L. on Abeta-induced neurotoxicity was investigated using PC12 cells [8].

Associations of Origanum with chemical compounds

• Residues detected in fresh marjoram, mint, and chamomile were 0.18, 0.23, and 0.083 mg/kg, respectively [10].
• Similar to origanum, monolaurin was static to B. anthracis Sterne [1].
• Phenolic and triterpenoid antioxidants from Origanum majorana L. herb and extracts obtained with different solvents [11].
• The essential oil and various extracts obtained from Origanum acutidens and methanol extracts (MeOH) from callus cultures have been evaluated for their antioxidative, antimicrobial, and antiviral properties [12].
• At 1 mg/litre, an ethyl-acetate extract of the molluscicidal plant Origanum compactum Benth [13].

Gene context of Origanum

• Lemon balm and marjoram at a concentration of 1.5 % w/w increased by 150 % and 200 % respectively the antioxidant capacity of a salad portion [14].
• Chemical analyses were carried out in a GC-MSD, allowing the identification of around 24 compounds by use of the library of spectra of the equipment and injection of some standard compounds for both commercial and cultivated origanum samples [15].
• These results add to previous ones from a similar study of the discrimination of an aromatic spice, marjoram (Cain et al., 1990), in demonstrating that taste and smell weakness revealed in recent psychophysical tests can reveal themselves in the perception of everyday food and beverage preparations [16].
• Ursolic acid of Origanum majorana L. reduces Abeta-induced oxidative injury [8].
• The ursolic acid of Origanum majorana L. inhibited AChE activity in a dose-dependent and competitive/non-competitive type [17].

References