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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Olea


High impact information on Olea


Biological context of Olea


Anatomical context of Olea


Associations of Olea with chemical compounds

  • Horseradish peroxidase, bromelain, and ascorbate oxidase are recognized by the IgE of sera from patients who are hypersensitive to olive tree pollen [14].
  • Alternative pathways for phosphatidylcholine synthesis in olive (Olea europaea L.) callus cultures [15].
  • One of the most effective in terms of free radical scavenging is 3,4-dihydroxyphenyl ethanol or hydroxytyrosol (HT), a simple phenol found predominantly in Olea europea, or the olive plant [16].
  • Total RNA from the olive tree pollen was isolated, and a specific cDNA was amplified by the polymerase chain reaction using a degenerate oligonucleotide primer designed according to the NH2-terminal sequence of the protein [17].
  • Oleuropein (Ole) is the major phenolic constituent of the olive leaf (Olea europaea) and it is also present in olive oil and fruit [11].

Gene context of Olea

  • We report the characterisation of two cytochrome b5 genes and their spatial and temporal patterns of expression during development in olive, Olea europaea [18].
  • Oleuropein, a non-toxic secoiridoid derived from the olive tree, is a powerful antioxidant and anti-angiogenic agent [19].
  • Most of our monosensitized patients needed a high Olea pollen concentration in the atmosphere (around 400 grains/m3) to suffer at least from mild allergic rhinitis symptoms [3].
  • A cDNA encoding Ole e 3, a major allergen from olive-tree pollen, has been cloned and sequenced [20].
  • Cloning and Expression of the Olea europaea allergen Ole e 5, the pollen Cu/Zn superoxide dismutase [21].

Analytical, diagnostic and therapeutic context of Olea


  1. Identification, isolation, and characterization of Ole e 7, a new allergen of olive tree pollen. Tejera, M.L., Villalba, M., Batanero, E., Rodríguez, R. J. Allergy Clin. Immunol. (1999) [Pubmed]
  2. An allergen from Olea europaea pollen (Ole e 7) is associated with plant-derived food anaphylaxis. Florido Lopez, J.F., Quiralte Enriquez, J., Arias de Saavedra Alías, J.M., Saenz de San Pedro, B., Martin Casañez, E. Allergy (2002) [Pubmed]
  3. High levels of Olea europaea pollen and relation with clinical findings. Florido, J.F., Delgado, P.G., de San Pedro, B.S., Quiralte, J., de Saavedra, J.M., Peralta, V., Valenzuela, L.R. Int. Arch. Allergy Immunol. (1999) [Pubmed]
  4. Cross-reactivity to olive tree pollen and orchard grass pollen in patients with pollinosis. Miyahara, S., Nakada, M., Nishizaki, K., Kawarai, Y., Nishioka, K., Hino, H. Acta Med. Okayama (1997) [Pubmed]
  5. NMR solution structure of Ole e 6, a major allergen from olive tree pollen. Treviño, M.A., García-Mayoral, M.F., Barral, P., Villalba, M., Santoro, J., Rico, M., Rodríguez, R., Bruix, M. J. Biol. Chem. (2004) [Pubmed]
  6. Genetic restrictions in olive pollen allergy. Cardaba, B., Cortegano, I., Florido, F., Arrieta, I., Aceituno, E., del Pozo, V., Gallardo, S., Rojo, M., Palomino, P., Lahoz, C. J. Allergy Clin. Immunol. (2000) [Pubmed]
  7. IgE-binding and histamine-release capabilities of the main carbohydrate component isolated from the major allergen of olive tree pollen, Ole e 1. Batanero, E., Crespo, J.F., Monsalve, R.I., Martín-Esteban, M., Villalba, M., Rodríguez, R. J. Allergy Clin. Immunol. (1999) [Pubmed]
  8. Cloning and expression of the panallergen profilin and the major allergen (Ole e 1) from olive tree pollen. Asturias, J.A., Arilla, M.C., Gómez-Bayón, N., Martínez, J., Martínez, A., Palacios, R. J. Allergy Clin. Immunol. (1997) [Pubmed]
  9. Bioactive derivatives from oleuropein by a biotransformation on Olea europaea leaf extracts. Briante, R., La Cara, F., Febbraio, F., Patumi, M., Nucci, R. J. Biotechnol. (2002) [Pubmed]
  10. Reduced requirement for RNA editing in the mitochondrial cox3 transcript of Olea europaea L. Perrotta, G., Cavallotti, A., Quagliariello, C. Curr. Genet. (1997) [Pubmed]
  11. Differential effects of oleuropein, a biophenol from Olea europaea, on anionic and zwiterionic phospholipid model membranes. Caturla, N., Pérez-Fons, L., Estepa, A., Micol, V. Chem. Phys. Lipids (2005) [Pubmed]
  12. Degradation of hemicellulosic and cellulosic polysaccharides in pickled green olives. Sánchez-Romero, C., Guillén, R., Heredia, A., Jiménez, A., Fernández-Bolaños, J. J. Food Prot. (1998) [Pubmed]
  13. Chlorophyll and carotenoid degradation mediated by thylakoid-associated peroxidative activity in olives (Olea europaea) cv. hojiblanca. Gandul-Rojas, B., Roca, M., Mínguez-Mosquera, M.I. J. Plant Physiol. (2004) [Pubmed]
  14. Cross-reactivity between the major allergen from olive pollen and unrelated glycoproteins: evidence of an epitope in the glycan moiety of the allergen. Batanero, E., Villalba, M., Monsalve, R.I., Rodríguez, R. J. Allergy Clin. Immunol. (1996) [Pubmed]
  15. Alternative pathways for phosphatidylcholine synthesis in olive (Olea europaea L.) callus cultures. Williams, M., Harwood, J.L. Biochem. J. (1994) [Pubmed]
  16. Hydrolyzed olive vegetation water in mice has anti-inflammatory activity. Bitler, C.M., Viale, T.M., Damaj, B., Crea, R. J. Nutr. (2005) [Pubmed]
  17. Purification, amino acid sequence and immunological characterization of Ole e 6, a cysteine-enriched allergen from olive tree pollen. Batanero, E., Ledesma, A., Villalba, M., Rodríguez, R. FEBS Lett. (1997) [Pubmed]
  18. Temporal and spatial gene expression of cytochrome B5 during flower and fruit development in olives. Martsinkovskaya, A.I., Poghosyan, Z.P., Haralampidis, K., Murphy, D.J., Hatzopoulos, P. Plant Mol. Biol. (1999) [Pubmed]
  19. Oleuropein, a non-toxic olive iridoid, is an anti-tumor agent and cytoskeleton disruptor. Hamdi, H.K., Castellon, R. Biochem. Biophys. Res. Commun. (2005) [Pubmed]
  20. Molecular cloning and expression of active Ole e 3, a major allergen from olive-tree pollen and member of a novel family of Ca2+-binding proteins (polcalcins) involved in allergy. Ledesma, A., Villalba, M., Batanero, E., Rodríguez, R. Eur. J. Biochem. (1998) [Pubmed]
  21. Cloning and Expression of the Olea europaea allergen Ole e 5, the pollen Cu/Zn superoxide dismutase. Butteroni, C., Afferni, C., Barletta, B., Iacovacci, P., Corinti, S., Brunetto, B., Tinghino, R., Ariano, R., Panzani, R.C., Pini, C., Di Felice, G. Int. Arch. Allergy Immunol. (2005) [Pubmed]
  22. Monoclonal antibodies against Olea europaea major allergen: allergenic activity of affinity-purified allergen and depleted extract and development of a radioimmunoassay for the quantitation of the allergen. Lombardero, M., Quirce, S., Duffort, O., Barber, D., Carpizo, J., Chamorro, M.J., Lezaun, A., Carreira, J. J. Allergy Clin. Immunol. (1992) [Pubmed]
  23. Purification of allergens by high-performance liquid chromatography. IV. Purification of the allergen of olive pollen (Olea europea). Rubio, N., Brieva, A., Alcazar, B. J. Chromatogr. (1987) [Pubmed]
  24. Molecular cloning and characterization of genes encoding two microsomal oleate desaturases (FAD2) from olive. Hernández, M.L., Mancha, M., Martínez-Rivas, J.M. Phytochemistry (2005) [Pubmed]
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