Disease relevance of Gram-Negative Anaerobic Bacteria

• Gram-positive anaerobic bacteria were mostly sensitive to penicillin-G but most of the Gram-negative anaerobic bacteria were resistant and some Bacteroides fragilis strains produced beta-lactamase [1].

High impact information on Gram-Negative Anaerobic Bacteria

• Time-kill studies examined the activities of telithromycin (HMR 3647), erythromycin A, azithromycin, clarithromycin, roxithromycin, clindamycin, pristinamycin, amoxicillin-clavulanate, and metronidazole against 11 gram-positive and gram-negative anaerobic bacteria [2].
• Interactions of ciprofloxacin with clindamycin, metronidazole, cefoxitin, cefotaxime, and mezlocillin against gram-positive and gram-negative anaerobic bacteria [3].
• Current data are summarized on the comparative susceptibility of Gram-positive and Gram-negative anaerobic bacteria to piperacillin/tazobactam and other anti-anaerobe agents [4].
• Rapid presumptive identification of black-pigmented gram-negative anaerobic bacteria by using 4-methylumbelliferone derivatives [5].
• Therefore, the use of these preliminary identification tests can assist in the correct grouping of anaerobes and accurately predict significant clindamycin resistance in gram-negative anaerobic bacteria [6].

Chemical compound and disease context of Gram-Negative Anaerobic Bacteria

• The results were related to the viable bacteria count of root canal samples, phenol/water-extracted lipopolysaccharides (LPS) from different gram-negative anaerobic bacteria, and to different fractions of inflammation exudate [7].
• Virtually all Gram-positive and Gram-negative anaerobic bacteria tested were susceptible to meropenem (defined as MICs less than or equal to 8 micrograms/ml) with 99.8% of the isolates inhibited by less than or equal to 4 micrograms/ml [8].
• The ability of cefoxitin, clindamycin, imipenem, meropenem, metronidazole and piperacillin-tazobactam to cause gram-negative anaerobic bacteria to release endotoxin and the influence of such liberated endotoxin on antibiotic efficacy were investigated in in-vivo experiments in animal models [9].
• The inactivation of amoxicillin by beta-lactamases of gram negative anaerobic bacteria can be circumvented by the addition of clavulanic acid, a beta-lactamases inhibitor [10].
• The in vitro activity of PH-027 in comparison with those of linezolid and other antimicrobial agents was evaluated against 201 clinical isolates of gram-positive and gram-negative anaerobic bacteria by agar dilution and Etest methods [11].

Gene context of Gram-Negative Anaerobic Bacteria

• Outer-membrane pore-forming proteins in gram-negative anaerobic bacteria [12].

Analytical, diagnostic and therapeutic context of Gram-Negative Anaerobic Bacteria

• Minimum inhibitory concentration determinations in 23 strains of gram-negative anaerobic bacteria detected resistance to enrofloxacin and clindamycin [13].

References