Chemical Compound Review:
AC1NQXVM (2R,3E,5R)-3-(2- hydroxyethylidene)-7-oxo-4...
Synonyms:
SureCN2292022, C11833, 85-53-0, 62319-53-3, Isoclavulanic acid
Li,
Lee,
Castillo,
Hixon,
Pujol,
Doppalapudi,
Shepard,
Wahl,
Lobl,
Chan,
Lucena,
Camargo,
Andrade,
Perez-Sanchez,
Sanchez De La Cuesta,
- Clavulanic acid and susceptibility of Bacteroides fragilis to penicillin. Wise, R. Lancet (1977)
- Beta-lactamase inhibitors and reversal of antibiotic resistance. Sutherland, R. Trends Pharmacol. Sci. (1991)
- Systemic antibiotic prophylaxis after gastrointestinal hemorrhage in cirrhotic patients with a high risk of infection. Pauwels, A., Mostefa-Kara, N., Debenes, B., Degoutte, E., Lévy, V.G. Hepatology (1996)
- Amoxicillin-clavulanic acid therapy of spontaneous bacterial peritonitis: a prospective study of twenty-seven cases in cirrhotic patients. Grange, J.D., Amiot, X., Grange, V., Gutmann, L., Biour, M., Bodin, F., Poupon, R. Hepatology (1990)
- Understanding resistance to beta-lactams and beta-lactamase inhibitors in the SHV beta-lactamase: lessons from the mutagenesis of SER-130. Helfand, M.S., Bethel, C.R., Hujer, A.M., Hujer, K.M., Anderson, V.E., Bonomo, R.A. J. Biol. Chem. (2003)
- Comparison of two clinical scales for causality assessment in hepatotoxicity. Lucena, M.I., Camargo, R., Andrade, R.J., Perez-Sanchez, C.J., Sanchez De La Cuesta, F. Hepatology (2001)
- In vitro studies of plasmid-mediated penicillinase from Streptococcus faecalis suggest a staphylococcal origin. Murray, B.E., Mederski-Samoraj, B., Foster, S.K., Brunton, J.L., Harford, P. J. Clin. Invest. (1986)
- Clavulanic acid and amoxycillin: a clinical, bacteriological, and pharmacological study. Ball, A.P., Geddes, A.M., Davey, P.G., Farrell, I.D., Brookes, G.R. Lancet (1980)
- Structure of beta-lactam synthetase reveals how to synthesize antibiotics instead of asparagine. Miller, M.T., Bachmann, B.O., Townsend, C.A., Rosenzweig, A.C. Nat. Struct. Biol. (2001)
- beta-Lactam synthetase: a new biosynthetic enzyme. Bachmann, B.O., Li, R., Townsend, C.A. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Systemic antibiotic therapy prevents bacterial infection in cirrhotic patients with gastrointestinal hemorrhage. Blaise, M., Pateron, D., Trinchet, J.C., Levacher, S., Beaugrand, M., Pourriat, J.L. Hepatology (1994)
- Noncomparative trial of ticarcillin plus clavulanic acid in skin and soft tissue infections. LeFrock, J.L., Johnson, E.S., Smith, L.G., Rosenberg, E. Am. J. Med. (1985)
- Efficacy and safety of ticarcillin plus clavulanic acid and piperacillin in patients with lower respiratory tract infections. Link, A.S. Am. J. Med. (1985)
- Comparative clinical evaluation of ticarcillin plus clavulanic acid versus clindamycin plus gentamicin in treatment of post-cesarean endomyometritis. Apuzzio, J.J., Kaminski, Z., Gamesh, V., Louria, D.B. Am. J. Med. (1985)
- Comparison of ticarcillin plus clavulanic acid with cefoxitin in the treatment of female pelvic infection. Pastorek, J.G., Aldridge, K.E., Cunningham, G.L., Faro, S., Graffeo, S., McNeeley, G.S., Tan, J.S. Am. J. Med. (1985)
- ORF17 from the clavulanic acid biosynthesis gene cluster catalyzes the ATP-dependent formation of N-glycyl-clavaminic acid. Arulanantham, H., Kershaw, N.J., Hewitson, K.S., Hughes, C.E., Thirkettle, J.E., Schofield, C.J. J. Biol. Chem. (2006)
- Site-directed mutagenesis at the active site of Escherichia coli TEM-1 beta-lactamase. Suicide inhibitor-resistant mutants reveal the role of arginine 244 and methionine 69 in catalysis. Delaire, M., Labia, R., Samama, J.P., Masson, J.M. J. Biol. Chem. (1992)
- Clinical pharmacology of timentin (ticarcillin and clavulanic acid). Bodey, G.P., Yeo, E., Ho, D.H., Rolston, K., LeBlanc, B. Clin. Pharmacol. Ther. (1985)
- Class A beta-lactamases--enzyme-inhibitor interactions and resistance. Yang, Y., Rasmussen, B.A., Shlaes, D.M. Pharmacol. Ther. (1999)
- Bactericidal activity against Haemophilus influenzae of cerebrospinal fluid of patients given amoxicillin-clavulanic acid. Decazes, J.M., Bure, A., Wolff, M., Kitzis, M.D., Pangon, B., Modai, J. Antimicrob. Agents Chemother. (1987)
- Amoxycillin-clavulanic acid combination in bronchopulmonary infection due to beta-lactamase-producing Branhamella catarrhalis. Preliminary report. Thornley, P.E., Aitken, J.M., Nichol, G.M., Slevin, N.J. Drugs (1986)
- Penetration of amoxycillin/clavulanic acid into bronchial mucosa with different dosing regimens. Gould, I.M., Harvey, G., Golder, D., Reid, T.M., Watt, S.J., Friend, J.A., Legge, J.S., Douglas, J.G. Thorax (1994)
- Abnormal physiological properties and altered cell wall composition in Streptococcus pneumoniae grown in the presence of clavulanic acid. Severin, A., Severina, E., Tomasz, A. Antimicrob. Agents Chemother. (1997)
- Comparison of concentrations of two doses of clavulanic acid (200 and 400 milligrams) administered with amoxicillin (2,000 milligrams) in tissues of patients undergoing colorectal surgery. Martin, C., Mallet, M.N., Sastre, B., Viviand, X., Martin, A., De Micco, P., Gouin, F. Antimicrob. Agents Chemother. (1995)
- Risk of acute liver injury associated with the combination of amoxicillin and clavulanic acid. García Rodríguez, L.A., Stricker, B.H., Zimmerman, H.J. Arch. Intern. Med. (1996)
- Safety and efficacy of ticarcillin plus clavulanic acid in the treatment of infections of soft tissue, bone, and joint. Johnson, C.C., Reinhardt, J.F., Wallace, S.L., Terpenning, M.S., Helsel, C.L., Mulligan, M.E., Finegold, S.M., George, W.L. Am. J. Med. (1985)
- Different proteins bind to the butyrolactone receptor protein ARE sequence located upstream of the regulatory ccaR gene of Streptomyces clavuligerus. Santamarta, I., Pérez-Redondo, R., Lorenzana, L.M., Martín, J.F., Liras, P. Mol. Microbiol. (2005)
- Ticarcillin plus clavulanic acid versus cefoxitin in the prophylaxis of infection after cesarean section. Saltzman, D.H., Eron, L.J., Toy, C., Protomastro, L.J., Sites, J.G. Am. J. Med. (1985)
- Antibacterial activity of ticarcillin in the presence of clavulanate potassium. Sutherland, R., Beale, A.S., Boon, R.J., Griffin, K.E., Slocombe, B., Stokes, D.H., White, A.R. Am. J. Med. (1985)
- Clavulanic acid inactivation of SHV-1 and the inhibitor-resistant S130G SHV-1 beta-lactamase. Insights into the mechanism of inhibition. Sulton, D., Pagan-Rodriguez, D., Zhou, X., Liu, Y., Hujer, A.M., Bethel, C.R., Helfand, M.S., Thomson, J.M., Anderson, V.E., Buynak, J.D., Ng, L.M., Bonomo, R.A. J. Biol. Chem. (2005)
- NB2001, a novel antibacterial agent with broad-spectrum activity and enhanced potency against beta-lactamase-producing strains. Li, Q., Lee, J.Y., Castillo, R., Hixon, M.S., Pujol, C., Doppalapudi, V.R., Shepard, H.M., Wahl, G.M., Lobl, T.J., Chan, M.F. Antimicrob. Agents Chemother. (2002)
- Characterization of the Streptomyces clavuligerus argC gene encoding N-acetylglutamyl-phosphate reductase: expression in Streptomyces lividans and effect on clavulanic acid production. Ludovice, M., Martin, J.F., Carrachas, P., Liras, P. J. Bacteriol. (1992)
- Beta-lactamase inhibitors from laboratory to clinic. Bush, K. Clin. Microbiol. Rev. (1988)
- Pharmacology of ticarcillin combined with clavulanic acid in humans. Scully, B.E., Chin, N.X., Neu, H.C. Am. J. Med. (1985)
- VEB-1-like extended-spectrum beta-lactamases in Pseudomonas aeruginosa, Kuwait. Poirel, L., Rotimi, V.O., Mokaddas, E.M., Karim, A., Nordmann, P. Emerging Infect. Dis. (2001)
- Pharmacokinetics of amoxicillin and clavulanic acid administered alone and in combination. Adam, D., de Visser, I., Koeppe, P. Antimicrob. Agents Chemother. (1982)
- Positive direct antiglobulin tests due to clavulanic acid. Williams, M.E., Thomas, D., Harman, C.P., Mintz, P.D., Donowitz, G.R. Antimicrob. Agents Chemother. (1985)
- Inhibition of TEM-2 beta-lactamase from Escherichia coli by clavulanic acid: observation of intermediates by electrospray ionization mass spectrometry. Brown, R.P., Aplin, R.T., Schofield, C.J. Biochemistry (1996)