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Disease relevance of Guinea-Bissau


High impact information on Guinea-Bissau

  • Effect of vitamin A supplementation on measles-specific antibody levels in Guinea-Bissau [5].
  • Measles and atopy in Guinea-Bissau [6].
  • Sensitivity of primers (at least one of the four primer pairs was positive) to HIV-2-seropositive samples was 100% (all nine) in Guinea-Bissau, 71% (12/17) in Côte d'Ivoire, 100% (all 20) in Gambian AIDS patients, and 85% (17/20) in Gambian pregnant women [7].
  • In a community study in Guinea-Bissau, West Africa, 47 HIV-2-seropositive cases and 87 matched controls were evaluated immunologically using immuno-alkaline phosphatase linked to avidin-biotin complex for the assessment of CD4 and CD8 status [8].
  • Strains from patients originating in Mali also clustered in subtype A but distinctly from the Cape Verde or Guinea Bissau strains [9].

Chemical compound and disease context of Guinea-Bissau


Biological context of Guinea-Bissau


Associations of Guinea-Bissau with chemical compounds


Gene context of Guinea-Bissau

  • We determined, in a population from Guinea-Bissau, the frequencies of CYP3A4 and NAT2 variants expected to be prevalent among Africans, due to the high frequency previously observed in African Americans [15].
  • STUDY DESIGN AND METHODS: Fourteen HTLV antibody assays were evaluated by using well-characterized panels of sera from Guinea-Bissau, West Africa, and Sweden [16].
  • SUBJECTS: In 1996, 28 Angolan doctors, 26 from Guinea-Bissau, 11 from Mozambique and three from S Tomé and Principe answered a self-administered questionnaire [17].

Analytical, diagnostic and therapeutic context of Guinea-Bissau


  1. Biochemical heterogeneity of Mycobacterium tuberculosis complex isolates in Guinea-Bissau. Hoffner, S.E., Svenson, S.B., Norberg, R., Dias, F., Ghebremichael, S., Källenius, G. J. Clin. Microbiol. (1993) [Pubmed]
  2. Treatment of children with Plasmodium falciparum malaria with chloroquine in Guinea-Bissau. Kofoed, P.E., Lopez, F., Johansson, P., Sandström, A., Hedegaard, K., Aaby, P., Rombo, L. Am. J. Trop. Med. Hyg. (2002) [Pubmed]
  3. Genetic markers of resistance to pyrimethamine and sulfonamides in Plasmodium falciparum parasites compared with the resistance patterns in isolates of Escherichia coli from the same children in Guinea-Bissau. Kofoed, P.E., Alfrangis, M., Poulsen, A., Rodrigues, A., Gjedde, S.B., Rønn, A., Rombo, L. Trop. Med. Int. Health (2004) [Pubmed]
  4. Longstanding presence of HIV-2 infection in Guinea-Bissau (West Africa). Piedade, J., Venenno, T., Prieto, E., Albuquerque, R., Esteves, A., Parreira, R., Canas-Ferreira, W.F. Acta Trop. (2000) [Pubmed]
  5. Effect of vitamin A supplementation on measles-specific antibody levels in Guinea-Bissau. Benn, C.S., Balde, A., George, E., Kidd, M., Whittle, H., Lisse, I.M., Aaby, P. Lancet (2002) [Pubmed]
  6. Measles and atopy in Guinea-Bissau. Shaheen, S.O., Aaby, P., Hall, A.J., Barker, D.J., Heyes, C.B., Shiell, A.W., Goudiaby, A. Lancet (1996) [Pubmed]
  7. Improved detection of HIV-2 proviral DNA in dually seroreactive individuals by PCR. Ishikawa, K., Fransen, K., Ariyoshi, K., Nkengasong, J.N., Janssens, W., Heyndrickx, L., Whittle, H., Diallo, M.O., Ghys, P.D., Coulibaly, I.M., Greenberg, A.E., Piedade, J., Canas-Ferreira, W., van der Groen, G. AIDS (1998) [Pubmed]
  8. Immunodeficiency in HIV-2 infection: a community study from Guinea-Bissau. Lisse, I.M., Poulsen, A.G., Aaby, P., Normark, M., Kvinesdal, B., Dias, F., Mølbak, K., Knudsen, K. AIDS (1990) [Pubmed]
  9. Variability of human immunodeficiency virus type 2 (hiv-2) infecting patients living in france. Damond, F., Apetrei, C., Robertson, D.L., Souquière, S., Leprêtre, A., Matheron, S., Plantier, J.C., Brun-Vézinet, F., Simon, F. Virology (2001) [Pubmed]
  10. Drug susceptibility in Mycobacterium tuberculosis of a sample of patients in Guinea Bissau. Dias, F., Michael, S.G., Hoffner, S.E., Martins, L., Norberg, R., Källenius, G. Tuber. Lung Dis. (1993) [Pubmed]
  11. Randomised trial of effect of vitamin A supplementation on antibody response to measles vaccine in Guinea-Bissau, west Africa. Benn, C.S., Aaby, P., Balé, C., Olsen, J., Michaelsen, K.F., George, E., Whittle, H. Lancet (1997) [Pubmed]
  12. Effect of sublingual misoprostol on severe postpartum haemorrhage in a primary health centre in Guinea-Bissau: randomised double blind clinical trial. Høj, L., Cardoso, P., Nielsen, B.B., Hvidman, L., Nielsen, J., Aaby, P. BMJ (2005) [Pubmed]
  13. Control of endophagic Anopheles mosquitoes and human malaria in Guinea Bissau, West Africa by permethrin-treated bed nets. Jaenson, T.G., Gomes, M.J., Barreto dos Santos, R.C., Petrarca, V., Fortini, D., Evora, J., Crato, J. Trans. R. Soc. Trop. Med. Hyg. (1994) [Pubmed]
  14. Treatment of uncomplicated malaria in children in Guinea-Bissau with chloroquine, quinine, and sulfadoxine-pyrimethamine. Kofoed, P.E., Có, F., Johansson, P., Dias, F., Cabral, C., Hedegaard, K., Aaby, P., Rombo, L. Trans. R. Soc. Trop. Med. Hyg. (2002) [Pubmed]
  15. CYP3A4*1B and NAT2*14 alleles in a native African population. Cavaco, I., Reis, R., Gil, J.P., Ribeiro, V. Clin. Chem. Lab. Med. (2003) [Pubmed]
  16. Comparative evaluation of 14 immunoassays for detection of antibodies to the human T-lymphotropic virus types I and II using panels of sera from Sweden and West Africa. Andersson, S., Thorstensson, R., Ramirez, K.G., Krook, A., von Sydow, M., Dias, F., Biberfeld, G. Transfusion (1999) [Pubmed]
  17. How and why public sector doctors engage in private practice in Portuguese-speaking African countries. Ferrinho, P., Van Lerberghe, W., Julien, M.R., Fresta, E., Gomes, A., Dias, F., Gonçalves, A., Bäckström, B. Health policy and planning. (1998) [Pubmed]
  18. Investigation of chloroquine intake in Biombo region, Guinea Bissau. Vigário, A.M., Eggelte, T.A., Costa, A., Seixas, E., Rosário, V.E. Appl. Parasitol. (1994) [Pubmed]
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