Disease relevance of Mozambique

• Agranulocytosis in Mozambique due to amidopyrine, a drug withdrawn in the west [1].
• Stevens-Johnson syndrome after mass prophylaxis with sulfadoxine for cholera in Mozambique [2].
• Molecular identification of pathogenicity genes and ERIC types in Vibrio cholerae O1 epidemic strains from Mozambique [3].
• Polymerase chain reaction for detection of hepatitis B virus DNA in HBsAg seronegative patients with hepatocellular carcinoma from Mozambique [4].
• Sporadic methicillin resistance in community acquired Staphylococcus aureus in Mozambique [5].

High impact information on Mozambique

• HCC is an endemic disease in Mozambique and accounts for up to two thirds of all tumours in men [6].
• Chloroquine-resistant malaria in Mozambique [7].
• OBJECTIVE: The objective of this study was to assess the barriers to care for patients with insulin-requiring diabetes in Mozambique and Zambia. RESEARCH DESIGN AND METHODS: We used the Rapid Assessment Protocol for Insulin Access to collect information through interviews, discussions, site visits, and document reviews [8].
• An approximately 1.3-kb region including the rp49 gene plus its 5' and 3' flanking regions was sequenced in 24 lines of Drosophila simulans (10 from Spain and 14 from Mozambique) [9].
• The levels of haplotype diversity within the lineages defined by two single-nucleotide polymorphisms (SNPs) (-13910 C/T and -22018 G/A) associated with human lactase persistence were assessed with four fast-evolving microsatellite loci in 794 chromosomes from Portugal, Italy, Fulbe from Cameroon, São Tomé and Mozambique [10].

Chemical compound and disease context of Mozambique

• A case of concurrent chloroquine- and Fransidar-resistant Plasmodium falciparum malaria imported into Zimbabwe by an adult male Zimbabwean from either Malawi or Mozambique is reported [11].
• Field studies on animal trypanosomiasis in Mozambique. I. Effectiveness of the prophylactic drugs isometamidium chloride and pyrithidium bromide [12].

Biological context of Mozambique

• The three common haplotypes (H1, H2 and H3) show a combined frequency of 95% in Portugal and 87% in Mozambique [13].
• The short tandem repeat systems (STRs) D12S391, HUMFIBRA/FGA and HUMACTBP2 (SE33) were studied in a population of unrelated individuals from the Maputo area of south Mozambique [14].
• Allele frequencies for twelve STRs included in the AmpFlSTR Profiler Plus kit (D3S1358, VWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317 and D7S820) and GenePrint CTTv kit (VWA, TH01, TPO and CSF1PO) were estimated from a sample of 110 unrelated individuals from Mozambique [15].

Anatomical context of Mozambique

• Serological analysis of cyst fluid of T. solium cysticerci obtained in China and Indonesia and from Mozambique and Ecuador indicates geographical differences in their banding patterns [16].
• Erythrocyte transketolase (ETK), glutathione reductase (EGR) and glutamate pyruvate transaminase (EGPT) enzyme activities and coenzyme effects (in vitro coenzyme stimulation) were studied in 30 random, 10 primary hepatoma, and 3 pellagrins natives from Mozambique [17].

Associations of Mozambique with chemical compounds

• The frequency of the C5+ variant in Rhodesian, Malawian and Mozambique Africans, although varying from tribe to tribe within the range of 0-8%, averages 3% in each group [18].
• Compliance with C + P among 3734 soldiers on duty in Somalia for 3.8 +/- 1.8 months and with mefloquine among 1386 soldiers on duty in Mozambique for 3.4 +/- 1.5 months was 90.3% and 95.7%, respectively (P < 0.01) [19].
• To compare the efficacy and side effects of intramuscular (i.m.) and intravenous (i.v.) quinine, children in Mozambique with severe and complicated malaria between 6 months and 7 years were randomized to treatment with i.m. or i.v. quinine, both in a dosage of quinine dihydrochloride 20 mg/kg followed by 10 mg/kg every 8 h [20].
• Two known cembrane diterpenes, flaccidoxide (1) and (1Z,3E,7E,11S, 12S,14S)-11,12-epoxy cembra-1,3,7-trien-14-ol (2), and the new cembrane diterpene flaccidoxide-13-acetate (3) were isolated from specimens of Cladiella kashmani collected off Ponto do Oura, Mozambique [21].
• The residual life of bendiocarb: a field-based evaluation from Mozambique [22].

Gene context of Mozambique

• With regard to the polymorphisms aP, PGM1 and PGM2, the results derived from South Africa and Mozambique exhibit reverse patterns of deviations from the null hypothesis [23].
• Genetic study of African populations: polymorphisms of the plasma proteins TF, PL, F13B, and AHSG in populations of Namibia and Mozambique [24].
• The prevalence of mutations in dhfr and dhps in relation to S/P efficacy was studied in four sites of differing endemicity in Sudan, Mozambique, and Tanzania. The sites were organized in order of increasing resistance and a significant increase in the prevalence of triple mutations in codons c51, c59, and c108 of dhfr was observed [25].
• PLG was compared with the current protocol used in two Mozambique hospitals, based on FSC/SSC gating and CD3/CD4/CD8 staining [26].
• Haematological study in Cabo Delgado province, Mozambique; sickle cell trait and G6PD deficiency [27].

References