Chemical Compound Review:
Miambutol (2S)-2-[2-[[(2S)-1- hydroxybutan-2...
Synonyms:
Purderal, Etambutol, Etapiam, Myambutol, Mycobutol, ...
Ribera,
Azuaje,
Lopez,
Domingo,
Curran,
Feijoo,
Pou,
Sánchez,
Sambeat,
Colomer,
Lopez-Colomes,
Crespo,
Falcó,
Ocaña,
Pahissa,
Pallen,
Chaudhuri,
Khan,
Graham,
Bell,
Nyirongo,
Hartkoorn,
Ward,
Molyneux,
Nikonenko,
Protopopova,
Samala,
Einck,
Nacy,
Burman,
Goldberg,
Johnson,
Muzanye,
Engle,
Mosher,
Choudhri,
Daley,
Munsiff,
Zhao,
Vernon,
Chaisson,
Jia,
Tomaszewski,
Hanrahan,
Coward,
Noker,
Gorman,
Nikonenko,
Protopopova,
Matsuba,
Suzuki,
Tanaka,
- A comparison of two regimens for the treatment of Mycobacterium avium complex bacteremia in AIDS: rifabutin, ethambutol, and clarithromycin versus rifampin, ethambutol, clofazimine, and ciprofloxacin. Canadian HIV Trials Network Protocol 010 Study Group. Shafran, S.D., Singer, J., Zarowny, D.P., Phillips, P., Salit, I., Walmsley, S.L., Fong, I.W., Gill, M.J., Rachlis, A.R., Lalonde, R.G., Fanning, M.M., Tsoukas, C.M. N. Engl. J. Med. (1996)
- The emb operon, a gene cluster of Mycobacterium tuberculosis involved in resistance to ethambutol. Telenti, A., Philipp, W.J., Sreevatsan, S., Bernasconi, C., Stockbauer, K.E., Wieles, B., Musser, J.M., Jacobs, W.R. Nat. Med. (1997)
- Hydroxycobalamin for ethambutol-induced optic neuropathy. Guerra, R., Casu, L. Lancet (1981)
- Identification of a novel arabinofuranosyltransferase (AftA) involved in cell wall arabinan biosynthesis in Mycobacterium tuberculosis. Alderwick, L.J., Seidel, M., Sahm, H., Besra, G.S., Eggeling, L. J. Biol. Chem. (2006)
- Rapid-onset reversible ocular toxicity from ethambutol therapy. Schild, H.S., Fox, B.C. Am. J. Med. (1991)
- Ocular adverse effects associated with systemic medications : recognition and management. Santaella, R.M., Fraunfelder, F.W. Drugs (2007)
- Pharmacokinetic interaction between rifampicin and the once-daily combination of saquinavir and low-dose ritonavir in HIV-infected patients with tuberculosis. Ribera, E., Azuaje, C., Lopez, R.M., Domingo, P., Curran, A., Feijoo, M., Pou, L., Sánchez, P., Sambeat, M.A., Colomer, J., Lopez-Colomes, J.L., Crespo, M., Falcó, V., Ocaña, I., Pahissa, A. J. Antimicrob. Chemother. (2007)
- Specific inhibition of spermidine synthase from mycobacteria by ethambutol. Pöso, H., Paulin, L., Brander, E. Lancet (1983)
- Ethambutol plus isoniazid compared with rifampicin plus isoniazid in antituberculosis continuation treatment. Lees, A.W., Allan, G.W., Smith, J., Tyrrell, W.F. Lancet (1977)
- Isoniazid and ethambutol absorption with jejunoileal bypass. Polk, R.E., Tenenbaum, M., Kline, B. Ann. Intern. Med. (1978)
- Identification and active expression of the Mycobacterium tuberculosis gene encoding 5-phospho-{alpha}-d-ribose-1-diphosphate: decaprenyl-phosphate 5-phosphoribosyltransferase, the first enzyme committed to decaprenylphosphoryl-d-arabinose synthesis. Huang, H., Scherman, M.S., D'Haeze, W., Vereecke, D., Holsters, M., Crick, D.C., McNeil, M.R. J. Biol. Chem. (2005)
- Moxifloxacin versus ethambutol in the first 2 months of treatment for pulmonary tuberculosis. Burman, W.J., Goldberg, S., Johnson, J.L., Muzanye, G., Engle, M., Mosher, A.W., Choudhri, S., Daley, C.L., Munsiff, S.S., Zhao, Z., Vernon, A., Chaisson, R.E. Am. J. Respir. Crit. Care Med. (2006)
- Low levels of pyrazinamide and ethambutol in children with tuberculosis and impact of age, nutritional status, and human immunodeficiency virus infection. Graham, S.M., Bell, D.J., Nyirongo, S., Hartkoorn, R., Ward, S.A., Molyneux, E.M. Antimicrob. Agents Chemother. (2006)
- Postantibiotic effect of clarithromycin alone and combined with ethambutol against Mycobacterium avium complex. Ellis, L.C., Benson, C.A., Koenig, G.I., Trenholme, G.M. Antimicrob. Agents Chemother. (1995)
- Randomized, placebo-controlled trial of rifampin, ethambutol, and ciprofloxacin for AIDS patients with disseminated Mycobacterium avium complex infection. Jacobson, M.A., Yajko, D., Northfelt, D., Charlebois, E., Gary, D., Brosgart, C., Sanders, C.A., Hadley, W.K. J. Infect. Dis. (1993)
- Sparfloxacin, ethambutol, and cortisol receptor inhibitor RU-40 555 treatment for disseminated Mycobacterium avium complex infection of normal C57BL/6 mice. Perronne, C., Cohen, Y., Truffot-Pernot, C., Grosset, J., Vildé, J.L., Pocidalo, J.J. Antimicrob. Agents Chemother. (1992)
- Deletion of Cg-emb in corynebacterianeae leads to a novel truncated cell wall arabinogalactan, whereas inactivation of Cg-ubiA results in an arabinan-deficient mutant with a cell wall galactan core. Alderwick, L.J., Radmacher, E., Seidel, M., Gande, R., Hitchen, P.G., Morris, H.R., Dell, A., Sahm, H., Eggeling, L., Besra, G.S. J. Biol. Chem. (2005)
- Bacterial FHA domains: neglected players in the phospho-threonine signalling game? Pallen, M., Chaudhuri, R., Khan, A. Trends Microbiol. (2002)
- Kinetics of oral ethambutol in the normal subject. Lee, C.S., Gambertoglio, J.G., Brater, D.C., Benet, L.Z. Clin. Pharmacol. Ther. (1977)
- Role of embB codon 306 mutations in Mycobacterium tuberculosis revisited: a novel association with broad drug resistance and IS6110 clustering rather than ethambutol resistance. Hazbón, M.H., Bobadilla del Valle, M., Guerrero, M.I., Varma-Basil, M., Filliol, I., Cavatore, M., Colangeli, R., Safi, H., Billman-Jacobe, H., Lavender, C., Fyfe, J., García-García, L., Davidow, A., Brimacombe, M., León, C.I., Porras, T., Bose, M., Chaves, F., Eisenach, K.D., Sifuentes-Osornio, J., Ponce de León, A., Cave, M.D., Alland, D. Antimicrob. Agents Chemother. (2005)
- Visual evoked potentials in the detection of subclinical optic toxic effects secondary to ethambutol. Yiannikas, C., Walsh, J.C., McLeod, J.G. Arch. Neurol. (1983)
- Antibiotic uptake by alveolar macrophages of smokers. Hand, W.L., Boozer, R.M., King-Thompson, N.L. Antimicrob. Agents Chemother. (1985)
- Ethambutol is toxic to retinal ganglion cells via an excitotoxic pathway. Heng, J.E., Vorwerk, C.K., Lessell, E., Zurakowski, D., Levin, L.A., Dreyer, E.B. Invest. Ophthalmol. Vis. Sci. (1999)
- In vivo activities of newer rifamycin analogs against Mycobacterium avium infection. Klemens, S.P., Cynamon, M.H. Antimicrob. Agents Chemother. (1991)
- Altered expression profile of the surface glycopeptidolipids in drug-resistant clinical isolates of Mycobacterium avium complex. Khoo, K.H., Jarboe, E., Barker, A., Torrelles, J., Kuo, C.W., Chatterjee, D. J. Biol. Chem. (1999)
- Incidence of serious side effects from first-line antituberculosis drugs among patients treated for active tuberculosis. Yee, D., Valiquette, C., Pelletier, M., Parisien, I., Rocher, I., Menzies, D. Am. J. Respir. Crit. Care Med. (2003)
- In vitro activities of U-100592 and U-100766, novel oxazolidinone antibacterial agents. Zurenko, G.E., Yagi, B.H., Schaadt, R.D., Allison, J.W., Kilburn, J.O., Glickman, S.E., Hutchinson, D.K., Barbachyn, M.R., Brickner, S.J. Antimicrob. Agents Chemother. (1996)
- Deletion of the Mycobacterium tuberculosis pknH gene confers a higher bacillary load during the chronic phase of infection in BALB/c mice. Papavinasasundaram, K.G., Chan, B., Chung, J.H., Colston, M.J., Davis, E.O., Av-Gay, Y. J. Bacteriol. (2005)
- Multidrug resistance following expression of the Escherichia coli marA gene in Mycobacterium smegmatis. McDermott, P.F., White, D.G., Podglajen, I., Alekshun, M.N., Levy, S.B. J. Bacteriol. (1998)
- Leber's hereditary optic neuropathy mutations in ethambutol-induced optic neuropathy. Hwang, J.M., Kim, J., Park, S.S. J. Neurol. (2003)
- Association of the Rv0679c protein with lipids and carbohydrates in Mycobacterium tuberculosis/Mycobacterium bovis BCG. Matsuba, T., Suzuki, Y., Tanaka, Y. Arch. Microbiol. (2007)
- Caspase inhibitors block zinc-chelator induced death of retinal ganglion cells. Shindler, K.S., Zurakowski, D., Dreyer, E.B. Neuroreport (2000)
- Tuberculoid tenosynovitis and carpal tunnel syndrome caused by Mycobacterium szulgai. Stratton, C.W., Phelps, D.B., Reller, L.B. Am. J. Med. (1978)
- Effect of ethambutol on emergence of clarithromycin-resistant Mycobacterium avium complex in the beige mouse model. Bermudez, L.E., Nash, K.A., Petrofsky, M., Young, L.S., Inderlied, C.B. J. Infect. Dis. (1996)
- Susceptibilities of nontuberculosis mycobacterial species to amoxicillin-clavulanic acid alone and in combination with antimycobacterial agents. Utrup, L.J., Moore, T.D., Actor, P., Poupard, J.A. Antimicrob. Agents Chemother. (1995)
- Drug Therapy of Experimental Tuberculosis (TB): Improved Outcome by Combining SQ109, a New Diamine Antibiotic, with Existing TB Drugs. Nikonenko, B.V., Protopopova, M., Samala, R., Einck, L., Nacy, C.A. Antimicrob. Agents Chemother. (2007)
- Pharmacodynamics and pharmacokinetics of SQ109, a new diamine-based antitubercular drug. Jia, L., Tomaszewski, J.E., Hanrahan, C., Coward, L., Noker, P., Gorman, G., Nikonenko, B., Protopopova, M. Br. J. Pharmacol. (2005)