The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

District of Columbia

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of District of Columbia


High impact information on District of Columbia


Chemical compound and disease context of District of Columbia

  • In 1986, 51 cases of trichinosis were reported to CDC from 12 states and the District of Columbia. Thirty-six (71%) of these cases occurred in New Hampshire, Hawaii, Massachusetts, and Pennsylvania. Pennsylvania reported the largest number of cases, 15, or 29% of the total [11].
  • HIV/AIDS coverage in five African American newspapers (Amsterdam [New York] News, Oakland [California] Post, Washington [District of Columbia] Afro American, Atlanta Inquirer, and Chicago Citizen) was analyzed from 1991 to 1996 [12].

Biological context of District of Columbia


Associations of District of Columbia with chemical compounds

  • To understand better this phenomenon and other health-related behaviors, 28 states, the District of Columbia, and the Centers for Disease Control, Atlanta, surveyed over 22,000 US adults from 1981 through 1983 [15].
  • Sphingosine (SPN) has been claimed to be a negative modulator of transmembrane signaling through protein kinase C (PK-C) or some yet unidentified mechanism [for review see Y. A. Hannun and R. M. Bell, Science (Washington DC), 243: 500-507, 1989] [16].
  • Haefely's laboratory (Hoffman La Roche, Basel, Switzerland) and in the Laboratory of Preclinical Pharmacology (NIH, St. Elizabeths Hospital, Washington DC), that benzodiazepine action was mediated by a modulation of GABA action at GABA(A) receptors [17].
  • METHOD: Substance abuse surveys were completed every year for four years by predominantly black District of Columbia students, beginning when the students were in 4th/5th grade, and ending when they were in 7th/8th grade [18].
  • Angiotensin-converting enzyme inhibitors for cardiovascular therapy: recent advances at the Tenth World Congress of Cardiology Washington DC, September 14-19, 1986 [19].

Gene context of District of Columbia

  • Activated Ha-ras genes have been detected in 66% of spontaneous hepatocellular tumors in the B6C3F1 mouse [Reynolds et al., Science (Washington DC), 237:1309, 1988] [20].
  • The INK4A gene maps to the 9p21 region and was initially described [M. Serrano et al., Nature (Lond.), 366: 704-707, 1993; A. Kamb et al., Science (Washington DC), 264: 436-440, 1994] as encoding a 148-amino-acid protein termed p16 [21].
  • METHODS: In a Washington DC community-based study conducted in 1996, we tested 5318 Ashkenazi Jews for three BRCA1/2 founder mutations and identified 120 mutation carriers [22].
  • Structural studies on a congenital abnormal coagulation factor XII (Hageman factor), factor XII Washington D.C., have been performed to identify the defect responsible for its lack of procoagulant activity [23].
  • A complementary DNA of MRP has been cloned and based on the deduced sequence encodes a member of the superfamily of proteins which bind ATP and function in various transport processes [Cole et al., Science (Washington DC), 258: 1650, 1992] [24].

Analytical, diagnostic and therapeutic context of District of Columbia


  1. Quantitation of MYC gene expression in sporadic breast tumors with a real-time reverse transcription-PCR assay. Bièche, I., Laurendeau, I., Tozlu, S., Olivi, M., Vidaud, D., Lidereau, R., Vidaud, M. Cancer Res. (1999) [Pubmed]
  2. Gonorrhea in the United States, 1981-1996. Demographic and geographic trends. Fox, K.K., Whittington, W.L., Levine, W.C., Moran, J.S., Zaidi, A.A., Nakashima, A.K. Sexually transmitted diseases. (1998) [Pubmed]
  3. A handheld real time thermal cycler for bacterial pathogen detection. Higgins, J.A., Nasarabadi, S., Karns, J.S., Shelton, D.R., Cooper, M., Gbakima, A., Koopman, R.P. Biosensors & bioelectronics. (2003) [Pubmed]
  4. Implant therapy in partially edentulous, periodontally compromised patients: a review. Van der Weijden, G.A., van Bemmel, K.M., Renvert, S. Journal of clinical periodontology. (2005) [Pubmed]
  5. Registry to referral: using birth defects registries to refer infants and toddlers for early intervention services. Farel, A.M., Meyer, R.E., Hicken, M., Edmonds, L.D. Birth defects research. Part A, Clinical and molecular teratology. (2003) [Pubmed]
  6. Paying the physician's fee: Blue Shield and the reasonable charge. Delbanco, T.L., Meyers, K.C., Segal, E.A. N. Engl. J. Med. (1979) [Pubmed]
  7. Screening men for prostate and colorectal cancer in the United States: does practice reflect the evidence? Sirovich, B.E., Schwartz, L.M., Woloshin, S. JAMA (2003) [Pubmed]
  8. Prevalence of alcohol-impaired driving. Results from a national self-reported survey of health behaviors. Liu, S., Siegel, P.Z., Brewer, R.D., Mokdad, A.H., Sleet, D.A., Serdula, M. JAMA (1997) [Pubmed]
  9. The co-occurrence of DSM-IV alcohol abuse in DSM-IV alcohol dependence: results of the National Epidemiologic Survey on Alcohol and Related Conditions on heterogeneity that differ by population subgroup. Hasin, D.S., Grant, B.F. Arch. Gen. Psychiatry (2004) [Pubmed]
  10. The return of Cyclospora in 1997: another outbreak of cyclosporiasis in North America associated with imported raspberries. Cyclospora Working Group. Herwaldt, B.L., Beach, M.J. Ann. Intern. Med. (1999) [Pubmed]
  11. Trichinosis surveillance, United States, 1986. Bailey, T.M., Schantz, P.M. MMWR. CDC surveillance summaries : Morbidity and mortality weekly report. CDC surveillance summaries / Centers for Disease Control. (1988) [Pubmed]
  12. HIV/AIDS coverage in Black newspapers, 1991-1996: implications for health communication and health education. Pickle, K., Quinn, S.C., Brown, J.D. Journal of health communication. (2002) [Pubmed]
  13. The epidemiology of idiopathic dilated cardiomyopathy in women: the Washington DC Dilated Cardiomyopathy Study. Coughlin, S.S., Tefft, M.C. Epidemiology (Cambridge, Mass.) (1994) [Pubmed]
  14. Characteristics and distribution of nuclear medicine physicians. Shah, A.N., Carney, G.P. Investigative radiology. (1992) [Pubmed]
  15. Failure to use seat belts in the United States. The 1981-1983 Behavioral Risk Factor Surveys. Goldbaum, G.M., Remington, P.L., Powell, K.E., Hogelin, G.C., Gentry, E.M. JAMA (1986) [Pubmed]
  16. Cell membrane signaling as target in cancer therapy: inhibitory effect of N,N-dimethyl and N,N,N-trimethyl sphingosine derivatives on in vitro and in vivo growth of human tumor cells in nude mice. Endo, K., Igarashi, Y., Nisar, M., Zhou, Q.H., Hakomori, S. Cancer Res. (1991) [Pubmed]
  17. GABAA receptors and benzodiazepines: a role for dendritic resident subunit mRNAs. Costa, E., Auta, J., Grayson, D.R., Matsumoto, K., Pappas, G.D., Zhang, X., Guidotti, A. Neuropharmacology (2002) [Pubmed]
  18. Contradictory subject response in longitudinal research. Weinfurt, K.P., Bush, P.J. J. Stud. Alcohol (1996) [Pubmed]
  19. Angiotensin-converting enzyme inhibitors for cardiovascular therapy: recent advances at the Tenth World Congress of Cardiology Washington DC, September 14-19, 1986. Opie, L.H. Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy. (1987) [Pubmed]
  20. Activation of protooncogenes in spontaneously occurring non-liver tumors from C57BL/6 x C3H F1 mice. Candrian, U., You, M., Goodrow, T., Maronpot, R.R., Reynolds, S.H., Anderson, M.W. Cancer Res. (1991) [Pubmed]
  21. Overexpression of the cyclin-dependent kinase inhibitor p16 is associated with tumor recurrence in human prostate cancer. Lee, C.T., Capodieci, P., Osman, I., Fazzari, M., Ferrara, J., Scher, H.I., Cordon-Cardo, C. Clin. Cancer Res. (1999) [Pubmed]
  22. Breast cancer risk in Ashkenazi BRCA1/2 mutation carriers: effects of reproductive history. Hartge, P., Chatterjee, N., Wacholder, S., Brody, L.C., Tucker, M.A., Struewing, J.P. Epidemiology (Cambridge, Mass.) (2002) [Pubmed]
  23. Coagulation factor XII (Hageman factor) Washington D.C.: inactive factor XIIa results from Cys-571----Ser substitution. Miyata, T., Kawabata, S., Iwanaga, S., Takahashi, I., Alving, B., Saito, H. Proc. Natl. Acad. Sci. U.S.A. (1989) [Pubmed]
  24. The MRP gene associated with a non-P-glycoprotein multidrug resistance encodes a 190-kDa membrane bound glycoprotein. Krishnamachary, N., Center, M.S. Cancer Res. (1993) [Pubmed]
  25. The prevalence of hypovitaminosis D and secondary hyperparathyroidism in obese Black Americans. Yanoff, L.B., Parikh, S.J., Spitalnik, A., Denkinger, B., Sebring, N.G., Slaughter, P., McHugh, T., Remaley, A.T., Yanovski, J.A. Clin. Endocrinol. (Oxf) (2006) [Pubmed]
  26. The effectiveness of self-performed mechanical plaque control with triclosan containing dentifrices. Hioe, K.P., van der Weijden, G.A. International journal of dental hygiene. (2005) [Pubmed]
WikiGenes - Universities