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MeSH Review

Nobel Prize

 
 
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Disease relevance of Nobel Prize

  • The Nobel Prize in Medicine/Physiology for 1913 was awarded to Charles Richet, French physiologist, for studies of "anaphylaxis." The earliest articles on what was actually the original experimental induction of hypersensitivity were the result of collaborative studies of Paul Portier and Charles Richet [1].
  • Hormonal manipulation in the form of androgen-deprivation therapy for prostate cancer was introduced by Huggins and Hodges in 1941 and resulted in a Nobel Prize in 1966 [2].
  • In 1954, the Nobel Prize for Medicine was awarded to Drs John Enders, Thomas Weller, and Frederick Robbins for their watershed discovery that growth of poliomyelitis virus occurred in cultures of cells of extraneural origin, first reported in 1949 [3].
 

Psychiatry related information on Nobel Prize

 

High impact information on Nobel Prize

  • The announcement in October 1986 that the Nobel Prize for physiology or medicine was to be awarded to Rita Levi-Montalcini and Stanley Cohen for the discoveries of NGF and EGF, respectively, caused many to wonder why Viktor Hamburger (in whose laboratory the initial work was done) had not been included in the award [6].
  • The 1988 Nobel Prize for Physiology or Medicine [7].
  • Thus, Levi-Montalcini's work on NGF represents, as acknowledged by the Nobel Prize Assembly in its press release of 13 October 1986, "a fascinating example of how a skilled observer can create a concept out of apparent chaos" [8].
  • Agre, an American Society of Nephrology member, is the recipient of the 2003 Nobel Prize in Chemistry for his discovery of the aquaporin water channels [9].
  • The discovery of the adrenal steroid hormones was one of the momentous events of science and medicine in the 20th century, highlighted by the awarding of the Nobel Prize in Physiology or Medicine to Kendall, Reichstein and Hench in 1950 [10].
 

Biological context of Nobel Prize

 

Anatomical context of Nobel Prize

 

Associations of Nobel Prize with chemical compounds

  • Purine and sugar chemistry on solid phase--100 years after the Emil Fischer's Chemistry Nobel Prize 1902 [17].
  • Nitric oxide: from a mysterious labile factor to the molecule of the Nobel Prize. Recent progress in nitric oxide research [18].
  • To honour his discoveries, and to celebrate the 100 year since his Nobel Prize, we decided to write a short review article on the latest discoveries in the fields of purine/pyrimidine and sugar chemistry being performed on solid support [17].
  • The discovery and characterization of dopamine in the mammalian brain earned Dr. Arvid Carlsson the Nobel Prize in 2000 [19].
  • Prout in early 18th century of the presence of inorganic, hydrochloric acid in the stomach and by I.P. Pavlov at the end of 19th century of neuro-reflex stimulation of secretion of this acid that was awarded by Nobel prize in 1904 [20].
 

Gene context of Nobel Prize

 

Analytical, diagnostic and therapeutic context of Nobel Prize

References

  1. The ancestry of allergy: being an account of the original experimental induction of hypersensitivity recognizing the contribution of Paul Portier. May, C.D. J. Allergy Clin. Immunol. (1985) [Pubmed]
  2. Preventing and treating the complications of hormone therapy. Kumar, R.J., Barqawi, A., Crawford, E.D. Current urology reports. (2005) [Pubmed]
  3. Thomas Huckle Weller MD: Nobel Laureate and research pioneer in poliomyelitis, varicella-zoster virus, cytomegalovirus, rubella, and other infectious diseases. Ligon, B.L. Seminars in pediatric infectious diseases. (2002) [Pubmed]
  4. The 1973 Nobel Prize for Physiology or Medicine: recognition for behavioral science? Dewsbury, D.A. The American psychologist. (2003) [Pubmed]
  5. Three pioneers in the early history of neuroradiology: the Snyder lecture. Alper, M.G. Documenta ophthalmologica. Advances in ophthalmology. (1999) [Pubmed]
  6. Viktor Hamburger and Rita Levi-Montalcini: the path to the discovery of nerve growth factor. Cowan, W.M. Annu. Rev. Neurosci. (2001) [Pubmed]
  7. The 1988 Nobel Prize for Physiology or Medicine. Marx, J.L. Science (1988) [Pubmed]
  8. Rita Levi-Montalcini: the discovery of nerve growth factor and modern neurobiology. Aloe, L. Trends Cell Biol. (2004) [Pubmed]
  9. Peter Agre, 2003 Nobel Prize winner in chemistry. Knepper, M.A., Nielsen, S. J. Am. Soc. Nephrol. (2004) [Pubmed]
  10. Neonatal dexamethasone therapy: short- and long-term consequences. Raff, H. Trends Endocrinol. Metab. (2004) [Pubmed]
  11. Centenary Nobel Prize in Physiology or Medicine for the cell cycle. Royer, H.D. J. Mol. Med. (2001) [Pubmed]
  12. The Nobel Lectures in Immunology. The Nobel Prize for Physiology or Medicine, 1987. Somatic generation of immune diversity. Tonegawa, S. Scand. J. Immunol. (1993) [Pubmed]
  13. The Nobel Lectures in Immunology. The Nobel Prize for Physiology or Medicine, 1996. Cell mediated immunity in virus infections. Doherty, P.C. Scand. J. Immunol. (1997) [Pubmed]
  14. Renatus renatus: the Cartesian tradition in British neuroscience and the neurophilosophy of John Carew Eccles. Smith, C.U. Brain and cognition. (2001) [Pubmed]
  15. To err and win a nobel prize: Paul Boyer, ATP synthase and the emergence of bioenergetics. Allchin, D. Journal of the history of biology. (2002) [Pubmed]
  16. The Nobel Lectures in Immunology. The Nobel Prize for Physiology or Medicine, 1990. Bone marrow transplantation--past, present and future. Thomas, E.D. Scand. J. Immunol. (1994) [Pubmed]
  17. Purine and sugar chemistry on solid phase--100 years after the Emil Fischer's Chemistry Nobel Prize 1902. Franzén, R., Tois, J. Comb. Chem. High Throughput Screen. (2003) [Pubmed]
  18. Nitric oxide: from a mysterious labile factor to the molecule of the Nobel Prize. Recent progress in nitric oxide research. Xu, W.M., Liu, L.Z. Cell Res. (1998) [Pubmed]
  19. Partial dopamine agonists in the treatment of psychosis. Tamminga, C.A. Journal of neural transmission (Vienna, Austria : 1996) (2002) [Pubmed]
  20. From nerves and hormones to bacteria in the stomach; Nobel prize for achievements in gastrology during last century. Konturek, S.J., Konturek, P.C., Brzozowski, T., Konturek, J.W., Pawlik, W.W. J. Physiol. Pharmacol. (2005) [Pubmed]
  21. Renal water reabsorption: a physiologic retrospective in a molecular era. Schafer, J.A. Kidney Int. Suppl. (2004) [Pubmed]
  22. Nobel Prize winners in surgery. Part 2. Jain, K.M., Swan, K.G., Casey, K.F. The American surgeon. (1982) [Pubmed]
  23. The magnocellular neurons of the hypothalamo-neurohypophyseal system display remarkable neuropeptidergic phenotypes leading to novel insights in neuronal cell biology. van Leeuwen, F.W., Verwer, R.W., Spence, H., Evans, D.A., Burbach, J.P. Prog. Brain Res. (1998) [Pubmed]
  24. The Nobel Lectures in Immunology. Lecture for the Nobel Prize for Physiology or Medicine, 1980: Studies in histocompatibility. Snell, G.D. Scand. J. Immunol. (1992) [Pubmed]
  25. The Nobel Lectures in Immunology. The Nobel Prize for Physiology or Medicine, 1980. The major histocompatibility complex in man. Past, present, and future concepts. Dansset, J. Scand. J. Immunol. (1992) [Pubmed]
  26. The Nobel Lectures in Immunology. The Nobel Prize for Physiology or Medicine, 1996. Cellular immune recognition and the biological role of major transplantation antigens. Zinkernagel, R.M. Scand. J. Immunol. (1997) [Pubmed]
  27. The use of peptidomics in endocrine research. Clynen, E., De Loof, A., Schoofs, L. Gen. Comp. Endocrinol. (2003) [Pubmed]
  28. Rejuvenation in the early 20th century. Schultheiss, D., Denil, J., Jonas, U. Andrologia (1997) [Pubmed]
 
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