Chemical Compound Review:
BOF 4272 sodium7-[3-methoxy-4- (phenylsulfinyl)phen...
Synonyms:
- Metabolic pathways and pharmacokinetics of BOF-4272, a sulfoxide-containing drug, in the dog: in vivo and in vitro studies. Naito, S., Nishimura, M., Yoshitsugu, H., Nogawa, H. Biol. Pharm. Bull. (1999)
- Xanthine oxidase inhibition attenuates kupffer cell production of neutrophil chemoattractant following ischemia-reperfusion in rat liver. Matsumura, F., Yamaguchi, Y., Goto, M., Ichiguchi, O., Akizuki, E., Matsuda, T., Okabe, K., Liang, J., Ohshiro, H., Iwamoto, T., Yamada, S., Mori, K., Ogawa, M. Hepatology (1998)
- Xanthine oxidase inhibitors suppress testicular germ cell apoptosis induced by experimental cryptorchidism. Kumagai, A., Kodama, H., Kumagai, J., Fukuda, J., Kawamura, K., Tanikawa, H., Sato, N., Tanaka, T. Mol. Hum. Reprod. (2002)
- In vitro and in vivo studies on the stereoselective pharmacokinetics and biotransformation of an (S)-(-)- and (R)-(+)-pyrazolotriazine sulfoxide in the male rat. Naito, S., Nishimura, M. Xenobiotica (2002)
- Pharmacokinetics of BOF-4272, a xanthine oxidase inhibitor, after single intravenous or oral administration to male mice and rats. Naito, S., Nishimura, M., Nogawa, H. J. Pharm. Pharmacol. (1999)
- Evaluation of the pharmacological actions and pharmacokinetics of BOF-4272, a xanthine oxidase inhibitor, in mouse liver. Naito, S., Nishimura, M., Tamao, Y. J. Pharm. Pharmacol. (2000)
- Hepatic local disposition of a drug with high protein binding and high hepatic clearance using BOF-4272 as a model drug. Nishimura, M., Yamaoka, K., Naito, S., Nakagawa, T. Biol. Pharm. Bull. (1996)
- Enantioselective uptake of BOF-4272, a xanthine oxidase inhibitor with a chiral sulfoxide, by isolated rat hepatocytes. Naito, S., Nishimura, M. Yakugaku Zasshi (2001)
- Biotransformation of the xanthine oxidase inhibitor BOF-4272 and its metabolites in the liver and by the intestinal flora in rat. Naito, S., Nishimura, M. Xenobiotica (2000)
- Influence of albumin on enantioselective local disposition of BOF-4272, a xanthine oxidase inhibitor with chiral sulfoxide, in rat liver. Nishimura, M., Yamaoka, K., Naito, S., Nakagawa, T. Biol. Pharm. Bull. (1997)
- Biotransformation of BOF-4272, a sulfoxide-containing drug, in the cynomolgus monkey. Naito, S., Nishimura, M., Jin, Y. European journal of drug metabolism and pharmacokinetics. (1999)
- Local disposition of a new xanthine oxidase/xanthine dehydrogenase inhibitor, BOF-4272, in rat liver. Nishimura, M., Yamaoka, K., Yasui, H., Naito, S., Nakagawa, T. Biol. Pharm. Bull. (1994)
- A novel xanthine dehydrogenase inhibitor (BOF-4272). Sato, S., Tatsumi, K., Nishino, T. Adv. Exp. Med. Biol. (1991)
- Stereoselective pharmacokinetics of BOF-4272 racemate after oral administration to rats and dogs. Naito, S., Nishimura, M. Biol. Pharm. Bull. (2002)