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Gene Review

Cxcl1  -  chemokine (C-X-C motif) ligand 1

Rattus norvegicus

Synonyms: C-X-C motif chemokine 1, CINC-1, Cinc1, Cytokine-induced neutrophil chemoattractant 1, Gro, ...
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Disease relevance of Cxcl1


Psychiatry related information on Cxcl1


High impact information on Cxcl1


Chemical compound and disease context of Cxcl1


Biological context of Cxcl1


Anatomical context of Cxcl1


Associations of Cxcl1 with chemical compounds


Regulatory relationships of Cxcl1


Other interactions of Cxcl1


Analytical, diagnostic and therapeutic context of Cxcl1


  1. Cytokine-induced neutrophil chemoattractant mediates neutrophil influx in immune complex glomerulonephritis in rat. Wu, X., Wittwer, A.J., Carr, L.S., Crippes, B.A., DeLarco, J.E., Lefkowith, J.B. J. Clin. Invest. (1994) [Pubmed]
  2. Acute lung injury in endotoxemic rats is associated with sustained circulating IL-6 levels and intrapulmonary CINC activity and neutrophil recruitment--role of circulating TNF-alpha and IL-beta? Simons, R.K., Junger, W.G., Loomis, W.H., Hoyt, D.B. Shock (1996) [Pubmed]
  3. Cytokine-induced neutrophil chemoattractant 1 (CINC-1) mediates the sympathetic component of inflammatory mechanical hypersensitivitiy in rats. Lorenzetti, B.B., Veiga, F.H., Canetti, C.A., Poole, S., Cunha, F.Q., Ferreira, S.H. Eur. Cytokine Netw. (2002) [Pubmed]
  4. An inhibitory effect of cytokine-induced neutrophil chemoattractant on corticotropin-releasing factor-induced increase in locomotor activity. Terawaki, K., Koike, K., Yuzurihara, M., Kurauchi, K., Ishige, A., Sasaki, H., Murakami, K., Inoue, M. Brain Res. (2001) [Pubmed]
  5. The chemokine receptor CXCR2 controls positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. Tsai, H.H., Frost, E., To, V., Robinson, S., Ffrench-Constant, C., Geertman, R., Ransohoff, R.M., Miller, R.H. Cell (2002) [Pubmed]
  6. Dietary glycine prevents chemical-induced experimental colitis in the rat. Tsune, I., Ikejima, K., Hirose, M., Yoshikawa, M., Enomoto, N., Takei, Y., Sato, N. Gastroenterology (2003) [Pubmed]
  7. Cytokine-induced neutrophil chemoattractant in a rat model of lipopolysaccharide-induced acute lung injury. Yamasawa, H., Ishii, Y., Kitamura, S. Inflammation (1999) [Pubmed]
  8. Ranitidine reduces ischemia/reperfusion-induced liver injury in rats by inhibiting neutrophil activation. Okajima, K., Harada, N., Uchiba, M. J. Pharmacol. Exp. Ther. (2002) [Pubmed]
  9. Induction of cytokine-induced neutrophil chemoattractant in response to various stresses in rat C6 glioma cells. Uehara, T., Baba, I., Nomura, Y. Brain Res. (1998) [Pubmed]
  10. Chronic ethanol intoxication enhances the production of cytokine-induced neutrophil chemoattractant and macrophage inflammatory protein-2 by hepatocytes after human immunodeficiency virus-1 glycoprotein 120 vaccination. Bautista, A.P., Wang, E. Alcohol (2001) [Pubmed]
  11. Requirement for C-X-C chemokines (macrophage inflammatory protein-2 and cytokine-induced neutrophil chemoattractant) in IgG immune complex-induced lung injury. Shanley, T.P., Schmal, H., Warner, R.L., Schmid, E., Friedl, H.P., Ward, P.A. J. Immunol. (1997) [Pubmed]
  12. The neutrophil chemoattractant produced by the rat kidney epithelioid cell line NRK-52E is a protein related to the KC/gro protein. Watanabe, K., Konishi, K., Fujioka, M., Kinoshita, S., Nakagawa, H. J. Biol. Chem. (1989) [Pubmed]
  13. Cytokine-induced neutrophil chemoattractant-1 is released by the noninjured liver in a rat acute-phase model. Sheikh, N., Tron, K., Dudas, J., Ramadori, G. Lab. Invest. (2006) [Pubmed]
  14. Differential changes in the concentrations of cytokine-induced neutrophil chemoattractant (CINC)-1 and CINC-2 in exudate during rat lipopolysaccharide-induced inflammation. Shibata, F., Kato, H., Konishi, K., Okumora, A., Ochiai, H., Nakajima, K., Al-Mokdad, M., Nakagawa, H. Cytokine (1996) [Pubmed]
  15. TNF alpha and increased chemokine expression in rat lung after particle exposure. Driscoll, K.E., Hassenbein, D.G., Carter, J.M., Kunkel, S.L., Quinlan, T.R., Mossman, B.T. Toxicol. Lett. (1995) [Pubmed]
  16. Cytokine-induced neutrophil chemoattractant release from hepatocytes is modulated by Kupffer cells. Mawet, E., Shiratori, Y., Hikiba, Y., Takada, H., Yoshida, H., Okano, K., Komatsu, Y., Matsumura, M., Niwa, Y., Omata, M. Hepatology (1996) [Pubmed]
  17. Identification of cytokine-induced neutrophil chemoattractants (CINC), rat GRO/CINC-2 alpha and CINC-2 beta, produced by granulation tissue in culture: purification, complete amino acid sequences and characterization. Nakagawa, H., Komorita, N., Shibata, F., Ikesue, A., Konishi, K., Fujioka, M., Kato, H. Biochem. J. (1994) [Pubmed]
  18. Regulation of cytokine-induced neutrophil chemoattractant in rat bone marrow-derived macrophages by inflammatory mediators. Crippen, T.L., Klasing, K.C., Hyde, D.M. Pathobiology (1998) [Pubmed]
  19. Role of cytokine-induced neutrophil chemoattractant-2 (CINC-2) alpha in a rat model of chronic bronchopulmonary infections with Pseudomonas aeruginosa. Amano, H., Oishi, K., Sonoda, F., Senba, M., Wada, A., Nakagawa, H., Nagatake, T. Cytokine (2000) [Pubmed]
  20. Glucocorticoid-mediated gene suppression of rat cytokine-induced neutrophil chemoattractant CINC/gro, a member of the interleukin-8 family, through impairment of NF-kappa B activation. Ohtsuka, T., Kubota, A., Hirano, T., Watanabe, K., Yoshida, H., Tsurufuji, M., Iizuka, Y., Konishi, K., Tsurufuji, S. J. Biol. Chem. (1996) [Pubmed]
  21. Evidence that Toki-shakuyaku-san and its ingredients enhance the secretion of a cytokine-induced neutrophil chemoattractant (CINC/gro) in the ovulatory process. Irahara, M., Yasui, T., Tezuka, M., Ushigoe, K., Yamano, S., Kamada, M., Aono, T. Methods and findings in experimental and clinical pharmacology. (2000) [Pubmed]
  22. Cytokine-induced neutrophil chemoattractant production by primary rat alveolar type II cells. Crippen, T.L., Klasing, K.C., Hyde, D.M. Inflammation (1995) [Pubmed]
  23. Identification of a common receptor for three types of rat cytokine-induced neutrophil chemoattractants (CINCs). Shibata, F., Konishi, K., Nakagawa, H. Cytokine (2000) [Pubmed]
  24. Hepatocyte growth factor stimulates the induction of cytokine-induced neutrophil chemoattractant through the activation of NF-kappaB in rat hepatocytes. Kaibori, M., Yanagida, H., Nakanishi, H., Ozaki, T., Yoshida, H., Matsui, K., Hijikawa, T., Kamiyama, Y., Okumura, T. J. Surg. Res. (2006) [Pubmed]
  25. Regulatory effects of eotaxin on acute lung inflammatory injury. Guo, R.F., Lentsch, A.B., Warner, R.L., Huber-Lang, M., Sarma, J.V., Hlaing, T., Shi, M.M., Lukacs, N.W., Ward, P.A. J. Immunol. (2001) [Pubmed]
  26. Regulation of cytokine-induced neutrophil chemoattractant (CINC) mRNA production in cultured rat cells. Dolecki, G.J., Delarco, J.E. DNA Cell Biol. (1994) [Pubmed]
  27. Effect of cold-ischemia time on C-X-C chemokine expression and neutrophil accumulation in the graft liver after orthotopic liver transplantation in rats. Kataoka, M., Shimizu, H., Mitsuhashi, N., Ohtsuka, M., Wakabayashi, Y., Ito, H., Kimura, F., Nakagawa, K., Yoshidome, H., Shimizu, Y., Miyazaki, M. Transplantation (2002) [Pubmed]
  28. Selective transport of cytokine-induced neutrophil chemoattractant from the lung to the blood facilitates pulmonary neutrophil recruitment. Quinton, L.J., Nelson, S., Zhang, P., Boé, D.M., Happel, K.I., Pan, W., Bagby, G.J. Am. J. Physiol. Lung Cell Mol. Physiol. (2004) [Pubmed]
  29. Production and gene expression of IL-8-like cytokine GRO/CINC-1 in rat nasal mucosa. Himi, T., Yoshioka, I., Kataura, A. Acta Otolaryngol. (1997) [Pubmed]
  30. Involvement of platelet-activating factor in cytokine production and neutrophil activation after hepatic ischemia-reperfusion. Serizawa, A., Nakamura, S., Suzuki, n.u.l.l., Baba, S., Nakano, M. Hepatology (1996) [Pubmed]
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