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Chemical Compound Review

Cerebrosterin     (3S,8S,9S,10R,13R,14S,17R)- 17-[(2R,5S)-5...

Synonyms: Cerebrosterol, CHEMBL171804, SureCN200707, CPD-7239, AG-A-46280, ...
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Disease relevance of C13550


Psychiatry related information on C13550


High impact information on C13550


Biological context of C13550


Anatomical context of C13550


Gene context of C13550


Analytical, diagnostic and therapeutic context of C13550


  1. 24-hydroxycholesterol is a substrate for hepatic cholesterol 7alpha-hydroxylase (CYP7A). Norlin, M., Toll, A., Björkhem, I., Wikvall, K. J. Lipid Res. (2000) [Pubmed]
  2. Plasma cerebrosterol and magnetic resonance imaging measures in multiple sclerosis. Karrenbauer, V.D., Leoni, V., Lim, E.T., Giovannoni, G., Ingle, G.T., Sastre-Garriga, J., Thompson, A.J., Rashid, W., Davies, G., Miller, D.H., Björkhem, I., Masterman, T. Clinical neurology and neurosurgery. (2006) [Pubmed]
  3. Cholesterol in neurologic disorders of the elderly: stroke and Alzheimer's disease. Reiss, A.B., Siller, K.A., Rahman, M.M., Chan, E.S., Ghiso, J., de Leon, M.J. Neurobiol. Aging (2004) [Pubmed]
  4. Role of ABCG1 and ABCA1 in Regulation of Neuronal Cholesterol Efflux to Apolipoprotein E Discs and Suppression of Amyloid-beta Peptide Generation. Kim, W.S., Rahmanto, A.S., Kamili, A., Rye, K.A., Guillemin, G.J., Gelissen, I.C., Jessup, W., Hill, A.F., Garner, B. J. Biol. Chem. (2007) [Pubmed]
  5. Human sterol 27-hydroxylase (CYP27) overexpressor transgenic mouse model. Evidence against 27-hydroxycholesterol as a critical regulator of cholesterol homeostasis. Meir, K., Kitsberg, D., Alkalay, I., Szafer, F., Rosen, H., Shpitzen, S., Avi, L.B., Staels, B., Fievet, C., Meiner, V., Björkhem, I., Leitersdorf, E. J. Biol. Chem. (2002) [Pubmed]
  6. Expression cloning of an oxysterol 7alpha-hydroxylase selective for 24-hydroxycholesterol. Li-Hawkins, J., Lund, E.G., Bronson, A.D., Russell, D.W. J. Biol. Chem. (2000) [Pubmed]
  7. Oxysterol regulators of 3-hydroxy-3-methylglutaryl-CoA reductase in liver. Effect of dietary cholesterol. Saucier, S.E., Kandutsch, A.A., Gayen, A.K., Swahn, D.K., Spencer, T.A. J. Biol. Chem. (1989) [Pubmed]
  8. Lovastatin modulates increased cholesterol and oxysterol levels and has a neuroprotective effect on rat hippocampal neurons after kainate injury. He, X., Jenner, A.M., Ong, W.Y., Farooqui, A.A., Patel, S.C. J. Neuropathol. Exp. Neurol. (2006) [Pubmed]
  9. Rediscovery of cerebrosterol. Björkhem, I. Lipids (2007) [Pubmed]
  10. Neurotoxicity of 24-hydroxycholesterol, an important cholesterol elimination product of the brain, may be prevented by vitamin E and estradiol-17beta. Kölsch, H., Ludwig, M., Lütjohann, D., Rao, M.L. Journal of neural transmission (Vienna, Austria : 1996) (2001) [Pubmed]
  11. Metabolism of 27-, 25- and 24-hydroxycholesterol in rat glial cells and neurons. Zhang, J., Akwa, Y., el-Etr, M., Baulieu, E.E., Sjövall, J. Biochem. J. (1997) [Pubmed]
  12. Oxysterol 7alpha-hydroxylase (CYP39A1) in the ciliary nonpigmented epithelium of bovine eye. Ikeda, H., Ueda, M., Ikeda, M., Kobayashi, H., Honda, Y. Lab. Invest. (2003) [Pubmed]
  13. Profile of cholesterol-related sterols in aged amyloid precursor protein transgenic mouse brain. Lütjohann, D., Brzezinka, A., Barth, E., Abramowski, D., Staufenbiel, M., von Bergmann, K., Beyreuther, K., Multhaup, G., Bayer, T.A. J. Lipid Res. (2002) [Pubmed]
  14. High levels of (24S)-24-hydroxycholesterol 3-sulfate, 24-glucuronide in the serum and urine of children with severe cholestatic liver disease. Meng, L.J., Griffiths, W.J., Nazer, H., Yang, Y., Sjövall, J. J. Lipid Res. (1997) [Pubmed]
  15. Cholesterol homeostasis in human brain: turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation. Björkhem, I., Lütjohann, D., Diczfalusy, U., Ståhle, L., Ahlborg, G., Wahren, J. J. Lipid Res. (1998) [Pubmed]
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