Chemical Compound Review:
CHEMBL539495 6-(imidazol-1-ylmethyl)- 5,6,7,8...
Synonyms:
SureCN7301697, DP-1904, LS-94531, AC1L41PX, 97901-22-9, ...
This record was replaced with 65851.
- Improvement of renal function with a selective thromboxane A2 synthetase inhibitor, DP-1904, in lupus nephritis. Yoshida, T., Kameda, H., Ichikawa, Y., Tojo, T., Homma, M. J. Rheumatol. (1996)
- A thromboxane A2 synthase inhibitor, DP-1904, prevents rat renal injury. Masumura, H., Kunitada, S., Irie, K., Ashida, S., Abe, Y. Eur. J. Pharmacol. (1991)
- Effect of DP-1904, a thromboxane A2 synthetase inhibitor, on crescentic nephritis in rats. Nagao, T., Ito, M., Nagamatsu, T., Suzuki, Y. Eur. J. Pharmacol. (1994)
- Effect of DP-1904, a thromboxane A2 synthase inhibitor, on passive Heymann nephritis in rats. Nagao, T., Nagamatsu, T., Suzuki, Y. Eur. J. Pharmacol. (1996)
- Effect of DP-1904, a thromboxane synthetase inhibitor, on antigen- and spasmogen-induced bronchoconstriction in rodents. Takami, M., Tsukada, W. Eur. J. Pharmacol. (1999)
- In vitro responses to antigen stimulation: comparison between human lung parenchyma resected from asthmatic patients and non-asthmatic patients. Fukushima, C., Shimoda, T., Matsuse, H., Matsuo, N., Takao, A., Obase, Y., Asai, S., Ayabe, H., Kohno, S. Ann. Allergy Asthma Immunol. (1999)
- DP-1904, a specific inhibitor of thromboxane A2 synthesizing enzyme, suppresses ICAM-1 expression by stimulated vascular endothelial cells. Ishizuka, T., Suzuki, K., Kawakami, M., Kawaguchi, Y., Hidaka, T., Matsuki, Y., Nakamura, H. Eur. J. Pharmacol. (1994)
- A thromboxane A2 synthetase inhibitor retards hypertensive rat diabetic nephropathy. Masumura, H., Kunitada, S., Irie, K., Ashida, S., Abe, Y. Eur. J. Pharmacol. (1992)
- The pharmacokinetics and pharmacodynamics of a new thromboxane synthetase inhibitor, 6-(1-imidazolylmethyl)-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid (DP-1904), in man after single oral administration. Tanaka, M., Ono, K., Takegoshi, T., Shiozawa, T., Suzuki, T., Nii, S., Shibata, H. J. Pharm. Pharmacol. (1989)
- Pharmacokinetic-pharmacodynamic modelling of DP-1904, a novel thromboxane synthetase inhibitor in rabbits, based on an indirect response model. Zheng, N.X., Sato, H., Adachi, I., Horikoshi, I. European journal of drug metabolism and pharmacokinetics. (1996)
- Determination of the thromboxane synthetase inhibitor 6-(1-imidazolylmethyl)-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid (DP-1904) in human plasma and urine using solid-phase extraction and high-performance liquid chromatography. Tanaka, M., Ono, K., Takegoshi, T. J. Chromatogr. (1988)
- A novel thromboxane synthetase inhibitor, DP-1904, inhibits human blood eosinophil degranulation. Agrawal, D.K., Takami, M., Ono, S. Inflammation (1997)
- Effects of DP-1904, a thromboxane synthetase inhibitor, on the antigen-induced airway hyperresponsiveness and infiltration of inflammatory cells in guinea-pigs. Takami, M., Tsukada, W. Prostaglandins Leukot. Essent. Fatty Acids (1998)
- Thromboxane A2 synthase inhibitor, DP-1904, decreases TNF alpha secretion from monocytes and inhibits E-selectin and ICAM-1 expression on the endothelial cell surfaces. Kameda, H., Yoshida, T., Ichikawa, Y., Homma, M. Adv. Prostaglandin Thromboxane Leukot. Res. (1995)
- Identification of DP-1904 and its ester glucuronide in human urine and determination of their enantiomeric compositions by high-performance liquid chromatography with optical activity and ultraviolet detection. Tanaka, M., Ono, K., Hakusui, H., Takegoshi, T., Watanabe, Y., Kanao, M. Drug Metab. Dispos. (1990)
- Abnormal prostanoid metabolism in lupus nephritis and the effects of a thromboxane A2 synthetase inhibitor, DP-1904. Yoshida, T., Ichikawa, Y., Tojo, T., Homma, M. Lupus (1996)
- Correlative alteration of thromboxane A2 with antigen-induced bronchoconstriction and the role of platelets as a source of TXA2 synthesis in guinea pigs: effect of DP-1904, an inhibitor of thromboxane synthetase. Takami, M., Tsukada, W. Pharmacol. Res. (1998)