Gene Review:
ICAM1 - intercellular adhesion molecule 1
Homo sapiens
Synonyms:
BB2, CD54, ICAM-1, Intercellular adhesion molecule 1, Major group rhinovirus receptor, ...
Laippala,
Lockwood,
Jarrett,
Silvia Muro,
Poggi,
Ziemer,
Lewis,
Mills,
Mattila,
Goebel,
Hiltunen,
Mannermaa,
Messer,
Lehtimäki,
Soininen,
Walker,
Alafuzoff,
Tseng,
Negrini,
Raabe,
Tetzloff,
Scheule,
Rinne,
Caughman,
Simon,
Wendel,
Prevosto,
Massaro,
Zocchi,
Wataha,
Pierri,
Vladimir R. Muzykantov,
Saccardi,
Gobbi,
Heidenreich,
Sevim Barbasso Helmers,
Pernilla Englund,
Marianne Engström,
Erik Ahlin,
Maryam Fathi,
Sabina Janciauskiene,
Mikael Heimbürger,
Johan Rönnelid,
Ingrid E. Lundberg,
Edward H. Schuchman,
Krunkosky,
Röyttä,
Urbani,
- Large-scale association study identifies ICAM gene region as breast and prostate cancer susceptibility locus. Kammerer, S., Roth, R.B., Reneland, R., Marnellos, G., Hoyal, C.R., Markward, N.J., Ebner, F., Kiechle, M., Schwarz-Boeger, U., Griffiths, L.R., Ulbrich, C., Chrobok, K., Forster, G., Praetorius, G.M., Meyer, P., Rehbock, J., Cantor, C.R., Nelson, M.R., Braun, A. Cancer Res. (2004)
- Comparative analysis identifies conserved tumor necrosis factor receptor-associated factor 3 binding sites in the human and simian Epstein-Barr virus oncogene LMP1. Franken, M., Devergne, O., Rosenzweig, M., Annis, B., Kieff, E., Wang, F. J. Virol. (1996)
- Epidermotropism of T cells correlates with intercellular adhesion molecule (ICAM1) expression in human papillomavirus (HPV)-induced lesions. Viac, J., Chardonnet, Y., Euvrard, S., Schmitt, D. J. Pathol. (1992)
- ICAM-1, E-selectin, and TNF alpha expression in labial salivary glands of patients with rheumatoid vasculitis. Flipo, R.M., Cardon, T., Copin, M.C., Vandecandelaere, M., Duquesnoy, B., Janin, A. Ann. Rheum. Dis. (1997)
- ICAM gene cluster SNPs and prostate cancer risk in African Americans. Chen, H., Hernandez, W., Shriver, M.D., Ahaghotu, C.A., Kittles, R.A. Hum. Genet. (2006)
- Lysosomal enzyme delivery by ICAM-1-targeted nanocarriers bypassing glycosylation- and clathrin-dependent endocytosis. Muro, S., Schuchman, E.H., Muzykantov, V.R. Mol. Ther. (2006)
- Sera from anti-Jo-1-positive patients with polymyositis and interstitial lung disease induce expression of intercellular adhesion molecule 1 in human lung endothelial cells. Barbasso Helmers, S., Englund, P., Engström, M., Ahlin, E., Fathi, M., Janciauskiene, S., Heimbürger, M., Rönnelid, J., Lundberg, I.E. Arthritis Rheum. (2009)
- Vascular cell adhesion molecule 1 (CD106) on primary human articular chondrocytes: functional regulation of expression by cytokines and comparison with intercellular adhesion molecule 1 (CD54) and very late activation antigen 2. Kienzle, G., von Kempis, J. Arthritis Rheum. (1998)
- Crucial role of inhibitor of DNA binding/differentiation in the vascular endothelial growth factor-induced activation and angiogenic processes of human endothelial cells. Sakurai, D., Tsuchiya, N., Yamaguchi, A., Okaji, Y., Tsuno, N.H., Kobata, T., Takahashi, K., Tokunaga, K. J. Immunol. (2004)
- Acute psychological stress and exercise and changes in peripheral leukocyte adhesion molecule expression and density. Goebel, M.U., Mills, P.J. Psychosomatic medicine. (2000)
- Absence of association between an intercellular adhesion molecule 1 gene E469K polymorphism and Alzheimer's disease in Finnish patients. Mattila, K.M., Hiltunen, M., Rinne, J.O., Mannermaa, A., Röyttä, M., Alafuzoff, I., Laippala, P., Soininen, H., Lehtimäki, T. Neurosci. Lett. (2003)
- Chronic alcohol consumption increases serum levels of circulating endothelial cell/leucocyte adhesion molecules E-selectin and ICAM-1. Sacanella, E., Estruch, R., Badía, E., Fernández-Sola, J., Nicolás, J.M., Urbano-Márquez, A. Alcohol Alcohol. (1999)
- Endothelial-leukocyte adhesion molecules. Bevilacqua, M.P. Annu. Rev. Immunol. (1993)
- Structures of the alpha L I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation. Shimaoka, M., Xiao, T., Liu, J.H., Yang, Y., Dong, Y., Jun, C.D., McCormack, A., Zhang, R., Joachimiak, A., Takagi, J., Wang, J.H., Springer, T.A. Cell (2003)
- Fibrinogen mediates leukocyte adhesion to vascular endothelium through an ICAM-1-dependent pathway. Languino, L.R., Plescia, J., Duperray, A., Brian, A.A., Plow, E.F., Geltosky, J.E., Altieri, D.C. Cell (1993)
- The binding site on ICAM-1 for Plasmodium falciparum-infected erythrocytes overlaps, but is distinct from, the LFA-1-binding site. Berendt, A.R., McDowall, A., Craig, A.G., Bates, P.A., Sternberg, M.J., Marsh, K., Newbold, C.I., Hogg, N. Cell (1992)
- Chlamydial and human heat shock protein 60s activate human vascular endothelium, smooth muscle cells, and macrophages. Kol, A., Bourcier, T., Lichtman, A.H., Libby, P. J. Clin. Invest. (1999)
- Antiinflammatory effects of glucocorticoids in brain cells, independent of NF-kappa B. Bourke, E., Moynagh, P.N. J. Immunol. (1999)
- Activation of nuclear factor-kappa B and gene expression in human endothelial cells by the common haptens nickel and cobalt. Goebeler, M., Roth, J., Bröcker, E.B., Sorg, C., Schulze-Osthoff, K. J. Immunol. (1995)
- Distribution of immunoglobulin superfamily members ICAM-1, -2, -3, and the beta 2 integrin LFA-1 in multiple sclerosis lesions. Bö, L., Peterson, J.W., Mørk, S., Hoffman, P.A., Gallatin, W.M., Ransohoff, R.M., Trapp, B.D. J. Neuropathol. Exp. Neurol. (1996)
- Enhanced activation of rhesus T cells by vectors encoding a triad of costimulatory molecules (B7-1, ICAM-1, LFA-3). Shankar, P., Schlom, J., Hodge, J.W. Vaccine (2001)
- Comparison of cytolytic and proliferative activities of human gamma delta and alpha beta T cells from peripheral blood against various human tumor cell lines. Ensslin, A.S., Formby, B. J. Natl. Cancer Inst. (1991)
- Role of ICAM1 in invasion of human breast cancer cells. Rosette, C., Roth, R.B., Oeth, P., Braun, A., Kammerer, S., Ekblom, J., Denissenko, M.F. Carcinogenesis (2005)
- Expression of leucocyte adhesion molecules at the human blood-brain barrier (BBB). Rössler, K., Neuchrist, C., Kitz, K., Scheiner, O., Kraft, D., Lassmann, H. J. Neurosci. Res. (1992)
- The human intercellular adhesion molecule 3 (ICAM3) gene is located in the 19p13.2-p13.3 region, close to the ICAM1 gene. Bossy, D., Mattei, M.G., Simmons, D.L. Genomics (1994)
- Interaction between human NK cells and bone marrow stromal cells induces NK cell triggering: role of NKp30 and NKG2D receptors. Poggi, A., Prevosto, C., Massaro, A.M., Negrini, S., Urbani, S., Pierri, I., Saccardi, R., Gobbi, M., Zocchi, M.R. J. Immunol. (2005)
- Homocysteine is a risk factor for cerebral small vessel disease, acting via endothelial dysfunction. Hassan, A., Hunt, B.J., O'Sullivan, M., Bell, R., D'Souza, R., Jeffery, S., Bamford, J.M., Markus, H.S. Brain (2004)
- Haplotype-based association analysis of 56 functional candidate genes in the IBD6 locus on chromosome 19. Tello-Ruiz, M.K., Curley, C., DelMonte, T., Giallourakis, C., Kirby, A., Miller, K., Wild, G., Cohen, A., Langelier, D., Latiano, A., Wedemeyer, N., Lander, E., Schreiber, S., Annese, V., Daly, M.J., Rioux, J.D. Eur. J. Hum. Genet. (2006)
- Inhibition of adhesion molecule expression on human venous endothelial cells by non-viral siRNA transfection. Walker, T., Wendel, H.P., Tetzloff, L., Raabe, C., Heidenreich, O., Simon, P., Scheule, A.M., Ziemer, G. J. Cell. Mol. Med. (2007)
- Effect of vascular stent alloys on expression of cellular adhesion molecules by endothelial cells. Messer, R.L., Wataha, J.C., Lewis, J.B., Lockwood, P.E., Caughman, G.B., Tseng, W.Y. Journal of long-term effects of medical implants. (2005)
- The pathobiology of bronchial asthma. Arm, J.P., Lee, T.H. Adv. Immunol. (1992)
- Lymphocyte function-associated antigen-1 binding residues in intercellular adhesion molecule-2 (ICAM-2) and the integrin binding surface in the ICAM subfamily. Casasnovas, J.M., Pieroni, C., Springer, T.A. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Interleukin-4 induces homotypic aggregation of human mast cells by promoting LFA-1/ICAM-1 adhesion molecules. Toru, H., Kinashi, T., Ra, C., Nonoyama, S., Yata, J., Nakahata, T. Blood (1997)
- Adhesion of activated T lymphocytes to vascular smooth muscle cells and dermal fibroblasts is mediated by beta 1- and beta 2-integrins. Stemme, S., Patarroyo, M., Hansson, G.K. Scand. J. Immunol. (1992)
- Regulation of adhesion molecule expression in Kaposi's sarcoma cells. Yang, J., Xu, Y., Zhu, C., Hagan, M.K., Lawley, T., Offermann, M.K. J. Immunol. (1994)
- Epitope mapping of monoclonal antibody to integrin alphaL beta2 hybrid domain suggests different requirements of affinity states for intercellular adhesion molecules (ICAM)-1 and ICAM-3 binding. Tang, R.H., Tng, E., Law, S.K., Tan, S.M. J. Biol. Chem. (2005)
- Selective regulation of MAP kinases and chemokine expression after ligation of ICAM-1 on human airway epithelial cells. Krunkosky, T.M., Jarrett, C.L. Respir. Res. (2006)
- E-selectin and interleukin-2 receptor alpha-chain expression in alopecia universalis. Rilo, H.L., Carroll, P.B., Subbotin, V., Johnson, N., Van Thiel, D.H., Thomson, A.W. Acta Derm. Venereol. (1994)
- Levamisole effects on major histocompatibility complex and adhesion molecule expression and on myeloid cell adhesion to human colon tumor cell lines. Kimball, E.S., Fisher, M.C. J. Natl. Cancer Inst. (1996)
- Production of chemokines, interleukin-8 and monocyte chemoattractant protein-1, during monocyte: endothelial cell interactions. Lukacs, N.W., Strieter, R.M., Elner, V., Evanoff, H.L., Burdick, M.D., Kunkel, S.L. Blood (1995)
- Differential expression and release of CD54 induced by cytokines. Mickelson, J.K., Kukielka, G., Bravenec, J.S., Mainolfi, E., Rothlein, R., Hawkins, H.K., Kelly, J.H., Smith, C.W. Hepatology (1995)
- Filamin B mediates ICAM-1-driven leukocyte transendothelial migration. Kanters, E., van Rijssel, J., Hensbergen, P.J., Hondius, D., Mul, F.P., Deelder, A.M., Sonnenberg, A., van Buul, J.D., Hordijk, P.L. J. Biol. Chem. (2008)
- Molecular cloning of ICAM-3, a third ligand for LFA-1, constitutively expressed on resting leukocytes. Fawcett, J., Holness, C.L., Needham, L.A., Turley, H., Gatter, K.C., Mason, D.Y., Simmons, D.L. Nature (1992)
- Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-alpha production in rheumatoid arthritis. McInnes, I.B., Leung, B.P., Sturrock, R.D., Field, M., Liew, F.Y. Nat. Med. (1997)
- Activation and homologous desensitization of human endothelial cells by CD40 ligand, tumor necrosis factor, and interleukin 1. Karmann, K., Min, W., Fanslow, W.C., Pober, J.S. J. Exp. Med. (1996)
- Human vascular endothelial cell adhesion receptors for Plasmodium falciparum-infected erythrocytes: roles for endothelial leukocyte adhesion molecule 1 and vascular cell adhesion molecule 1. Ockenhouse, C.F., Tegoshi, T., Maeno, Y., Benjamin, C., Ho, M., Kan, K.E., Thway, Y., Win, K., Aikawa, M., Lobb, R.R. J. Exp. Med. (1992)
- Cloning and expression of intercellular adhesion molecule 3 reveals strong homology to other immunoglobulin family counter-receptors for lymphocyte function-associated antigen 1. de Fougerolles, A.R., Klickstein, L.B., Springer, T.A. J. Exp. Med. (1993)
- Endothelial cell cortactin coordinates intercellular adhesion molecule-1 clustering and actin cytoskeleton remodeling during polymorphonuclear leukocyte adhesion and transmigration. Yang, L., Kowalski, J.R., Yacono, P., Bajmoczi, M., Shaw, S.K., Froio, R.M., Golan, D.E., Thomas, S.M., Luscinskas, F.W. J. Immunol. (2006)
- Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cells. Nagel, T., Resnick, N., Atkinson, W.J., Dewey, C.F., Gimbrone, M.A. J. Clin. Invest. (1994)
- Association of intercellular adhesion molecule 1 with the multichain high-affinity interleukin 2 receptor. Burton, J., Goldman, C.K., Rao, P., Moos, M., Waldmann, T.A. Proc. Natl. Acad. Sci. U.S.A. (1990)