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Chemical Compound Review

EPNP     2-[(4- nitrophenoxy)methyl]oxirane

Synonyms: CHEBI:508, CHEMBL33775, NSC-1733, CCRIS 6429, AG-C-46678, ...
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Disease relevance of Glycidylnitrophenyl ether


High impact information on Glycidylnitrophenyl ether


Biological context of Glycidylnitrophenyl ether


Anatomical context of Glycidylnitrophenyl ether


Associations of Glycidylnitrophenyl ether with other chemical compounds


Gene context of Glycidylnitrophenyl ether


Analytical, diagnostic and therapeutic context of Glycidylnitrophenyl ether


  1. In vitro characterization of nonpeptide irreversible inhibitors of HIV proteases. Salto, R., Babé, L.M., Li, J., Rosé, J.R., Yu, Z., Burlingame, A., De Voss, J.J., Sui, Z., Ortiz de Montellano, P., Craik, C.S. J. Biol. Chem. (1994) [Pubmed]
  2. Structure of the protease from simian immunodeficiency virus: complex with an irreversible nonpeptide inhibitor. Rose, R.B., Rosé, J.R., Salto, R., Craik, C.S., Stroud, R.M. Biochemistry (1993) [Pubmed]
  3. Base-pair mutations caused by six aliphatic epoxides in Salmonella typhimurium TA100, TA104, TA4001, and TA4006. Einistö, P., Hooberman, B.H., Sinsheimer, J.E. Environ. Mol. Mutagen. (1993) [Pubmed]
  4. Dichloromethane mediated in vivo selection and functional characterization of rat glutathione S-transferase theta 1-1 variants. Gisi, D., Maillard, J., Flanagan, J.U., Rossjohn, J., Chelvanayagam, G., Board, P.G., Parker, M.W., Leisinger, T., Vuilleumier, S. Eur. J. Biochem. (2001) [Pubmed]
  5. Functional characterization and crystal structure of the C215D mutant of protein-tyrosine phosphatase-1B. Romsicki, Y., Scapin, G., Beaulieu-Audy, V., Patel, S., Becker, J.W., Kennedy, B.P., Asante-Appiah, E. J. Biol. Chem. (2003) [Pubmed]
  6. Tyr115, gln165 and trp209 contribute to the 1, 2-epoxy-3-(p-nitrophenoxy)propane-conjugating activity of glutathione S-transferase cGSTM1-1. Chern, M.K., Wu, T.C., Hsieh, C.H., Chou, C.C., Liu, L.F., Kuan, I.C., Yeh, Y.H., Hsiao, C.D., Tam, M.F. J. Mol. Biol. (2000) [Pubmed]
  7. Glutathione S-transferases from the white-rot fungus, Phanerochaete chrysosporium. Dowd, C.A., Buckley, C.M., Sheehan, D. Biochem. J. (1997) [Pubmed]
  8. Purification and biochemical characterization of recombinant simian immunodeficiency virus protease and comparison to human immunodeficiency virus type 1 protease. Grant, S.K., Deckman, I.C., Minnich, M.D., Culp, J., Franklin, S., Dreyer, G.B., Tomaszek, T.A., Debouck, C., Meek, T.D. Biochemistry (1991) [Pubmed]
  9. The effect of acid proteinase inhibitors on chicken pepsin. Llewellin, J.M., Green, M.L. Biochem. J. (1975) [Pubmed]
  10. Activation and inactivation of carcinogenic dihaloalkanes and other compounds by glutathione S-transferase 5-5 in Salmonella typhimurium tester strain NM5004. Shimada, T., Yamazaki, H., Oda, Y., Hiratsuka, A., Watabe, T., Guengerich, F.P. Chem. Res. Toxicol. (1996) [Pubmed]
  11. Activities of enzymes associated with the metabolism of glutathione in fetal rat liver and placenta. Di Ilio, C., Del Boccio, G., Casalone, E., Aceto, A., Sacchetta, P. Biol. Neonate (1986) [Pubmed]
  12. Species differences in the glutathione transferase GSTT1-1 activity towards the model substrates methyl chloride and dichloromethane in liver and kidney. Thier, R., Wiebel, F.A., Hinkel, A., Burger, A., Brüning, T., Morgenroth, K., Senge, T., Wilhelm, M., Schulz, T.G. Arch. Toxicol. (1998) [Pubmed]
  13. Effects of acid proteinase inhibitors on human neutrophil chemotaxis and lysosomal enzyme release. II. Bromphenacyl bromide and 1,2-epoxy-3-(p-nitrophenoxy)propane. Ackerman, S.K., Matter, L., Douglas, S.D. Clin. Immunol. Immunopathol. (1983) [Pubmed]
  14. Glutathione transferase theta 1-1-dependent metabolism of the water disinfection byproduct bromodichloromethane. Ross, M.K., Pegram, R.A. Chem. Res. Toxicol. (2003) [Pubmed]
  15. Autocatalytic cleavage of Clostridium difficile toxin B. Reineke, J., Tenzer, S., Rupnik, M., Koschinski, A., Hasselmayer, O., Schrattenholz, A., Schild, H., von Eichel-Streiber, C. Nature (2007) [Pubmed]
  16. Kinetic characterization of recombinant human glutathione transferase T1-1, a polymorphic detoxication enzyme. Jemth, P., Mannervik, B. Arch. Biochem. Biophys. (1997) [Pubmed]
  17. Photoaffinity reagents for use with pepsin and other carboxyl proteases. Hixson, S.H., Hurwitz, J.L., Langridge, K.J., Nichols, D.C., Provost, K.M., Wolff, A.M. Biochem. Biophys. Res. Commun. (1983) [Pubmed]
  18. Effects of model traumatic injury on hepatic drug metabolism in the rat. VI. Major detoxification/toxification pathways. Griffeth, L.K., Rosen, G.M., Rauchman, E.J. Drug Metab. Dispos. (1987) [Pubmed]
  19. Enantioselective detoxication of optical isomers of glycidyl ethers. Chen, R., Nguyen, P., You, Z., Sinsheimer, J.E. Chirality. (1993) [Pubmed]
  20. Epoxide hydrolase activity in human blood mononuclear leukocytes: individual differences in native and mitogen-stimulated cells. Bernardini, S., Norppa, H., Elovaara, E. Mutat. Res. (1999) [Pubmed]
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