Gene Review:
Ephx2 - epoxide hydrolase 2, cytoplasmic
Rattus norvegicus
Synonyms:
Bifunctional epoxide hydrolase 2
- Isolation and characterization of a cDNA encoding rat liver cytosolic epoxide hydrolase and its functional expression in Escherichia coli. Knehr, M., Thomas, H., Arand, M., Gebel, T., Zeller, H.D., Oesch, F. J. Biol. Chem. (1993)
- Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension. Imig, J.D., Zhao, X., Capdevila, J.H., Morisseau, C., Hammock, B.D. Hypertension (2002)
- Attenuation of tobacco smoke-induced lung inflammation by treatment with a soluble epoxide hydrolase inhibitor. Smith, K.R., Pinkerton, K.E., Watanabe, T., Pedersen, T.L., Ma, S.J., Hammock, B.D. Proc. Natl. Acad. Sci. U.S.A. (2005)
- The effects of varying the expression of a neutral cholesteryl ester hydrolase on the turnover of cholesteryl ester in rat hepatoma cells. Zolfaghari, R., Glick, J.M., Fisher, E.A. J. Biol. Chem. (1993)
- Cholesterol metabolism in rat adrenal gland during reversible endotoxic shock. Abarca, S., García, R. Eur. J. Biochem. (1993)
- The N-terminal domain of mammalian soluble epoxide hydrolase is a phosphatase. Cronin, A., Mowbray, S., Dürk, H., Homburg, S., Fleming, I., Fisslthaler, B., Oesch, F., Arand, M. Proc. Natl. Acad. Sci. U.S.A. (2003)
- Expression in Xenopus oocytes of rat liver mRNA coding for a bile salt-dependent cholesteryl ester hydrolase. Zolfaghari, R., Harrison, E.H., Ross, A.C., Fisher, E.A. Proc. Natl. Acad. Sci. U.S.A. (1989)
- Age- and gender-related changes in the hepatic metabolism of 2-methylpropene and relationship to epoxide metabolizing enzymes. Cornet, M., Mertens, K., Callaerts, A., Sonck, W., Vercruysse, A., Rogiers, V. Mech. Ageing Dev. (1994)
- Difference of gene expression profiles in spontaneous hypertensive rats and Wistar-Kyoto rats from two sources. Okuda, T., Sumiya, T., Iwai, N., Miyata, T. Biochem. Biophys. Res. Commun. (2002)
- Polymorphism in soluble epoxide hydrolase and blood pressure in spontaneously hypertensive rats. Fornage, M., Hinojos, C.A., Nurowska, B.W., Boerwinkle, E., Hammock, B.D., Morisseau, C.H., Doris, P.A. Hypertension (2002)
- Coordinate induction of peroxisomal beta-oxidation activity and cytosolic epoxide hydrolase activity. Oesch, F., Schladt, L. Pharmacol. Ther. (1987)
- Regulation of the rat neutral cytosolic cholesteryl ester hydrolase promoter by hormones and sterols: a role for nuclear factor-Y in the sterol-mediated response. Natarajan, R., Ghosh, S., Grogan, W.M. J. Lipid Res. (1999)
- Testicular temperature-labile cholesteryl ester hydrolase. Relationship to isoenzymes from other tissues, correlation with spermatogenesis, and inhibition by physiological concentrations of divalent cations. Wee, S., Grogan, W.M. J. Biol. Chem. (1993)
- Analysis of microsomal cholesteryl ester hydrolases by radiation inactivation. Harrison, E.H., Rojas, C.J., Gad, M.Z., Kempner, E.S. J. Biol. Chem. (1993)
- Structure and organization of the microsomal xenobiotic epoxide hydrolase gene. Falany, C.N., McQuiddy, P., Kasper, C.B. J. Biol. Chem. (1987)
- Microsomal and cytosolic epoxide hydrolases, the peroxisomal fatty acid beta-oxidation system and catalase. Activities, distribution and induction in rat liver parenchymal and non-parenchymal cells. Steinberg, P., Schladt, L., Dienes, H.P., Timms, C., Oesch, F. Eur. J. Biochem. (1988)
- Xenobiotic metabolizing enzyme activities and viability are well preserved in EDTA-isolated rat liver parenchymal cells after cryopreservation. Diener, B., Abdel-Latif, H., Arand, M., Oesch, F. Toxicol. Appl. Pharmacol. (1995)
- Determination of DNA single strand breaks and selective DNA amplification by N-nitrodimethylamine and analogs, and estimation of the indicator cells' metabolic capacities. Frei, E., Pool, B.L., Glatt, H.R., Gemperlein-Mertes, I., Oesch, F., Schlehofer, J.R., Schmezer, P., Weber, H., Wiessler, M. J. Cancer Res. Clin. Oncol. (1986)
- Protein expression changes in the Sprague Dawley rat liver proteome following administration of peroxisome proliferator activated receptor alpha and gamma ligands. White, I.R., Man, W.J., Bryant, D., Bugelski, P., Camilleri, P., Cutler, P., Hayes, W., Holbrook, J.D., Kramer, K., Lord, P.G., Wood, J. Proteomics (2003)
- An impaired peroxisomal targeting sequence leading to an unusual bicompartmental distribution of cytosolic epoxide hydrolase. Arand, M., Knehr, M., Thomas, H., Zeller, H.D., Oesch, F. FEBS Lett. (1991)
- Molecular cloning and expression of rat lung carboxylesterase and its potential role in the detoxification of organophosphorus compounds. Wallace, T.J., Ghosh, S., McLean Grogan, W. Am. J. Respir. Cell Mol. Biol. (1999)
- Rapid three-step purification of a hepatic neutral cholesteryl ester hydrolase which is not the pancreatic enzyme. Ghosh, S., Grogan, W.M. Lipids (1991)