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Chemical Compound Review

Erlosamide     (2R)-2-acetamido-N-benzyl-3- methoxy...

Synonyms: Lacosamide, Vimpat, Harkoseride, SPM-927, SPM-929, ...
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Disease relevance of SPM 927


Psychiatry related information on SPM 927


High impact information on SPM 927


Chemical compound and disease context of SPM 927


Biological context of SPM 927


Analytical, diagnostic and therapeutic context of SPM 927


  1. Antinociceptive efficacy of lacosamide in a rat model for painful diabetic neuropathy. Beyreuther, B., Callizot, N., Stöhr, T. Eur. J. Pharmacol. (2006) [Pubmed]
  2. Lacosamide, a new anti-epileptic, alleviates neuropathic pain-like behaviors in rat models of spinal cord or trigeminal nerve injury. Hao, J.X., St??hr, T., Selve, N., Wiesenfeld-Hallin, Z., Xu, X.J. Eur. J. Pharmacol. (2006) [Pubmed]
  3. Lacosamide in painful diabetic peripheral neuropathy: a phase 2 double-blind placebo-controlled study. Rauck, R.L., Shaibani, A., Biton, V., Simpson, J., Koch, B. The Clinical journal of pain (2007) [Pubmed]
  4. Lacosamide displays potent antinociceptive effects in animal models for inflammatory pain. Stöhr, T., Krause, E., Selve, N. European journal of pain (London, England) (2006) [Pubmed]
  5. Seeking a mechanism of action for the novel anticonvulsant lacosamide. Errington, A.C., Coyne, L., Stöhr, T., Selve, N., Lees, G. Neuropharmacology (2006) [Pubmed]
  6. Effects of the novel antiepileptic drug lacosamide on the development of amygdala kindling in rats. Brandt, C., Heile, A., Potschka, H., Stoehr, T., L??scher, W. Epilepsia (2006) [Pubmed]
  7. Stereoselective effects of the novel anticonvulsant lacosamide against 4-AP induced epileptiform activity in rat visual cortex in vitro. Lees, G., Stöhr, T., Errington, A.C. Neuropharmacology (2006) [Pubmed]
  8. Antinociceptive efficacy of lacosamide in the monosodium iodoacetate rat model for osteoarthritis pain. Beyreuther, B., Callizot, N., Stöhr, T. Arthritis Res. Ther. (2007) [Pubmed]
  9. The novel antiepileptic drug lacosamide blocks behavioral and brain metabolic manifestations of seizure activity in the 6 Hz psychomotor seizure model. Duncan, G.E., Kohn, H. Epilepsy Res. (2005) [Pubmed]
  10. Lacosamide. Doty, P., Rudd, G.D., Stoehr, T., Thomas, D. Neurotherapeutics (2007) [Pubmed]
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