Chemical Compound Review:
Ledakrin 3-dimethylammoniopropyl-(1- nitroacridin-9...
Synonyms:
Ledacrine, DwLIP-GCGRrx, Nitracrine HCl, CCRIS 9297, C-283, ...
This record was replaced with 20628.
- Behavior of some biochemical components of blood of patients with ovarian carcinoma during Ledakrin treatment. Dobryszcka, W. Materia medica Polona. Polish journal of medicine and pharmacy. (1976)
- Inhibition of RNA polymerase B activity in normal and regenerating rat liver after administration of 9-aminoacridine. Krawczyk, Z. Acta Biochim. Pol. (1982)
- Comparative study of mutagenic, inductive and transforming activities of ledakrin. Gajcy, H., Chłopkiewicz, B., Koziorowska, J. Polish journal of pharmacology and pharmacy. (1979)
- Results of combined treatment withlung tissue resection and simultaneous administration of Ledakrin in bronchial carcinoma. Rogalski, E., Domagala, J., Kolodziej, J. Materia medica Polona. Polish journal of medicine and pharmacy. (1976)
- High-resolution autoradiographic study on the presence of chromatin structures within interchromatin granule conglomerations. Gruca, S., Krzyzowska-Gruca, S., Zborek, A. Acta Histochem. (1981)
- Products of metabolic activation of the antitumor drug ledakrin (nitracrine) in vitro. Gorlewska, K., Mazerska, Z., Sowiński, P., Konopa, J. Chem. Res. Toxicol. (2001)
- Distribution of interchromatin granules in nuclear matrices obtained from nuclei exhibiting different degree of chromatin condensation. Krzyzowska-Gruca, S., Zborek, A., Gruca, S. Cell Tissue Res. (1983)
- In vitro DNA crosslinking by Ledakrin, an antitumor derivative of 1-nitro-9-aminoacridine. Bartoszek, A., Dackiewicz, P., Składanowski, A., Konopa, J. Chem. Biol. Interact. (1997)
- Effects of ledakrin on DNA and cell cycle in HeLa S3 cells. Woynarowski, J.M., Konopa, J. Drugs under experimental and clinical research. (1986)
- DNA damage in HeLa s3 cells by an antitumor drug Ledakrin and other antitumor 1-nitro-9-aminoacridines. Woynarowski, J.M., Bartoszek, A., Konopa, J. Chem. Biol. Interact. (1984)
- The mode of action of cytotoxic and antitumor 1-nitroacridines. III. In vivo interstrand cross-linking of DNA of mammalian or bacterial cells by 1-nitroacridines. Konopa, J., Pawlak, J.W., Pawlak, K. Chem. Biol. Interact. (1983)
- The mechanism of inhibition of DNA replication in HeLa S3 cells by the antitumor drug Ledakrin and other antitumor 1-nitro-9-aminoacridines. Woynarowski, J.M., Bartoszek, A. Biochim. Biophys. Acta (1985)
- Sodium transport across isolated epithelial structures in vitro--Ledakrin in the liposomes as a moderator of the bioelectric activity of frog skin. Rakowski, W., Knapowski, J. Acta physiologica Polonica. (1983)
- Early effect of ledakrin -- a nitro-derivative of acridine -- on cell membrane. Popowicz, P., Podsiadło, H., Knapowski, J. Acta physiologica Polonica. (1980)
- Blood serum peptidases in patients with ovarian carcinoma treated with Ledakrin. Warwas, M., Narczeuska, B., Dobryszycka, W. Arch. Immunol. Ther. Exp. (Warsz.) (1977)
- The mode of action of cytotoxic and antitumor 1-nitroacridines. II. In vivo enzyme-mediated covalent binding of a 1-nitroacridine derivative, Ledakrin or Nitracrine, with dna and other macromolecules of mammalian or bacterial cells. Pawlak, J.W., Pawlak, K., Konopa, J. Chem. Biol. Interact. (1983)
- Analysis of the cell cycle in the root meristem of Allium cepa under the influence of ledakrin. Antosiewicz, D. Folia Histochem. Cytobiol. (1990)