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Chemical Compound Review

Homospermidine     N-(4-aminobutyl)butane-1,4- diamine

Synonyms: CHEMBL36119, AG-K-86556, CHEBI:16554, KST-1B4436, CTK1D7246, ...
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Disease relevance of C06366


High impact information on C06366


Chemical compound and disease context of C06366


Biological context of C06366


Anatomical context of C06366


Associations of C06366 with other chemical compounds


Gene context of C06366


Analytical, diagnostic and therapeutic context of C06366


  1. Cloning and expression of a cDNA encoding homospermidine synthase from Senecio vulgaris (Asteraceae) in Escherichia coli. Kaiser, A. Plant J. (1999) [Pubmed]
  2. Chlorella virus PBCV-1 encodes a functional homospermidine synthase. Kaiser, A., Vollmert, M., Tholl, D., Graves, M.V., Gurnon, J.R., Xing, W., Lisec, A.D., Nickerson, K.W., Van Etten, J.L. Virology (1999) [Pubmed]
  3. Occurrence of sym-homospermidine as the major polyamine in nitrogen-fixing cyanobacteria. Hamana, K., Miyagawa, K., Matsuzaki, S. Biochem. Biophys. Res. Commun. (1983) [Pubmed]
  4. Polyamines as a chemotaxonomic marker in bacterial systematics. Hamana, K., Matsuzaki, S. Crit. Rev. Microbiol. (1992) [Pubmed]
  5. Purification and characterization of homospermidine synthase in Acinetobacter tartarogenes ATCC 31105. Yamamoto, S., Nagata, S., Kusaba, K. J. Biochem. (1993) [Pubmed]
  6. Reversal of the deoxyhypusine synthesis reaction. Generation of spermidine or homospermidine from deoxyhypusine by deoxyhypusine synthase. Park, J.H., Wolff, E.C., Folk, J.E., Park, M.H. J. Biol. Chem. (2003) [Pubmed]
  7. Molecular evolution by change of function. Alkaloid-specific homospermidine synthase retained all properties of deoxyhypusine synthase except binding the eIF5A precursor protein. Ober, D., Harms, R., Witte, L., Hartmann, T. J. Biol. Chem. (2003) [Pubmed]
  8. Reaffirmation that metabolism of polyamines by bovine plasma amine oxidase occurs strictly at the primary amino termini. Lee, Y., Sayre, L.M. J. Biol. Chem. (1998) [Pubmed]
  9. A new polyamine 4-aminobutylcadaverine. Occurrence and its biosynthesis in root nodules of adzuki bean plant Vigna angularis. Fujihara, S., Abe, H., Yoneyama, T. J. Biol. Chem. (1995) [Pubmed]
  10. Structural specificity of the triamines sym-homospermidine and aminopropylcadaverine in stimulating growth of spermidine auxotrophs of Escherichia coli. Linderoth, N., Morris, D.R. Biochem. Biophys. Res. Commun. (1983) [Pubmed]
  11. Polyamine analysis for chemotaxonomy of thermophilic eubacteria: Polyamine distribution profiles within the orders Aquificales, Thermotogales, Thermodesulfobacteriales, Thermales, Thermoanaerobacteriales, Clostridiales and Bacillales. Hosoya, R., Hamana, K., Niitsu, M., Itoh, T. J. Gen. Appl. Microbiol. (2004) [Pubmed]
  12. In vitro antiproliferative activity of 4-substituted 2-(2-hydroxyphenyl)thiazolines on murine leukemia cells. Elliott, G.T., Nagle, W.A., Kelly, K.F., McCollough, D., Bona, R.L., Burns, E.R. J. Med. Chem. (1989) [Pubmed]
  13. Crystal and molecular structure of sym-homospermidine monohydrate. Ramaswamy, S., Murthy, M.R. Indian J. Biochem. Biophys. (1991) [Pubmed]
  14. Classification of three airborne bacteria and proposal of Hymenobacter aerophilus sp. nov. Buczolits, S., Denner, E.B., Vybiral, D., Wieser, M., Kämpfer, P., Busse, H.J. Int. J. Syst. Evol. Microbiol. (2002) [Pubmed]
  15. A possible role of cadaverine in the biosynthesis of polyamines in the Japanese newt testis. Matsuzaki, S., Tanaka, S., Suzuki, M., Hamana, K. Endocrinol. Jpn. (1981) [Pubmed]
  16. Further study on polyamines in primitive unicellular eukaryotic algae. Hamana, K., Matsuzaki, S. J. Biochem. (1985) [Pubmed]
  17. Heterologous expression of a bacterial homospermidine synthase gene in transgenic tobacco: effects on the polyamine pathway. Kaiser, A., Sell, S., Hehl, R. Arch. Pharm. (Weinheim) (2002) [Pubmed]
  18. Spermidine metabolism in parasitic protozoa--a comparison to the situation in prokaryotes, viruses, plants and fungi. Kaiser, A.E., Gottwald, A.M., Wiersch, C.S., Maier, W.A., Seitz, H.M. Folia Parasitol. (2003) [Pubmed]
  19. Purification, molecular cloning and expression in Escherichia coli of homospermidine synthase from Rhodopseudomonas viridis. Tholl, D., Ober, D., Martin, W., Kellermann, J., Hartmann, T. Eur. J. Biochem. (1996) [Pubmed]
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