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Chemical Compound Review

Citnatin     trisodium 2-hydroxypropane-1,2,3...

Synonyms: Citreme, Citrosodna, Citrosodina, Citrosodine, Natrocitral, ...
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Disease relevance of citric acid

 

High impact information on citric acid

 

Chemical compound and disease context of citric acid

 

Biological context of citric acid

 

Anatomical context of citric acid

 

Associations of citric acid with other chemical compounds

 

Gene context of citric acid

  • Crystals of human RCC1 suitable for X-ray analysis have been obtained using the seeding technique in hanging drops with sodium citrate as a precipitant [26].
  • VEGF was not different and PF4 was very low or undetectable in Edinburgh plasma and CTAD plasma, while it was significantly higher in sodium citrate plasma [27].
  • BTG and PF4 release from blood anticoagulated with sodium citrate was inhibited by AD6 during a 3 h incubation [28].
  • Crystals of yeast IDH have been obtained and optimized using sodium citrate, a competitive inhibitor of the enzyme, as the precipitating agent [29].
  • A new assay was developed, and the following steady-state kinetic constants were determined for 1-deoxy-D-xylulose 5-phosphate synthase A and B: K(m)(pyruvate) = 0.61 and 3.0 mM, K(m)(D-glyceraldehyde 3-phosphate) = 150 and 120 microM, and V(max) = 1.9 and 1.4 micromol/min/mg in 200 mM sodium citrate (pH 7.4) [30].
 

Analytical, diagnostic and therapeutic context of citric acid

References

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  22. Whole blood storage in citrate and phosphate solutions containing half-strength trisodium citrate: cellular and biochemical studies. Mishler, J.M., Darley, J.H., Cederholm-Williams, S., Wright, G. J. Pathol. (1978) [Pubmed]
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  25. Enantiomeric separation of amino acids using micellar electrokinetic chromatography after pre-column derivatization with the chiral reagent 1-(9-fluorenyl)-ethyl chloroformate. Chan, K.C., Muschik, G.M., Issaq, H.J. Electrophoresis (1995) [Pubmed]
  26. Crystallization and preliminary X-ray analysis of human RCC1, the regulator of chromosome condensation. Renault, L., Nassar, N., Wittinghofer, A., Roth, M., Vetter, I.R. Acta Crystallogr. D Biol. Crystallogr. (1999) [Pubmed]
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  28. Action of AD6 (8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxycarbonylmet hox y coumarin) on human platelets in vitro. Prosdocimi, M., Zatta, A., Gorio, A., Zanetti, A., Dejana, E. Naunyn Schmiedebergs Arch. Pharmacol. (1986) [Pubmed]
  29. Crystallization and preliminary X-ray crystallographic analysis of yeast NAD+-specific isocitrate dehydrogenase. Hu, G., Taylor, A.B., McAlister-Henn, L., Hart, P.J. Acta Crystallograph. Sect. F Struct. Biol. Cryst. Commun. (2005) [Pubmed]
  30. 1-Deoxy-D-xylulose 5-phosphate synthase, the gene product of open reading frame (ORF) 2816 and ORF 2895 in Rhodobacter capsulatus. Hahn, F.M., Eubanks, L.M., Testa, C.A., Blagg, B.S., Baker, J.A., Poulter, C.D. J. Bacteriol. (2001) [Pubmed]
  31. Oral rehydration therapy: efficacy of sodium citrate equals to sodium bicarbonate for correction of acidosis in diarrhoea. Islam, M.R., Samadi, A.R., Ahmed, S.M., Bardhan, P.K., Ali, A. Gut (1984) [Pubmed]
  32. Pre-nucleation crystallization studies on aminoacyl-tRNA synthetases by dynamic light-scattering. Thibault, F., Langowski, J., Leberman, R. J. Mol. Biol. (1992) [Pubmed]
  33. Regional citrate anticoagulation in continuous venovenous hemofiltration in critically ill patients with a high risk of bleeding. Palsson, R., Niles, J.L. Kidney Int. (1999) [Pubmed]
  34. Alterations of platelet aggregation kinetics with ultraviolet laser emission: the "stunned platelet" phenomenon. Topaz, O., Minisi, A.J., Bernardo, N.L., McPherson, R.A., Martin, E., Carr, S.L., Carr, M.E. Thromb. Haemost. (2001) [Pubmed]
 
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