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Chemical Compound Review

Divinylbenzene     1,2-diethenylbenzene

Synonyms: ACMC-1BRAX, AG-G-25729, ANW-41369, AC1Q2AAC, CTK0H5448, ...
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Disease relevance of o-Divinylbenzene


High impact information on o-Divinylbenzene

  • Applying monolithic capillary columns based on poly(styrene/divinylbenzene), the influence of acidic eluents based on trifluoroacetic and heptafluorobutyric acid as well as an alkaline eluent based on triethylamine-acetic acid (pH 9.2) on the separation of synthetic phosphopeptides was evaluated [3].
  • An array of monolithic poly(styrene/divinylbenzene) capillaries with individual column thermostats was constructed to demonstrate its utility for the separation of nucleic acids, proteins, and tryptic digests in combination with UV absorbance detection [4].
  • The use of tetrahydrofuran/decanol as porogens for the fabrication of micropellicular poly(styrene/divinylbenzene) monoliths enabled the rapid and highly efficient separation of peptides and proteins by reversed-phase high-performance liquid chromatography (RP-HPLC) [5].
  • Aliquots (10 microL) are chromatographed isocratically in equivolume mixtures of methanol and water on a column of styrene divinylbenzene and the refractive index of the effluent is measured [6].
  • We studied the role of altered gastric emptying in 50 patients before surgery, 1-4 weeks after surgery, and 2-24 months after surgery using technetium-99m pentetate in water for liquid meals and a Tc-99m styrene divinylbenzene copolymer resin in oatmeal for semisolid meals [7].

Biological context of o-Divinylbenzene


Anatomical context of o-Divinylbenzene


Associations of o-Divinylbenzene with other chemical compounds

  • The PCR samples were separated and quantified using a polystyrene divinylbenzene C 18 column [12].
  • Solid-phase microextraction (SPME), using a polydimethylsiloxane/divinylbenzene (PDMS/DVB) fiber, interfaced with liquid chromatography-fluorescence detection (LC-FD) has been applied to the determination of Ochratoxin A (OTA) in wine samples [13].
  • After addition of deuterated internal standard, the optimised HS-SPME extraction with carbowax/divinylbenzene fibres (30 min at 70 degrees C) was done applying salting out with sodium chloride in the presence of pH 7 buffer solution [14].
  • This immobilization of the packed bed was achieved by in situ polymerization of styrene and divinylbenzene in presence of decanol as a porogen and azobisisobutyronitrile as thermal initiator [15].
  • SDS was stably retained in the cross-linked vesicle and was not removed from the vesicle by exhaustive dialysis or ultrafiltration, due to the electrostatic interaction within the cross-linked polymeric framework produced from VBTAC and DVB [16].

Gene context of o-Divinylbenzene

  • Addition of a high concentration of salt (30%, w/v) in the aqueous medium and use of a carbowax/divinylbenzene (CW/DVB) coating led to optimal extraction efficiencies [17].
  • The separation patterns for recombinant derived interleukin-1 beta (IL-1 beta) on the C4 column eluted with TFA-acetonitrile and the DVB column eluted with acetic acid-acetonitrile were similar, but only the polymeric column was able to separate the components present in an iodinated IL-1 beta preparation [2].
  • Using a standardized sample (0.1 g of a freeze dried soybean extract/25 mL of water); eight SPE cartridges with a wide range of sorbents (C18, divinylbenzene and modified divinylbenzene) from different suppliers were evaluated and compared [18].
  • NIR fluorescent inclusions are comprised of ICG-labeled polystyrene divinylbenzene beads and Pam78-labeled hydroxyapatite crystals [19].
  • The analysis was performed, by means of luminex technology and with a proteomic approach, on native serum samples, and on the same sera after 2 hours of in vitro incubation with a synthetic based styrenic divinylbenzene resin [20].

Analytical, diagnostic and therapeutic context of o-Divinylbenzene


  1. Pulmonary reaction to intravenously injected polymer beads. Schoen, F.J., Kintanar, E.B., Osol, R.G., Lee, E. J. Biomed. Mater. Res. (1986) [Pubmed]
  2. Alternative mobile phases for the reversed-phase high-performance liquid chromatography of peptides and proteins. Welinder, B.S., Sørensen, H.H. J. Chromatogr. (1991) [Pubmed]
  3. Separation and detection of phosphorylated and nonphosphorylated peptides in liquid chromatography-mass spectrometry using monolithic columns and acidic or alkaline mobile phases. Tholey, A., Toll, H., Huber, C.G. Anal. Chem. (2005) [Pubmed]
  4. Capillary array high-performance liquid chromatography of nucleic acids and proteins. Premstaller, A., Oefner, P.J., Oberacher, H., Huber, C.G. Anal. Chem. (2002) [Pubmed]
  5. High-performance liquid chromatography-electrospray ionization mass spectrometry using monolithic capillary columns for proteomic studies. Premstaller, A., Oberacher, H., Walcher, W., Timperio, A.M., Zolla, L., Chervet, J.P., Cavusoglu, N., van Dorsselaer, A., Huber, C.G. Anal. Chem. (2001) [Pubmed]
  6. New liquid-chromatographic method for measuring polyethylene glycol in urine. Delahunty, T., Hollander, D. Clin. Chem. (1986) [Pubmed]
  7. Morbid obesity treated by gastroplasty: radionuclide gastric emptying studies. Arnstein, N.B., Shapiro, B., Ekhauser, F.E., Dmuchowski, C.F., Knol, J.A., Strodel, W.E., Nakajo, M., Swanson, D.P. Radiology. (1985) [Pubmed]
  8. Biotransformation of diethenylbenzenes, V. Identification of urinary metabolites of 1,2-diethenylbenzene in the rat. Linhart, I., Weidenhoffer, Z., Sedmera, P., Polásekj, M., Smejkal, J. Xenobiotica (1996) [Pubmed]
  9. Solvent effects on coupling yields during rapid solid-phase synthesis of CGRP(8-37) employing in situ neutralization. Taylor, C.K., Abel, P.W., Hulce, M., Smith, D.D. J. Pept. Res. (2005) [Pubmed]
  10. Determination of dopamine and methoxycatecholamines in patient urine by liquid chromatography with electrochemical detection and by capillary electrophoresis coupled with spectrophotometry and mass spectrometry. Vuorensola, K., Sirén, H., Karjalainen, U. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. (2003) [Pubmed]
  11. Identification of impurities and the statistical classification of methamphetamine using headspace solid phase microextraction and gas chromatography-mass spectrometry. Kuwayama, K., Tsujikawa, K., Miyaguchi, H., Kanamori, T., Iwata, Y., Inoue, H., Saitoh, S., Kishi, T. Forensic Sci. Int. (2006) [Pubmed]
  12. A clinically applicable assay for tumoral thymidylate synthase combining reverse transcriptase-PCR and high-performance liquid chromatography. Leccia, J.R., Milano, G., Formento, P., Francoual, M., Formento, J.L., Pierrefite, V. Eur. J. Cancer (1998) [Pubmed]
  13. Determination of Ochratoxin A in wine at sub ng/mL levels by solid-phase microextraction coupled to liquid chromatography with fluorescence detection. Aresta, A., Vatinno, R., Palmisano, F., Zambonin, C.G. Journal of chromatography. A. (2006) [Pubmed]
  14. Automated determination of ethyl carbamate in stone-fruit spirits using headspace solid-phase microextraction and gas chromatography-tandem mass spectrometry. Lachenmeier, D.W., Nerlich, U., Kuballa, T. Journal of chromatography. A. (2006) [Pubmed]
  15. Silica particles encapsulated poly(styrene-divinylbenzene) monolithic stationary phases for mu-high performance liquid chromatography. Bakry, R., St??ggl, W.M., Hochleitner, E.O., Stecher, G., Huck, C.W., Bonn, G.K. Journal of chromatography. A. (2006) [Pubmed]
  16. Highly stable polymerizable vesicles in anionic surfactant/ammonium salt mixtures in the presence of cross-linking monomers for convenient preparation of hollow nanospheres. Oyaizu, K., Shiba, Y., Nakamura, Y., Yuasa, M. Langmuir : the ACS journal of surfaces and colloids. (2006) [Pubmed]
  17. Use of solid-phase microextraction/gas chromatography-electron capture detection for the determination of energetic chemicals in marine samples. Monteil-Rivera, F., Beaulieu, C., Hawari, J. Journal of chromatography. A. (2005) [Pubmed]
  18. Solid-phase extraction of soy isoflavones. Rostagno, M.A., Palma, M., Barroso, C.G. Journal of chromatography. A. (2005) [Pubmed]
  19. Tissue-like phantoms for near-infrared fluorescence imaging system assessment and the training of surgeons. De Grand, A.M., Lomnes, S.J., Lee, D.S., Pietrzykowski, M., Ohnishi, S., Morgan, T.G., Gogbashian, A., Laurence, R.G., Frangioni, J.V. Journal of biomedical optics. (2006) [Pubmed]
  20. Effects of the incubation in vitro with sorbents on serum proteomic pattern and cytokine concentration in cancer patients during chemotherapy-preliminary results. Piccolomini, F., Louwratten, M., Sereni, L., Balestreri, E., Donadio, E., Felicioli, A., Felicioli, R., Donadio, C. Biomed. Pharmacother. (2006) [Pubmed]
  21. Multimode separation of polycyclic aromatic compounds by size exclusion chromatography with poly(divinylbenzene). Lafleur, A.L., Wornat, M.J. Anal. Chem. (1988) [Pubmed]
  22. Poly(glycidyl methacrylate-divinylbenzene-triallylisocyanurate) continuous-bed protein chromatography. Zhang, M., Sun, Y. Journal of chromatography. A. (2001) [Pubmed]
  23. Formation of artefacts during air analysis of volatile amines by solid-phase micro extraction. Lestremau, F., Desauziers, V., Fanlo, J.L. The Analyst. (2001) [Pubmed]
  24. Determination of geosmin and 2-methylisoborneol in water using solid-phase microextraction and gas chromatography-chemical ionisation/electron impact ionisation-ion-trap mass spectrometry. McCallum, R., Pendleton, P., Schumann, R., Trinh, M.U. The Analyst. (1998) [Pubmed]
  25. Improved detection of polycyclic aromatic compounds in complex mixtures by liquid chromatographic fractionation on poly(divinylbenzene) prior to gas chromatography-mass spectrometry. Application to the analysis of diesel particulates. Jiao, K., Lafleur, A.L. Journal of chromatography. A. (1997) [Pubmed]
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