Disease relevance of Mecrylate

• Certain strains of Streptococcus sanguis adhere (Adh+) selectively to human platelets and, in plasma, induce them to aggregate (Agg+) into in vitro thrombi [1].
• Twelve consecutive patients with postresectional bronchopleural fistula were treated with endoscopic application of tissue glue adhesive (methyl-2-cyanoacrylate) [2].
• The Krazy Glue-treated ears developed seromas with histologic evidence of acute inflammation, tissue necrosis, and chronic foreign body giant cell reaction [3].
• The authors report four cases of patients in desperate clinical situations where cyanoacrylate adhesive (Krazy Glue) was successfully used to control hemorrhage [4].
• Methyl-2-cyanoacrylate, a widely used material for coating cerebral aneurysm, was recently withdrawn [5].

Psychiatry related information on Mecrylate

• Motivating HIV Positive Women to Adhere to Antiretroviral Therapy and Risk Reduction Behavior: The KHARMA Project [6].

High impact information on Mecrylate

• Retinal Pigment Epithelial Cells Synthesize Laminins, Including Laminin 5, and Adhere to Them through {alpha}3- and {alpha}6-Containing Integrins [7].
• Strains with different platelet interactivity phenotypes were distinguished with a panel of four murine monoclonal antibodies (MAbs) raised against Adh+ Agg+ strain 133-79 and screened to rule out artifactual reactions with antigenic components in culture media [1].
• This study was undertaken to evaluate the efficacy of ethyl-2-cyanoacrylate glue (Krazy Glue, KG) in obtaining prompt hemostasis in vascular anastomoses in a heparinized canine model [8].
• Furthermore, it appears that the mere application of methyl-2-cyanoacrylate to the periosteum overlying a suture will consistently cause the formation of a bony bridge in growing rabbits but not in nongrowing animals [9].
• Premature fusion of the coronal suture was produced in 9-day-old rabbits by immobilization of the suture area bilaterally with methyl-cyanoacrylate adhesive [10].

Chemical compound and disease context of Mecrylate

• The aneurysm produced was covered by no material (Group A), a cellulose cotton sheet and conventional methyl-2-cyanoacrylate (Group B), a newly produced polyglycolic acid felt and fibrin glue (Group C), or a cellulose cotton sheet and fibrin glue (Group D) [5].

Biological context of Mecrylate

• The use of cyanoacrylate adhesive (Krazy Glue) in cardiac surgery [4].

Anatomical context of Mecrylate

• The local histotoxicity of methyl-2-cyanoacrylate, the strong binding capacity, the abundance of scar tissue, and the distraction of the mucosa, as pointed out by several earlier investigators, were confirmed in this work [11].
• Methyl-2-cyanoacrylate was used for nonsuture end-to-end anastomosis of the ascending colon in 35 male Sprague-Dawley rats [11].
• METHODS: A sutureless pericardial patch was glued to the myocardium with commercially available household cyanoacrylate (Krazy Glue) in seven patients [12].
• Since the nonsuture repair of blood vessels with methyl-2-cyanoacrylate was described in 1960, the advantages of a tissue adhesive over conventional sutures became evident [13].

Associations of Mecrylate with other chemical compounds

• To objectively determine how these adhesives affect cartilage viability, freshly harvested cartilage from septoplasty procedures was bonded in vitro with one of four cyanoacrylate adhesives: Histoacryl, Bucrylate, Krazy Glue, or Eastman 910 monomer [14].

Gene context of Mecrylate

• Cyanoacrylate-containing adhesives such as Super Glue, Krazy Glue, and a vast array of artificial nail adhesives are monomers which rapidly polymerize and bond in the presence of water or weak bases [15].

Analytical, diagnostic and therapeutic context of Mecrylate

• The MAbs reacted selectively with Adh+ Agg+ strains in a direct-binding, whole-cell, enzyme-linked immunosorbent assay and also inhibited their interactions with platelets [1].
• A repair compound made by mixing pink denture base acrylic resin polymer and methyl-2-cyanoacrylate makes it possible to accomplish many denture corrections permanently as in-office procedures [16].

References