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Chemical Compound Review

Cyanoacrylate     methyl 2-cyanoprop-2-enoate

Synonyms: Cyanolit, Mecrilat, Mecrilate, Mecrilato, Mecrylate, ...
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Disease relevance of Mecrylate


Psychiatry related information on Mecrylate


High impact information on Mecrylate

  • Retinal Pigment Epithelial Cells Synthesize Laminins, Including Laminin 5, and Adhere to Them through {alpha}3- and {alpha}6-Containing Integrins [7].
  • Strains with different platelet interactivity phenotypes were distinguished with a panel of four murine monoclonal antibodies (MAbs) raised against Adh+ Agg+ strain 133-79 and screened to rule out artifactual reactions with antigenic components in culture media [1].
  • This study was undertaken to evaluate the efficacy of ethyl-2-cyanoacrylate glue (Krazy Glue, KG) in obtaining prompt hemostasis in vascular anastomoses in a heparinized canine model [8].
  • Furthermore, it appears that the mere application of methyl-2-cyanoacrylate to the periosteum overlying a suture will consistently cause the formation of a bony bridge in growing rabbits but not in nongrowing animals [9].
  • Premature fusion of the coronal suture was produced in 9-day-old rabbits by immobilization of the suture area bilaterally with methyl-cyanoacrylate adhesive [10].

Chemical compound and disease context of Mecrylate

  • The aneurysm produced was covered by no material (Group A), a cellulose cotton sheet and conventional methyl-2-cyanoacrylate (Group B), a newly produced polyglycolic acid felt and fibrin glue (Group C), or a cellulose cotton sheet and fibrin glue (Group D) [5].

Biological context of Mecrylate


Anatomical context of Mecrylate


Associations of Mecrylate with other chemical compounds

  • To objectively determine how these adhesives affect cartilage viability, freshly harvested cartilage from septoplasty procedures was bonded in vitro with one of four cyanoacrylate adhesives: Histoacryl, Bucrylate, Krazy Glue, or Eastman 910 monomer [14].

Gene context of Mecrylate

  • Cyanoacrylate-containing adhesives such as Super Glue, Krazy Glue, and a vast array of artificial nail adhesives are monomers which rapidly polymerize and bond in the presence of water or weak bases [15].

Analytical, diagnostic and therapeutic context of Mecrylate


  1. Phenotypic characterization of Streptococcus sanguis virulence factors associated with bacterial endocarditis. Herzberg, M.C., Gong, K., MacFarlane, G.D., Erickson, P.R., Soberay, A.H., Krebsbach, P.H., Manjula, G., Schilling, K., Bowen, W.H. Infect. Immun. (1990) [Pubmed]
  2. Postoperative bronchopleural fistula: endoscopic closure in 12 patients. Scappaticci, E., Ardissone, F., Ruffini, E., Baldi, S., Mancuso, M. Ann. Thorac. Surg. (1994) [Pubmed]
  3. Histotoxicity of cyanoacrylate tissue adhesives. A comparative study. Toriumi, D.M., Raslan, W.F., Friedman, M., Tardy, M.E. Arch. Otolaryngol. Head Neck Surg. (1990) [Pubmed]
  4. The use of cyanoacrylate adhesive (Krazy Glue) in cardiac surgery. Robicsek, F., Rielly, J.P., Marroum, M.C. Journal of cardiac surgery. (1994) [Pubmed]
  5. A novel coating biomaterial for intracranial aneurysms: effects and safety in extra- and intracranial carotid artery. Yasuda, H., Kuroda, S., Nanba, R., Ishikawa, T., Shinya, N., Terasaka, S., Iwasaki, Y., Nagashima, K. Neuropathology : official journal of the Japanese Society of Neuropathology. (2005) [Pubmed]
  6. Motivating HIV Positive Women to Adhere to Antiretroviral Therapy and Risk Reduction Behavior: The KHARMA Project. Holstad, M.M., Diiorio, C., Magowe, M.K. Online journal of issues in nursing [electronic resource]. (2006) [Pubmed]
  7. Retinal Pigment Epithelial Cells Synthesize Laminins, Including Laminin 5, and Adhere to Them through {alpha}3- and {alpha}6-Containing Integrins. Aisenbrey, S., Zhang, M., Bacher, D., Yee, J., Brunken, W.J., Hunter, D.D. Invest. Ophthalmol. Vis. Sci. (2006) [Pubmed]
  8. Control of needle hole bleeding with ethyl-cyanoacrylate glue (Krazy Glue). Citrin, P., Doscher, W., Wise, L., Margolis, I.B. J. Vasc. Surg. (1985) [Pubmed]
  9. Experimental craniosynostosis in growing rabbits. The role of the periosteum. Nappen, D.L., Kokich, V.G. J. Neurosurg. (1983) [Pubmed]
  10. Craniofacial growth following experimental craniosynostosis and craniectomy in rabbits. Persson, K.M., Roy, W.A., Persing, J.A., Rodeheaver, G.T., Winn, H.R. J. Neurosurg. (1979) [Pubmed]
  11. Nonsuture colonic anastomosis. Gennaro, A.R., Moreira, C.A. Dis. Colon Rectum (1976) [Pubmed]
  12. Application of cyanoacrylate adhesive (Krazy Glue) in critical cardiac injuries. Eastman, D.P., Robicsek, F. J. Heart Valve Dis. (1998) [Pubmed]
  13. Use of butyl-2-cyanoacrylate in rabbit auricular cartilage. Fung, R.Q., Ronis, M.L., Mohr, R.M. Archives of otolaryngology (Chicago, Ill. : 1960) (1985) [Pubmed]
  14. Effects of cyanoacrylate tissue adhesives on cartilage graft viability. Quatela, V.C., Futran, N.D., Frisina, R.D. Laryngoscope (1993) [Pubmed]
  15. Cyanoacrylates and corneal abrasion. Dean, B.S., Krenzelok, E.P. J. Toxicol. Clin. Toxicol. (1989) [Pubmed]
  16. In-office permanent denture base correction technique. Ruffino, A.R. The Journal of prosthetic dentistry. (1985) [Pubmed]
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