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MeSH Review

Intracranial Aneurysm

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Disease relevance of Intracranial Aneurysm


Psychiatry related information on Intracranial Aneurysm


High impact information on Intracranial Aneurysm


Chemical compound and disease context of Intracranial Aneurysm

  • The factors that predispose to rupture of berry aneurysms are interrelated in the sense that several of them are known to cause a decrease in the synthesis of prostaglandin E, whereas one of the factors that appears to be protective has the opposite effect [1].
  • We conclude that nimodipine does not increase CBF or alter BP following SAH, but an improved clinical outcome is evident at three months for patients with SAH due to cerebral aneurysm who had been treated with nimodipine [12].
  • In this cooperative study among 13 institutions, 502 patients were treated with antifibrinolytic medication (epsilon-aminocaproic acid or tranexamic acid) within a 14-day period following rupture of an intracranial aneurysm [13].
  • The presence of an underlying cerebral aneurysm was more common among patients with cocaine HCl-associated strokes than alkaloidal cocaine-associated strokes [3].
  • CONCLUSIONS: An atherosclerotic profile including increased total cholesterol concentration and a long smoking history may contribute to the rupture of cerebral aneurysms [14].

Biological context of Intracranial Aneurysm


Anatomical context of Intracranial Aneurysm


Gene context of Intracranial Aneurysm


Analytical, diagnostic and therapeutic context of Intracranial Aneurysm


  1. Risk factors for the development and rupture of intracranial berry aneurysms. de la Monte, S.M., Moore, G.W., Monk, M.A., Hutchins, G.M. Am. J. Med. (1985) [Pubmed]
  2. Immunohistochemical alterations of fibronectin during the formation and proliferative repair of experimental cerebral aneurysms in rats. Futami, K., Yamashita, J., Tachibana, O., Higashi, S., Ikeda, K., Yamashima, T. Stroke (1995) [Pubmed]
  3. A comparative study of the cerebrovascular complications of cocaine: alkaloidal versus hydrochloride--a review. Levine, S.R., Brust, J.C., Futrell, N., Brass, L.M., Blake, D., Fayad, P., Schultz, L.R., Millikan, C.H., Ho, K.L., Welch, K.M. Neurology (1991) [Pubmed]
  4. Treatment of refractory complex-partial status epilepticus with propofol: case report. Begemann, M., Rowan, A.J., Tuhrim, S. Epilepsia (2000) [Pubmed]
  5. Cardiac performance preserved despite thiopental loading. Stone, J.G., Young, W.L., Marans, Z.S., Khambatta, H.J., Solomon, R.A., Smith, C.R., Ostapkovich, N., Jamdar, S.C., Diaz, J. Anesthesiology (1993) [Pubmed]
  6. Electroconvulsive therapy and intracranial aneurysm. Prevention of blood pressure elevation in a normotensive patient by hydralazine and propranolol. Husum, B., Vester-Andersen, T., Buchmann, G., Bolwig, T.G. Anaesthesia. (1983) [Pubmed]
  7. Intracranial aneurysms in autosomal dominant polycystic kidney disease. Chapman, A.B., Rubinstein, D., Hughes, R., Stears, J.C., Earnest, M.P., Johnson, A.M., Gabow, P.A., Kaehny, W.D. N. Engl. J. Med. (1992) [Pubmed]
  8. Severe alpha 1-antitrypsin deficiency and intracranial aneurysms. Elzouki, A.N., Eriksson, S. Lancet (1994) [Pubmed]
  9. Some patients with cerebral aneurysms are deficient in type III collagen. Pope, F.M., Nicholls, A.C., Narcisi, P., Bartlett, J., Neil-Dwyer, G., Doshi, B. Lancet (1981) [Pubmed]
  10. A haplotype spanning two genes, ELN and LIMK1, decreases their transcripts and confers susceptibility to intracranial aneurysms. Akagawa, H., Tajima, A., Sakamoto, Y., Krischek, B., Yoneyama, T., Kasuya, H., Onda, H., Hori, T., Kubota, M., Machida, T., Saeki, N., Hata, A., Hashiguchi, K., Kimura, E., Kim, C.J., Yang, T.K., Lee, J.Y., Kimm, K., Inoue, I. Hum. Mol. Genet. (2006) [Pubmed]
  11. Vascular expression of polycystin-2. Torres, V.E., Cai, Y., Chen, X., Wu, G.Q., Geng, L., Cleghorn, K.A., Johnson, C.M., Somlo, S. J. Am. Soc. Nephrol. (2001) [Pubmed]
  12. Early intervention with nimodipine in subarachnoid haemorrhage. Neil-Dwyer, G., Mee, E., Dorrance, D., Lowe, D. Eur. Heart J. (1987) [Pubmed]
  13. Intracranial aneurysms and subarachnoid hemorrhage. A cooperative study. Antifibrinolytic therapy in recent onset subarachnoid hemorrhage. Nibbelink, D.W., Torner, J.C., Henderson, W.G. Stroke (1975) [Pubmed]
  14. Are cerebral aneurysms atherosclerotic? Adamson, J., Humphries, S.E., Ostergaard, J.R., Voldby, B., Richards, P., Powell, J.T. Stroke (1994) [Pubmed]
  15. Use of antihypertension agents for the suppression of arterial pulse pressure waveforms in patients with intracranial aneurysms. Turner, C.L., Wilkinson, I.B., Kirkpatrick, P.J. J. Neurosurg. (2006) [Pubmed]
  16. Vasospasm and regional cerebral blood flow (rCBF) in patients with ruptured intracranial aneurysm: serial rCBF studies with the xenon-133 inhalation method. Yamakami, I., Isobe, K., Yamaura, A., Nakamura, T., Makino, H. Neurosurgery (1983) [Pubmed]
  17. Matrix metalloproteinase-9 coding sequence single-nucleotide polymorphisms in caucasians with intracranial aneurysms. Krex, D., Kotteck, K., König, I.R., Ziegler, A., Schackert, H.K., Schackert, G. Neurosurgery (2004) [Pubmed]
  18. Furosemide in the intraoperative reduction of intracranial pressure in the patient with subarachnoid hemorrhage. Samson, D., Beyer, C.W. Neurosurgery (1982) [Pubmed]
  19. Effects of blood coagulation factor XIII on the development of experimental cerebral aneurysms in rats. Kang, Y., Hashimoto, N., Kikuchi, H., Yamazoe, N., Hazama, F. J. Neurosurg. (1990) [Pubmed]
  20. Autoregulatory vasodilation of parenchymal vessels is impaired during cerebral vasospasm. Yundt, K.D., Grubb, R.L., Diringer, M.N., Powers, W.J. J. Cereb. Blood Flow Metab. (1998) [Pubmed]
  21. Basic fibroblast growth factor may repair experimental cerebral aneurysms in rats. Futami, K., Yamashita, J., Tachibana, O., Kida, S., Higashi, S., Ikeda, K., Yamashima, T. Stroke (1995) [Pubmed]
  22. Endovascular treatment of giant aneurysms which cause visual loss. Vargas, M.E., Kupersmith, M.J., Setton, A., Nelson, K., Berenstein, A. Ophthalmology (1994) [Pubmed]
  23. Long-term outcome of renal transplantation in autosomal dominant polycystic kidney disease. Fitzpatrick, P.M., Torres, V.E., Charboneau, J.W., Offord, K.P., Holley, K.E., Zincke, H. Am. J. Kidney Dis. (1990) [Pubmed]
  24. Treatment of multiple visceral aneurysms in a 20-year-old patient. Woo, E.Y., Fairman, R.M. J. Vasc. Surg. (2004) [Pubmed]
  25. Genetic analysis of MMP3, MMP9, and PAI-1 in Finnish patients with abdominal aortic or intracranial aneurysms. Yoon, S., Tromp, G., Vongpunsawad, S., Ronkainen, A., Juvonen, T., Kuivaniemi, H. Biochem. Biophys. Res. Commun. (1999) [Pubmed]
  26. Association of positional and functional candidate genes FGF1, FBN2, and LOX on 5q31 with intracranial aneurysm. Yoneyama, T., Kasuya, H., Onda, H., Akagawa, H., Jinnai, N., Nakajima, T., Hori, T., Inoue, I. J. Hum. Genet. (2003) [Pubmed]
  27. Collagen type I alpha2 (COL1A2) is the susceptible gene for intracranial aneurysms. Yoneyama, T., Kasuya, H., Onda, H., Akagawa, H., Hashiguchi, K., Nakajima, T., Hori, T., Inoue, I. Stroke (2004) [Pubmed]
  28. Management of polycystic liver disease. Everson, G.T., Taylor, M.R. Current gastroenterology reports. (2005) [Pubmed]
  29. Prevention of rat cerebral aneurysm formation by inhibition of nitric oxide synthase. Fukuda, S., Hashimoto, N., Naritomi, H., Nagata, I., Nozaki, K., Kondo, S., Kurino, M., Kikuchi, H. Circulation (2000) [Pubmed]
  30. Alpha 1-antitrypsin deficiency in intracranial aneurysms and cervical artery dissection. Schievink, W.I., Prakash, U.B., Piepgras, D.G., Mokri, B. Lancet (1994) [Pubmed]
  31. Elastic skeleton of intracranial cerebral aneurysms in rats. Yamazoe, N., Hashimoto, N., Kikuchi, H., Hazama, F. Stroke (1990) [Pubmed]
  32. Follow-up of intracranial aneurysms treated with detachable coils: comparison of gadolinium-enhanced 3D time-of-flight MR angiography and digital subtraction angiography. Boulin, A., Pierot, L. Radiology. (2001) [Pubmed]
  33. Controlled hypotension with adenosine in cerebral aneurysm surgery. Sollevi, A., Lagerkranser, M., Irestedt, L., Gordon, E., Lindquist, C. Anesthesiology (1984) [Pubmed]
  34. The dopamine withdrawal test following surgery for intracranial aneurysms. Mendelow, A.D., Dharker, S., Patterson, J., Nath, F., Teasdale, G.M. J. Neurol. Neurosurg. Psychiatr. (1986) [Pubmed]
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