Disease relevance of Cyacrin

• Ruptured de novo aneurysm induced by ethyl 2-cyanoacrylate: case report [1].
• Ectopic contact dermatitis from ethyl cyanoacrylate instant adhesives [2].
• Occupational allergic contact dermatitis from ethyl cyanoacrylate [3].
• On each of days 1, 7, 15, 30, 45 and 60, six rats from the study group and six rats from the control group were sacrificed and analyzed for each relevant organ in terms of bonding of ethyl 2-cyanoacrylate polymers to tissue, foreign body reaction, inflammatory reactions, and necrosis [4].
• Shortly thereafter she underwent microvascular decompression for left-side facial palsy; again ethyl 2-cyanoacrylate was used [5].

High impact information on Cyacrin

• Both metallocenes function as photoinitiators for the anionic polymerization of ethyl 2-cyanoacrylate, and the kinetics and mechanism of this process have been investigated [6].
• The right anteroinferior cerebellar artery, which was compressing the exit zone of the facial nerve, was detached and fixed to the dura mater with ethyl 2-cyanoacrylate [1].
• Poly(ethoxy-ethyl 2-cyanoacrylate) and poly(methyl 2-cyanoacrylate) microspheres inhibited cell growth in a smaller amount than poly-(isobutyl 2-cyanoacrylate) and poly (ethyl 2-cyanoacrylate) microspheres [7].
• Neuropathological changes related to the transorbital application of ethyl 2-cyanoacrylate adhesive to the basal cerebral arteries of cats [8].
• Clinical experience would suggest that ethyl 2-cyanoacrylate can be used in difficult situations as long as care is taken to protect the brain and local blood vessels [8].

Biological context of Cyacrin

• OBJECTIVES: To investigate experimentally the possible histopathological effects of ethyl 2-cyanoacrylate glue when used as a tissue adhesive in cardiovascular and thoracic surgery [4].
• The association between pulmonary obstruction (e.g., asthma) and occupational exposure to methyl cyanoacrylate (MCA) and ethyl cyanoacrylate (ECA) was examined in an occupational cohort of 450 persons at an adhesive production facility in Puerto Rico [9].

Anatomical context of Cyacrin

• One bulge was stuck to the dura mater of the pyramis by ethyl 2-cyanoacrylate, which had been used in the microvascular decompression 9 years previously [1].
• Similar successful use of ethyl cyanoacrylate in patients would provide a safe method of taking a specimen from a mass for biopsy in the pancreas [10].
• For histopathological investigation, a study group of 144 rats in which intentionally produced lesions in myocardium (n=36), ascending aorta (n=36), lung (n=36) and abdominal aorta (n=36) were closed by using ethyl 2-cyanoacrylate was compared with the control group (n=144) in which the same lesions were closed by using sutures [4].
• We used a Teflon patch fixed to the ventricular wall with a biocompatible synthetic glue, an ethyl-2-cyanoacrylate monomer, without any direct suturing of the infarcted myocardium [11].
• Effect of ethyl 2-cyanoacrylate adhesive on rabbit vaginal mucous membrane [12].

Associations of Cyacrin with other chemical compounds

• Literature on nitromethane, ethyl cyanoacrylate, and other exposures in the workplace was reviewed [13].
• The patch test results obtained in these patients demonstrated that 2-hydroxyethyl methacrylate and ethyl cyanoacrylate were the only 2 allergens needed to diagnose contact allergy to acrylic-containing nail cosmetics, except for 1 patient who reacted only to her nail preparation used and in which we were unable to identify the allergen [14].
• Magnetic poly(ethyl-2-cyanoacrylate) (PECA) nanoparticles containing anti-cancer drugs (Cisplatin and Gemcitabine) were prepared by inter-facial polymerization [15].

Analytical, diagnostic and therapeutic context of Cyacrin

• In vitro and in vivo studies for modified ethyl cyanoacrylate regimens for sclerotherapy [16].
• Patch test reactions were strongly positive to ethyl cyanoacrylate adhesives [2].
• Ethyl-2-cyanoacrylate fixation of the cranial bone flap after craniotomy [17].
• Clinico-pathological observations on alpha-cyanoacrylate in endodontics. 1. Coating effects of exposed human vital pulp with ethyl cyanoacrylate [18].
• Ethyl 2-cyanoacrylate was applied subcutaneously to four rats; its presence in blood and urine was investigated by using High Pressure Liquid Chromatography [19].

References