Chemical Compound Review:
O-Tyrosine 2-amino-3-(2- hydroxyphenyl)propanoic acid
Synonyms:
Ortho-tyrosine, DL-o-Tyrosine, o-DL-Tyrosine, H-DL-O-TYR-OH, D,L-o-Tyrosine, ...
- Reactive carbonyls and polyunsaturated fatty acids produce a hydroxyl radical-like species: a potential pathway for oxidative damage of retinal proteins in diabetes. Pennathur, S., Ido, Y., Heller, J.I., Byun, J., Danda, R., Pergola, P., Williamson, J.R., Heinecke, J.W. J. Biol. Chem. (2005)
- Urinary ortho-tyrosine excretion in diabetes mellitus and renal failure: evidence for hydroxyl radical production. Molnár, G.A., Wagner, Z., Markó, L., Kó Szegi, T., Mohás, M., Kocsis, B., Matus, Z., Wagner, L., Tamaskó, M., Mazák, I., Laczy, B., Nagy, J., Wittmann, I. Kidney Int. (2005)
- Increased oxidative stress in kwashiorkor. Manary, M.J., Leeuwenburgh, C., Heinecke, J.W. J. Pediatr. (2000)
- Hydroxyl radical production during myocardial ischemia and reperfusion in cats. O'Neill, C.A., Fu, L.W., Halliwell, B., Longhurst, J.C. Am. J. Physiol. (1996)
- Iron overload diminishes atherosclerosis in apoE-deficient mice. Kirk, E.A., Heinecke, J.W., LeBoeuf, R.C. J. Clin. Invest. (2001)
- Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o'-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease. Pennathur, S., Jackson-Lewis, V., Przedborski, S., Heinecke, J.W. J. Biol. Chem. (1999)
- Hydroxyl radical generation during exercise increases mitochondrial protein oxidation and levels of urinary dityrosine. Leeuwenburgh, C., Hansen, P.A., Holloszy, J.O., Heinecke, J.W. Free Radic. Biol. Med. (1999)
- Aromatic hydroxylation in nasal lavage fluid following ambient ozone exposure. Frischer, T., Pullwitt, A., Kühr, J., Meinert, R., Haschke, N., Studnicka, M., Lubec, G. Free Radic. Biol. Med. (1997)
- 6-hydroxydopamine increases the hydroxylation and nitration of phenylalanine in vivo: implication of peroxynitrite formation. Ferger, B., Themann, C., Rose, S., Halliwell, B., Jenner, P. J. Neurochem. (2001)
- Design and synthesis of enantiomers of 3,5-dinitro-o-tyrosine: alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropanoic acid (AMPA) receptor antagonists. Sun, G., Slavica, M., Uretsky, N.J., Wallace, L.J., Shams, G., Weinstein, D.M., Miller, J.C., Miller, D.D. J. Med. Chem. (1998)
- Intensity and anisotropy decays of the tyrosine calmodulin proteolytic fragments, as studied by GHz frequency-domain fluorescence. Gryczynski, I., Steiner, R.F., Lakowicz, J.R. Biophys. Chem. (1991)
- Detection of o-tyrosine in irradiated chicken by reverse-phase HPLC and fluorescence detection. Ibe, F.I., Grinter, R., Massey, R., Homer, R. Food additives and contaminants. (1991)
- Caloric restriction attenuates dityrosine cross-linking of cardiac and skeletal muscle proteins in aging mice. Leeuwenburgh, C., Wagner, P., Holloszy, J.O., Sohal, R.S., Heinecke, J.W. Arch. Biochem. Biophys. (1997)
- Ingredients contribute to variation in production of reactive oxygen species by areca quid. Chen, P.H., Tsai, C.C., Lin, Y.C., Ko, Y.C., Yang, Y.H., Shieh, T.Y., Ho, P.S., Li, C.M., Min-Shan Ko, A., Chen, C.H. J. Toxicol. Environ. Health Part A (2006)
- Affinity of 1,2-substituted oxytocin analogues to the uterus receptor: Free-Wilson and Hansch analysis. Pliska, V. Experientia (1978)
- Hyperoxic injury of immature guinea pig lung is mediated via hydroxyl radicals. Kelly, F.J., Lubec, G. Pediatr. Res. (1995)
- Comparative time-courses of copper-ion-mediated protein and lipid oxidation in low-density lipoprotein. Knott, H.M., Baoutina, A., Davies, M.J., Dean, R.T. Arch. Biochem. Biophys. (2002)
- Evidence against the involvement of reactive oxygen species in the pathogenesis of neuronal death in Down's syndrome and Alzheimer's disease. Hayn, M., Kremser, K., Singewald, N., Cairns, N., Nemethova, M., Lubec, B., Lubec, G. Life Sci. (1996)
- The hydroxyl radical formation system in polymorphonuclear leukocytes. Kawakami, N., Hayakawa, T., Shimohama, S., Fujimoto, S. Biol. Pharm. Bull. (1999)
- Effect of intravenous iron supplementation on erythropoiesis in erythropoietin-treated premature infants. Pollak, A., Hayde, M., Hayn, M., Herkner, K., Lombard, K.A., Lubec, G., Weninger, M., Widness, J.A. Pediatrics (2001)
- Decrease of brain protein kinase C, protein kinase A, and cyclin-dependent kinase correlating with pH precedes neuronal death in neonatal asphyxia. Lubec, B., Dell'Anna, E., Fang-Kircher, S., Marx, M., Herrera-Marschitz, M., Lubec, G. J. Investig. Med. (1997)
- Oxyradical damage and mitochondrial enzyme activities in the mdx mouse. Hauser, E., Höger, H., Bittner, R., Widhalm, K., Herkner, K., Lubec, G. Neuropediatrics. (1995)
- Quantification of o,o'-dityrosine, o-nitrotyrosine, and o-tyrosine in cat urine samples by LC/ electrospray ionization-MS/MS using isotope dilution. Marvin, L.F., Delatour, T., Tavazzi, I., Fay, L.B., Cupp, C., Guy, P.A. Anal. Chem. (2003)
- Determination of m-tyrosine and o-tyrosine in human serum by high-performance liquid chromatography with fluorimetric detection. Ishimitsu, S., Fujimoto, S., Ohara, A. J. Chromatogr. (1986)