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Chemical Compound Review

BNPS-skatol     3-bromo-3-methyl-2-(2- nitrophenyl)sulfanyl...

Synonyms: Bnps-skatole, BIM105, SureCN168417, B4651_SIGMA, NSC-240875, ...
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Disease relevance of NSC 240875


High impact information on NSC 240875

  • The amino acid sequence of the light chain of bovine protein C was determined by sequenator analysis of the carboxymethylated light chain and fragments obtained by cyanogen bromide treatment, tryptic digestion after blocking of lysine residues, and cleavage with 2-(2-nitrophenylsulfenyl)-3-methyl-3-bromoindolenine (BNPS-skatole) [5].
  • The complete amino acid sequence of bovine bone matrix Gla protein (MGP) was determined by automatic sequence analysis of the intact protein and of peptides isolated from tryptic and BNPS-skatole digests [6].
  • Examination of the catalytic core of PAL (PALcc) using trypsin, BNPS skatole, and COOH-terminally truncated proteins failed to identify stable subdomains [7].
  • BNPS-skatole cleavages of [3H]-25-OH-D3-3-BE- and 3H-1alpha,25(OH)2D3-3-BE-labeled DBP samples produced the same labeled peptide (N-terminal), demonstrating the specificity of labeling by these analogs [8].
  • The C-terminal half of the bovine myelin basic protein, peptide 89-169, was treated with BNPS-skatole [2-(2-nitrophenylsulfenyl)-3-methyl-3'-bromoindolenine], and the products were isolated by repeated gel filtration through Sephadex G-50 [9].

Biological context of NSC 240875

  • Chemical degradation experiments were undertaken in an effort to produce identifiable fragments to which these signals could be assigned, including full and partial acid hydrolysis and tryptophan-targeted BNPS-skatole treatment [10].

Anatomical context of NSC 240875


Associations of NSC 240875 with other chemical compounds


Gene context of NSC 240875


Analytical, diagnostic and therapeutic context of NSC 240875


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