Gene Review:
Abcc2 - ATP-binding cassette, sub-family C...
Mus musculus
Synonyms:
AI173996, ATP-binding cassette sub-family C member 2, Abc30, Canalicular multispecific organic anion transporter 1, Cmoat, ...
- Carcinogen and anticancer drug transport by Mrp2 in vivo: studies using Mrp2 (Abcc2) knockout mice. Vlaming, M.L., Mohrmann, K., Wagenaar, E., de Waart, D.R., Elferink, R.P., Lagas, J.S., van Tellingen, O., Vainchtein, L.D., Rosing, H., Beijnen, J.H., Schellens, J.H., Schinkel, A.H. J. Pharmacol. Exp. Ther. (2006)
- Effect of Adenovirus-Mediated RNA Interference on Endogenous MicroRNAs in a Mouse Model of Multidrug Resistance Protein 2 Gene Silencing. Narvaiza, I., Aparicio, O., Vera, M., Razquin, N., Bortolanza, S., Prieto, J., Fortes, P. J. Virol. (2006)
- Polymorphisms of MRP1 (ABCC1) and related ATP-dependent drug transporters. Conseil, G., Deeley, R.G., Cole, S.P. Pharmacogenet. Genomics (2005)
- Charged amino acids in the transmembrane domains are involved in the determination of the substrate specificity of rat Mrp2. Ito, K., Suzuki, H., Sugiyama, Y. Mol. Pharmacol. (2001)
- Protective role of hydroxysteroid sulfotransferase in lithocholic acid-induced liver toxicity. Kitada, H., Miyata, M., Nakamura, T., Tozawa, A., Honma, W., Shimada, M., Nagata, K., Sinal, C.J., Guo, G.L., Gonzalez, F.J., Yamazoe, Y. J. Biol. Chem. (2003)
- Functional analysis of a canalicular multispecific organic anion transporter cloned from rat liver. Ito, K., Suzuki, H., Hirohashi, T., Kume, K., Shimizu, T., Sugiyama, Y. J. Biol. Chem. (1998)
- The important role of bcrp (abcg2) in the biliary excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in mice. Zamek-Gliszczynski, M.J., Nezasa, K., Tian, X., Kalvass, J.C., Patel, N.J., Raub, T.J., Brouwer, K.L. Mol. Pharmacol. (2006)
- Multidrug resistance protein 2 is an important determinant of Paclitaxel pharmacokinetics. Lagas, J.S., Vlaming, M.L., van Tellingen, O., Wagenaar, E., Jansen, R.S., Rosing, H., Beijnen, J.H., Schinkel, A.H. Clin. Cancer Res. (2006)
- Characterization of Hepatobiliary Transport Systems of a Novel alpha4beta1/alpha4beta7 Dual Antagonist, TR-14035. Tsuda-Tsukimoto, M., Maeda, T., Iwanaga, T., Kume, T., Tamai, I. Pharm. Res. (2006)
- Functional analysis of mouse and monkey multidrug resistance-associated protein 2 (mrp2). Ninomiya, M., Ito, K., Hiramatsu, R., Horie, T. Drug Metab. Dispos. (2006)
- P-glycoprotein plays a major role in the efflux of fexofenadine in the small intestine and blood-brain barrier, but only a limited role in its biliary excretion. Tahara, H., Kusuhara, H., Fuse, E., Sugiyama, Y. Drug Metab. Dispos. (2005)
- Altered hepatobiliary disposition of 5 (and 6)-carboxy-2',7'-dichlorofluorescein in Abcg2 (Bcrp1) and Abcc2 (Mrp2) knockout mice. Nezasa, K., Tian, X., Zamek-Gliszczynski, M.J., Patel, N.J., Raub, T.J., Brouwer, K.L. Drug Metab. Dispos. (2006)
- Physiological and pharmacological functions of Mrp2, Mrp3 and Mrp4 as determined from recent studies on gene-disrupted mice. Kruh, G.D., Belinsky, M.G., Gallo, J.M., Lee, K. Cancer Metastasis Rev. (2007)