Gene Review:
Abcg2 - ATP-binding cassette, sub-family G (WHITE)...
Mus musculus
Synonyms:
ABC15, ABCP, AI428558, ATP-binding cassette sub-family G member 2, Abcp, ...
- Tissue distribution and hormonal regulation of the breast cancer resistance protein (Bcrp/Abcg2) in rats and mice. Tanaka, Y., Slitt, A.L., Leazer, T.M., Maher, J.M., Klaassen, C.D. Biochem. Biophys. Res. Commun. (2005)
- Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo. Zhou, S., Morris, J.J., Barnes, Y., Lan, L., Schuetz, J.D., Sorrentino, B.P. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Breast cancer resistance protein (Bcrp/abcg2) is a major determinant of sulfasalazine absorption and elimination in the mouse. Zaher, H., Khan, A.A., Palandra, J., Brayman, T.G., Yu, L., Ware, J.A. Mol. Pharm. (2006)
- Persistent expression of the ATP-binding cassette transporter, Abcg2, identifies cardiac SP cells in the developing and adult heart. Martin, C.M., Meeson, A.P., Robertson, S.M., Hawke, T.J., Richardson, J.A., Bates, S., Goetsch, S.C., Gallardo, T.D., Garry, D.J. Dev. Biol. (2004)
- Cellular and molecular regulation of skeletal muscle side population cells. Meeson, A.P., Hawke, T.J., Graham, S., Jiang, N., Elterman, J., Hutcheson, K., Dimaio, J.M., Gallardo, T.D., Garry, D.J. Stem Cells (2004)
- Akt signaling regulates side population cell phenotype via Bcrp1 translocation. Mogi, M., Yang, J., Lambert, J.F., Colvin, G.A., Shiojima, I., Skurk, C., Summer, R., Fine, A., Quesenberry, P.J., Walsh, K. J. Biol. Chem. (2003)
- Contribution of the ABC transporters Bcrp1 and Mdr1a/1b to the side population phenotype in mammary gland and bone marrow of mice. Jonker, J.W., Freeman, J., Bolscher, E., Musters, S., Alvi, A.J., Titley, I., Schinkel, A.H., Dale, T.C. Stem Cells (2005)
- A mutation hot spot in the Bcrp1 (Abcg2) multidrug transporter in mouse cell lines selected for Doxorubicin resistance. Allen, J.D., Jackson, S.C., Schinkel, A.H. Cancer Res. (2002)
- Prospective isolation of murine hematopoietic stem cells by expression of an Abcg2/GFP allele. Tadjali, M., Zhou, S., Rehg, J., Sorrentino, B.P. Stem Cells (2006)
- Hematopoietic cells from mice that are deficient in both Bcrp1/Abcg2 and Mdr1a/1b develop normally but are sensitized to mitoxantrone. Zhou, S., Zong, Y., Lu, T., Sorrentino, B.P. BioTechniques (2003)
- The important role of bcrp (abcg2) in the biliary excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in mice. Zamek-Gliszczynski, M.J., Nezasa, K., Tian, X., Kalvass, J.C., Patel, N.J., Raub, T.J., Brouwer, K.L. Mol. Pharmacol. (2006)
- Substrate overlap between Mrp4 and Abcg2/Bcrp affects purine analogue drug cytotoxicity and tissue distribution. Takenaka, K., Morgan, J.A., Scheffer, G.L., Adachi, M., Stewart, C.F., Sun, D., Leggas, M., Ejendal, K.F., Hrycyna, C.A., Schuetz, J.D. Cancer Res. (2007)
- Increased expression of the Abcg2 transporter during erythroid maturation plays a role in decreasing cellular protoporphyrin IX levels. Zhou, S., Zong, Y., Ney, P.A., Nair, G., Stewart, C.F., Sorrentino, B.P. Blood (2005)
- Altered hepatobiliary disposition of 5 (and 6)-carboxy-2',7'-dichlorofluorescein in Abcg2 (Bcrp1) and Abcc2 (Mrp2) knockout mice. Nezasa, K., Tian, X., Zamek-Gliszczynski, M.J., Patel, N.J., Raub, T.J., Brouwer, K.L. Drug Metab. Dispos. (2006)
- Lack of improvement of oral absorption of ME3277 by prodrug formation is ascribed to the intestinal efflux mediated by breast cancer resistant protein (BCRP/ABCG2). Kondo, C., Onuki, R., Kusuhara, H., Suzuki, H., Suzuki, M., Okudaira, N., Kojima, M., Ishiwata, K., Jonker, J.W., Sugiyama, Y. Pharm. Res. (2005)
- In vitro and in vivo evaluation of WK-X-34, a novel inhibitor of P-glycoprotein and BCRP, using radio imaging techniques. Jekerle, V., Klinkhammer, W., Scollard, D.A., Breitbach, K., Reilly, R.M., Piquette-Miller, M., Wiese, M. Int. J. Cancer (2006)