Gene Review:
Gpc3 - glypican 3
Mus musculus
Synonyms:
Glypican-3, OCI-5
- Inhibition of invasion and metastasis by glypican-3 in a syngeneic breast cancer model. Peters, M.G., Farías, E., Colombo, L., Filmus, J., Puricelli, L., Bal de Kier Joffé, E. Breast Cancer Res. Treat. (2003)
- Embryonic stem cell-derived dendritic cells expressing glypican-3, a recently identified oncofetal antigen, induce protective immunity against highly metastatic mouse melanoma, B16-F10. Motomura, Y., Senju, S., Nakatsura, T., Matsuyoshi, H., Hirata, S., Monji, M., Komori, H., Fukuma, D., Baba, H., Nishimura, Y. Cancer Res. (2006)
- Glypican-3 expression is silenced in human breast cancer. Xiang, Y.Y., Ladeda, V., Filmus, J. Oncogene (2001)
- Altered hematopoiesis in glypican-3-deficient mice results in decreased osteoclast differentiation and a delay in endochondral ossification. Viviano, B.L., Silverstein, L., Pflederer, C., Paine-Saunders, S., Mills, K., Saunders, S. Dev. Biol. (2005)
- Glypican-3 modulates BMP- and FGF-mediated effects during renal branching morphogenesis. Grisaru, S., Cano-Gauci, D., Tee, J., Filmus, J., Rosenblum, N.D. Dev. Biol. (2001)
- glypican-3 controls cellular responses to Bmp4 in limb patterning and skeletal development. Paine-Saunders, S., Viviano, B.L., Zupicich, J., Skarnes, W.C., Saunders, S. Dev. Biol. (2000)
- Glypican-3 modulates inhibitory Bmp2-Smad signaling to control renal development in vivo. Hartwig, S., Hu, M.C., Cella, C., Piscione, T., Filmus, J., Rosenblum, N.D. Mech. Dev. (2005)
- Overgrowth of a mouse model of the Simpson-Golabi-Behmel syndrome is independent of IGF signaling. Chiao, E., Fisher, P., Crisponi, L., Deiana, M., Dragatsis, I., Schlessinger, D., Pilia, G., Efstratiadis, A. Dev. Biol. (2002)
- Glypicans are differentially expressed during patterning and neurogenesis of early mouse brain. Luxardi, G., Galli, A., Forlani, S., Lawson, K., Maina, F., Dono, R. Biochem. Biophys. Res. Commun. (2007)
- Overgrowth syndromes and genomic imprinting: from mouse to man. Li, M., Squire, J.A., Weksberg, R. Clin. Genet. (1998)
- Regulatory variation at glypican-3 underlies a major growth QTL in mice. Oliver, F., Christians, J.K., Liu, X., Rhind, S., Verma, V., Davison, C., Brown, S.D., Denny, P., Keightley, P.D. PLoS Biol. (2005)
- Glypican-3 is a novel inhibitor of insulin-like growth factor signaling. Filmus, J., Song, H., Shi, W., Duenas Gonzalez, A., Kaya, M., Cano-Gauci, D. Medicina (B Aires) (1999)