Gene Review:
Grb10 - growth factor receptor bound protein 10
Mus musculus
Synonyms:
5730571D09Rik, AI325020, GRB10 adapter protein, Growth factor receptor-bound protein 10, Maternally expressed gene 1 protein, ...
- The adapter protein Grb10 associates preferentially with the insulin receptor as compared with the IGF-I receptor in mouse fibroblasts. Laviola, L., Giorgino, F., Chow, J.C., Baquero, J.A., Hansen, H., Ooi, J., Zhu, J., Riedel, H., Smith, R.J. J. Clin. Invest. (1997)
- Disruption of the imprinted Grb10 gene leads to disproportionate overgrowth by an Igf2-independent mechanism. Charalambous, M., Smith, F.M., Bennett, W.R., Crew, T.E., Mackenzie, F., Ward, A. Proc. Natl. Acad. Sci. U.S.A. (2003)
- Identification of the Meg1/Grb10 imprinted gene on mouse proximal chromosome 11, a candidate for the Silver-Russell syndrome gene. Miyoshi, N., Kuroiwa, Y., Kohda, T., Shitara, H., Yonekawa, H., Kawabe, T., Hasegawa, H., Barton, S.C., Surani, M.A., Kaneko-Ishino, T., Ishino, F. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Two novel proteins that are linked to insulin-like growth factor (IGF-I) receptors by the Grb10 adapter and modulate IGF-I signaling. Giovannone, B., Lee, E., Laviola, L., Giorgino, F., Cleveland, K.A., Smith, R.J. J. Biol. Chem. (2003)
- The adapter protein GRB10 is an endogenous negative regulator of insulin-like growth factor signaling. Dufresne, A.M., Smith, R.J. Endocrinology (2005)
- Role for the adaptor protein Grb10 in the activation of Akt. Jahn, T., Seipel, P., Urschel, S., Peschel, C., Duyster, J. Mol. Cell. Biol. (2002)
- Growth factor receptor-binding protein 10 (Grb10) as a partner of phosphatidylinositol 3-kinase in metabolic insulin action. Deng, Y., Bhattacharya, S., Swamy, O.R., Tandon, R., Wang, Y., Janda, R., Riedel, H. J. Biol. Chem. (2003)
- The cloning of Grb10 reveals a new family of SH2 domain proteins. Ooi, J., Yajnik, V., Immanuel, D., Gordon, M., Moskow, J.J., Buchberg, A.M., Margolis, B. Oncogene (1995)
- Ligand activation of ELK receptor tyrosine kinase promotes its association with Grb10 and Grb2 in vascular endothelial cells. Stein, E., Cerretti, D.P., Daniel, T.O. J. Biol. Chem. (1996)
- Grb10 and Grb14: enigmatic regulators of insulin action--and more? Holt, L.J., Siddle, K. Biochem. J. (2005)
- Distinct Grb10 domain requirements for effects on glucose uptake and insulin signaling. Mori, K., Giovannone, B., Smith, R.J. Mol. Cell. Endocrinol. (2005)
- Mice with a disruption of the imprinted Grb10 gene exhibit altered body composition, glucose homeostasis, and insulin signaling during postnatal life. Smith, F.M., Holt, L.J., Garfield, A.S., Charalambous, M., Koumanov, F., Perry, M., Bazzani, R., Sheardown, S.A., Hegarty, B.D., Lyons, R.J., Cooney, G.J., Daly, R.J., Ward, A. Mol. Cell. Biol. (2007)
- Peripheral disruption of the Grb10 gene enhances insulin signaling and sensitivity in vivo. Wang, L., Balas, B., Christ-Roberts, C.Y., Kim, R.Y., Ramos, F.J., Kikani, C.K., Li, C., Deng, C., Reyna, S., Musi, N., Dong, L.Q., DeFronzo, R.A., Liu, F. Mol. Cell. Biol. (2007)
- mGrb10 interacts with Nedd4. Morrione, A., Plant, P., Valentinis, B., Staub, O., Kumar, S., Rotin, D., Baserga, R. J. Biol. Chem. (1999)
- Negative regulation of insulin-stimulated mitogen-activated protein kinase signaling by Grb10. Langlais, P., Dong, L.Q., Ramos, F.J., Hu, D., Li, Y., Quon, M.J., Liu, F. Mol. Endocrinol. (2004)
- Meg1/Grb10 overexpression causes postnatal growth retardation and insulin resistance via negative modulation of the IGF1R and IR cascades. Shiura, H., Miyoshi, N., Konishi, A., Wakisaka-Saito, N., Suzuki, R., Muguruma, K., Kohda, T., Wakana, S., Yokoyama, M., Ishino, F., Kaneko-Ishino, T. Biochem. Biophys. Res. Commun. (2005)
- Association of a redefined proximal mouse chromosome 11 imprinting region and U2afbp-rs/U2af1-rs1 expression. Cattanach, B.M., Shibata, H., Hayashizaki, Y., Townsend, K.M., Ball, S., Beechey, C.V. Cytogenet. Cell Genet. (1998)
- Role of DNA methylation and histone h3 lysine 27 methylation in tissue-specific imprinting of mouse grb10. Yamasaki-Ishizaki, Y., Kayashima, T., Mapendano, C.K., Soejima, H., Ohta, T., Masuzaki, H., Kinoshita, A., Urano, T., Yoshiura, K., Matsumoto, N., Ishimaru, T., Mukai, T., Niikawa, N., Kishino, T. Mol. Cell. Biol. (2007)