Gene Review:
GRB10 - growth factor receptor-bound protein 10
Homo sapiens
Synonyms:
GRB-IR, GRB10 adapter protein, GRBIR, Grb-10, Growth factor receptor-bound protein 10, ...
- Conserved methylation imprints in the human and mouse GRB10 genes with divergent allelic expression suggests differential reading of the same mark. Arnaud, P., Monk, D., Hitchins, M., Gordon, E., Dean, W., Beechey, C.V., Peters, J., Craigen, W., Preece, M., Stanier, P., Moore, G.E., Kelsey, G. Hum. Mol. Genet. (2003)
- Genomic structure of the gene for the SH2 and pleckstrin homology domain-containing protein GRB10 and evaluation of its role in Hirschsprung disease. Angrist, M., Bolk, S., Bentley, K., Nallasamy, S., Halushka, M.K., Chakravarti, A. Oncogene (1998)
- Up-regulation of growth factor receptor-bound protein 10 in cervical squamous cell carcinoma. Okino, K., Konishi, H., Doi, D., Yoneyama, K., Ota, Y., Jin, E., Kawanami, O., Takeshita, T. Oncol. Rep. (2005)
- Linear growth in response to growth hormone treatment in children with short stature associated with intrauterine growth retardation: the National Cooperative Growth Study experience. Chernausek, S.D., Breen, T.J., Frank, G.R. J. Pediatr. (1996)
- An early decrease in interphotoreceptor retinoid-binding protein gene expression in Abyssinian cats homozygous for hereditary rod-cone degeneration. Wiggert, B., van Veen, T., Kutty, G., Lee, L., Nickerson, J., Si, J.S., Nilsson, S.E., Chader, G.J., Narfström, K. Cell Tissue Res. (1994)
- Cardiac risk assessment: matching intensity of therapy to risk. Vesely, M.R., Kelemen, M.D. Cardiology clinics. (2006)
- Assignment of multiple endocrine neoplasia type 2A to chromosome 10 by linkage. Simpson, N.E., Kidd, K.K., Goodfellow, P.J., McDermid, H., Myers, S., Kidd, J.R., Jackson, C.E., Duncan, A.M., Farrer, L.A., Brasch, K. Nature (1987)
- Endogenous IRBP can be dispensable for generation of natural CD4+CD25+ regulatory T cells that protect from IRBP-induced retinal autoimmunity. Grajewski, R.S., Silver, P.B., Agarwal, R.K., Su, S.B., Chan, C.C., Liou, G.I., Caspi, R.R. J. Exp. Med. (2006)
- Spontaneous autoimmunity prevented by thymic expression of a single self-antigen. Devoss, J., Hou, Y., Johannes, K., Lu, W., Liou, G.I., Rinn, J., Chang, H., Caspi, R., Fong, L., Anderson, M.S. J. Exp. Med. (2006)
- A humanized model of experimental autoimmune uveitis in HLA class II transgenic mice. Pennesi, G., Mattapallil, M.J., Sun, S.H., Avichezer, D., Silver, P.B., Karabekian, Z., David, C.S., Hargrave, P.A., McDowell, J.H., Smith, W.C., Wiggert, B., Donoso, L.A., Chan, C.C., Caspi, R.R. J. Clin. Invest. (2003)
- Butyrate enhances the synthesis of interphotoreceptor retinoid-binding protein (IRBP) by Y-79 human retinoblastoma cells. Kyritsis, A.P., Wiggert, B., Lee, L., Chader, G.J. J. Cell. Physiol. (1985)
- Regulation of interphotoreceptor retinoid-binding protein (IRBP) gene expression by cAMP in differentiated retinoblastoma cells. El-Remessy, A.E., Rabie, A.M., El-Shishtawy, M.M., Eissa, L.A., Liou, G.I. Mol. Vis. (2000)
- Variation in seasonal ultrastructure of sexual granules in the renal sexual segment of the Northern Water Snake, Nerodia sipedon sipedon. Krohmer, R.W. J. Morphol. (2004)
- Identification of the Meg1/Grb10 imprinted gene on mouse proximal chromosome 11, a candidate for the Silver-Russell syndrome gene. Miyoshi, N., Kuroiwa, Y., Kohda, T., Shitara, H., Yonekawa, H., Kawabe, T., Hasegawa, H., Barton, S.C., Surani, M.A., Kaneko-Ishino, T., Ishino, F. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Imprinting of human GRB10 and its mutations in two patients with Russell-Silver syndrome. Yoshihashi, H., Maeyama, K., Kosaki, R., Ogata, T., Tsukahara, M., Goto, Y., Hata, J., Matsuo, N., Smith, R.J., Kosaki, K. Am. J. Hum. Genet. (2000)
- Human GRB10 is imprinted and expressed from the paternal and maternal allele in a highly tissue- and isoform-specific fashion. Blagitko, N., Mergenthaler, S., Schulz, U., Wollmann, H.A., Craigen, W., Eggermann, T., Ropers, H.H., Kalscheuer, V.M. Hum. Mol. Genet. (2000)
- Lack of association of birth size with polymorphisms of two imprinted genes, IGF2R and GRB10. Kukuvitis, A., Georgiou, I., Syrrou, M., Andronikou, S., Dickerman, Z., Islam, A., McCann, J., Polychronakos, C. Journal of pediatric endocrinology & metabolism : JPEM. (2004)
- Duplication of 7p11.2-p13, including GRB10, in Silver-Russell syndrome. Monk, D., Wakeling, E.L., Proud, V., Hitchins, M., Abu-Amero, S.N., Stanier, P., Preece, M.A., Moore, G.E. Am. J. Hum. Genet. (2000)
- Maternal repression of the human GRB10 gene in the developing central nervous system; evaluation of the role for GRB10 in Silver-Russell syndrome. Hitchins, M.P., Monk, D., Bell, G.M., Ali, Z., Preece, M.A., Stanier, P., Moore, G.E. Eur. J. Hum. Genet. (2001)
- The Ret receptor protein tyrosine kinase associates with the SH2-containing adapter protein Grb10. Pandey, A., Duan, H., Di Fiore, P.P., Dixit, V.M. J. Biol. Chem. (1995)
- Structural basis for dimerization of the Grb10 Src homology 2 domain. Implications for ligand specificity. Stein, E.G., Ghirlando, R., Hubbard, S.R. J. Biol. Chem. (2003)
- Identification of Grb10 as a direct substrate for members of the Src tyrosine kinase family. Langlais, P., Dong, L.Q., Hu, D., Liu, F. Oncogene (2000)
- Phosphorylation of Grb10 by mitogen-activated protein kinase: identification of Ser150 and Ser476 of human Grb10zeta as major phosphorylation sites. Langlais, P., Wang, C., Dong, L.Q., Carroll, C.A., Weintraub, S.T., Liu, F. Biochemistry (2005)
- The SH2-containing adapter protein GRB10 interacts with BCR-ABL. Bai, R.Y., Jahn, T., Schrem, S., Munzert, G., Weidner, K.M., Wang, J.Y., Duyster, J. Oncogene (1998)
- Grb10 interacts differentially with the insulin receptor, insulin-like growth factor I receptor, and epidermal growth factor receptor via the Grb10 Src homology 2 (SH2) domain and a second novel domain located between the pleckstrin homology and SH2 domains. He, W., Rose, D.W., Olefsky, J.M., Gustafson, T.A. J. Biol. Chem. (1998)
- Localization of endogenous Grb10 to the mitochondria and its interaction with the mitochondrial-associated Raf-1 pool. Nantel, A., Huber, M., Thomas, D.Y. J. Biol. Chem. (1999)
- Grb10 prevents Nedd4-mediated vascular endothelial growth factor receptor-2 degradation. Murdaca, J., Treins, C., Monthouël-Kartmann, M.N., Pontier-Bres, R., Kumar, S., Van Obberghen, E., Giorgetti-Peraldi, S. J. Biol. Chem. (2004)
- Grb10 adapter protein as regulator of insulin-like growth factor receptor signaling. Morrione, A. J. Cell. Physiol. (2003)
- The BPS domain of Grb10 inhibits the catalytic activity of the insulin and IGF1 receptors. Stein, E.G., Gustafson, T.A., Hubbard, S.R. FEBS Lett. (2001)
- Duplication of 7p12.1-p13, including GRB10 and IGFBP1, in a mother and daughter with features of Silver-Russell syndrome. Joyce, C.A., Sharp, A., Walker, J.M., Bullman, H., Temple, I.K. Hum. Genet. (1999)
- Detection of maternal uniparental disomy at the two imprinted genes on chromosome 7, GRB10 and PEG1/MEST, in a Silver-Russell syndrome patient using methylation-specific PCR assays. Kim, Y., Kim, S.S., Kim, G., Park, S., Park, I.S., Yoo, H.W. Clin. Genet. (2005)
- Possible parent-of-origin effect of Dopa decarboxylase in susceptibility to bipolar affective disorder. Børglum, A.D., Kirov, G., Craddock, N., Mors, O., Muir, W., Murray, V., McKee, I., Collier, D.A., Ewald, H., Owen, M.J., Blackwood, D., Kruse, T.A. Am. J. Med. Genet. B Neuropsychiatr. Genet. (2003)
- Evidence against GRB10 as the gene responsible for Silver-Russell syndrome. McCann, J.A., Zheng, H., Islam, A., Goodyer, C.G., Polychronakos, C. Biochem. Biophys. Res. Commun. (2001)
- Grb10, a positive, stimulatory signaling adapter in platelet-derived growth factor BB-, insulin-like growth factor I-, and insulin-mediated mitogenesis. Wang, J., Dai, H., Yousaf, N., Moussaif, M., Deng, Y., Boufelliga, A., Swamy, O.R., Leone, M.E., Riedel, H. Mol. Cell. Biol. (1999)
- Retroviral gene therapy with an immunoglobulin-antigen fusion construct protects from experimental autoimmune uveitis. Agarwal, R.K., Kang, Y., Zambidis, E., Scott, D.W., Chan, C.C., Caspi, R.R. J. Clin. Invest. (2000)