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Klc1  -  kinesin light chain 1

Mus musculus

Synonyms: AI874768, KLC 1, Kinesin light chain 1, Kns2
 
 
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Disease relevance of Klc1

 

Psychiatry related information on Klc1

 

High impact information on Klc1

 

Biological context of Klc1

 

Anatomical context of Klc1

 

Physical interactions of Klc1

 

Other interactions of Klc1

  • Mutations of Leu-280, Leu-287, Val-294, and Leu-301 within this domain of KLC1 disrupted its ability to associate with JLP [5].

References

  1. Kinesin-2 and photoreceptor cell death: requirement of motor subunits. Jimeno, D., Lillo, C., Roberts, E.A., Goldstein, L.S., Williams, D.S. Exp. Eye Res. (2006) [Pubmed]
  2. Defective kinesin heavy chain behavior in mouse kinesin light chain mutants. Rahman, A., Kamal, A., Roberts, E.A., Goldstein, L.S. J. Cell Biol. (1999) [Pubmed]
  3. Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP. Kamal, A., Almenar-Queralt, A., LeBlanc, J.F., Roberts, E.A., Goldstein, L.S. Nature (2001) [Pubmed]
  4. Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors. Liu, A., Wang, B., Niswander, L.A. Development (2005) [Pubmed]
  5. JLP associates with kinesin light chain 1 through a novel leucine zipper-like domain. Nguyen, Q., Lee, C.M., Le, A., Reddy, E.P. J. Biol. Chem. (2005) [Pubmed]
  6. Release of kinesin from vesicles by hsc70 and regulation of fast axonal transport. Tsai, M.Y., Morfini, G., Szebenyi, G., Brady, S.T. Mol. Biol. Cell (2000) [Pubmed]
  7. Analysis of Kinesin-2 Function in Photoreceptor Cells Using Synchronous Cre-loxP Knockout of Kif3a with RHO-Cre. Jimeno, D., Feiner, L., Lillo, C., Teofilo, K., Goldstein, L.S., Pierce, E.A., Williams, D.S. Invest. Ophthalmol. Vis. Sci. (2006) [Pubmed]
  8. Kinesin light-chain KLC3 expression in testis is restricted to spermatids. Junco, A., Bhullar, B., Tarnasky, H.A., van der Hoorn, F.A. Biol. Reprod. (2001) [Pubmed]
  9. Phosphotransferases associated with the regulation of kinesin motor activity. Lindesmith, L., McIlvain, J.M., Argon, Y., Sheetz, M.P. J. Biol. Chem. (1997) [Pubmed]
 
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