The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

Klc1  -  kinesin light chain 1

Mus musculus

Synonyms: AI874768, KLC 1, Kinesin light chain 1, Kns2
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Klc1


Psychiatry related information on Klc1


High impact information on Klc1


Biological context of Klc1


Anatomical context of Klc1


Physical interactions of Klc1


Other interactions of Klc1

  • Mutations of Leu-280, Leu-287, Val-294, and Leu-301 within this domain of KLC1 disrupted its ability to associate with JLP [5].


  1. Kinesin-2 and photoreceptor cell death: requirement of motor subunits. Jimeno, D., Lillo, C., Roberts, E.A., Goldstein, L.S., Williams, D.S. Exp. Eye Res. (2006) [Pubmed]
  2. Defective kinesin heavy chain behavior in mouse kinesin light chain mutants. Rahman, A., Kamal, A., Roberts, E.A., Goldstein, L.S. J. Cell Biol. (1999) [Pubmed]
  3. Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP. Kamal, A., Almenar-Queralt, A., LeBlanc, J.F., Roberts, E.A., Goldstein, L.S. Nature (2001) [Pubmed]
  4. Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors. Liu, A., Wang, B., Niswander, L.A. Development (2005) [Pubmed]
  5. JLP associates with kinesin light chain 1 through a novel leucine zipper-like domain. Nguyen, Q., Lee, C.M., Le, A., Reddy, E.P. J. Biol. Chem. (2005) [Pubmed]
  6. Release of kinesin from vesicles by hsc70 and regulation of fast axonal transport. Tsai, M.Y., Morfini, G., Szebenyi, G., Brady, S.T. Mol. Biol. Cell (2000) [Pubmed]
  7. Analysis of Kinesin-2 Function in Photoreceptor Cells Using Synchronous Cre-loxP Knockout of Kif3a with RHO-Cre. Jimeno, D., Feiner, L., Lillo, C., Teofilo, K., Goldstein, L.S., Pierce, E.A., Williams, D.S. Invest. Ophthalmol. Vis. Sci. (2006) [Pubmed]
  8. Kinesin light-chain KLC3 expression in testis is restricted to spermatids. Junco, A., Bhullar, B., Tarnasky, H.A., van der Hoorn, F.A. Biol. Reprod. (2001) [Pubmed]
  9. Phosphotransferases associated with the regulation of kinesin motor activity. Lindesmith, L., McIlvain, J.M., Argon, Y., Sheetz, M.P. J. Biol. Chem. (1997) [Pubmed]
WikiGenes - Universities