Gene Review:
daf-16 - Protein DAF-16
Caenorhabditis elegans
- Hormesis in Caenorhabditis elegans dauer-defective mutants. Cypser, J.R., Johnson, T.E. Biogerontology. (2003)
- daf-16 protects the nematode Caenorhabditis elegans during food deprivation. Henderson, S.T., Bonafè, M., Johnson, T.E. J. Gerontol. A Biol. Sci. Med. Sci. (2006)
- Long lifespan in worms with long telomeric DNA. Joeng, K.S., Song, E.J., Lee, K.J., Lee, J. Nat. Genet. (2004)
- Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan. Libina, N., Berman, J.R., Kenyon, C. Cell (2003)
- Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Tissenbaum, H.A., Guarente, L. Nature (2001)
- A C. elegans mutant that lives twice as long as wild type. Kenyon, C., Chang, J., Gensch, E., Rudner, A., Tabtiang, R. Nature (1993)
- AKT-1 Regulates DNA-Damage-Induced Germline Apoptosis in C. elegans. Quevedo, C., Kaplan, D.R., Derry, W.B. Curr. Biol. (2007)
- Activated AKT/PKB signaling in C. elegans uncouples temporally distinct outputs of DAF-2/insulin-like signaling. Gami, M.S., Iser, W.B., Hanselman, K.B., Wolkow, C.A. BMC Dev. Biol. (2006)
- Uncoupling of pathways that promote postmitotic life span and apoptosis from replicative immortality of Caenorhabditis elegans germ cells. Ahmed, S. Aging Cell (2006)
- Mutations in chemosensory cilia cause resistance to paraquat in nematode Caenorhabditis elegans. Fujii, M., Matsumoto, Y., Tanaka, N., Miki, K., Suzuki, T., Ishii, N., Ayusawa, D. J. Biol. Chem. (2004)
- DAF-16/FOXO regulates transcription of cki-1/Cip/Kip and repression of lin-4 during C. elegans L1 arrest. Baugh, L.R., Sternberg, P.W. Curr. Biol. (2006)
- daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. Lin, K., Dorman, J.B., Rodan, A., Kenyon, C. Science (1997)
- A defect in the activity of Delta6 and Delta5 desaturases may be a factor predisposing to the development of insulin resistance syndrome. Das, U.N. Prostaglandins Leukot. Essent. Fatty Acids (2005)
- A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span. Viswanathan, M., Kim, S.K., Berdichevsky, A., Guarente, L. Dev. Cell (2005)
- daf-2, daf-16 and daf-23: genetically interacting genes controlling Dauer formation in Caenorhabditis elegans. Gottlieb, S., Ruvkun, G. Genetics (1994)
- An insulin-like signaling pathway affects both longevity and reproduction in Caenorhabditis elegans. Tissenbaum, H.A., Ruvkun, G. Genetics (1998)
- The p38 signal transduction pathway participates in the oxidative stress-mediated translocation of DAF-16 to Caenorhabditis elegans nuclei. Kondo, M., Yanase, S., Ishii, T., Hartman, P.S., Matsumoto, K., Ishii, N. Mech. Ageing Dev. (2005)
- Genetic analysis of chemosensory control of dauer formation in Caenorhabditis elegans. Vowels, J.J., Thomas, J.H. Genetics (1992)
- DAF-16-dependent and independent expression targets of DAF-2 insulin receptor-like pathway in Caenorhabditis elegans include FKBPs. Yu, H., Larsen, P.L. J. Mol. Biol. (2001)
- Apparent uncoupling of energy production and consumption in long-lived Clk mutants of Caenorhabditis elegans. Braeckman, B.P., Houthoofd, K., De Vreese, A., Vanfleteren, J.R. Curr. Biol. (1999)
- Adaptive responses to oxidative damage in three mutants of Caenorhabditis elegans (age-1, mev-1 and daf-16) that affect life span. Yanase, S., Yasuda, K., Ishii, N. Mech. Ageing Dev. (2002)
- The OLD-1 positive regulator of longevity and stress resistance is under DAF-16 regulation in Caenorhabditis elegans. Murakami, S., Johnson, T.E. Curr. Biol. (2001)
- Delayed development and lifespan extension as features of metabolic lifestyle alteration in C. elegans under dietary restriction. Szewczyk, N.J., Udranszky, I.A., Kozak, E., Sunga, J., Kim, S.K., Jacobson, L.A., Conley, C.A. J. Exp. Biol. (2006)