Gene Review:
Six1 - sine oculis-related homeobox 1
Mus musculus
Synonyms:
BB138287, Homeobox protein SIX1, Sine oculis homeobox homolog 1
- The role of Six1 in mammalian auditory system development. Zheng, W., Huang, L., Wei, Z.B., Silvius, D., Tang, B., Xu, P.X. Development (2003)
- Thymus, kidney and craniofacial abnormalities in Six 1 deficient mice. Laclef, C., Souil, E., Demignon, J., Maire, P. Mech. Dev. (2003)
- The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1. Coletta, R.D., Christensen, K., Reichenberger, K.J., Lamb, J., Micomonaco, D., Huang, L., Wolf, D.M., Müller-Tidow, C., Golub, T.R., Kawakami, K., Ford, H.L. Proc. Natl. Acad. Sci. U.S.A. (2004)
- The homeoprotein six1 transcriptionally activates multiple protumorigenic genes but requires ezrin to promote metastasis. Yu, Y., Davicioni, E., Triche, T.J., Merlino, G. Cancer Res. (2006)
- Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators. Yu, Y., Khan, J., Khanna, C., Helman, L., Meltzer, P.S., Merlino, G. Nat. Med. (2004)
- Expression of myogenin during embryogenesis is controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding site. Spitz, F., Demignon, J., Porteu, A., Kahn, A., Concordet, J.P., Daegelen, D., Maire, P. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Six1 and Six4 homeoproteins are required for Pax3 and Mrf expression during myogenesis in the mouse embryo. Grifone, R., Demignon, J., Houbron, C., Souil, E., Niro, C., Seller, M.J., Hamard, G., Maire, P. Development (2005)
- Altered myogenesis in Six1-deficient mice. Laclef, C., Hamard, G., Demignon, J., Souil, E., Houbron, C., Maire, P. Development (2003)
- Six1 is required for the early organogenesis of mammalian kidney. Xu, P.X., Zheng, W., Huang, L., Maire, P., Laclef, C., Silvius, D. Development (2003)
- Patterning of the third pharyngeal pouch into thymus/parathyroid by Six and Eya1. Zou, D., Silvius, D., Davenport, J., Grifone, R., Maire, P., Xu, P.X. Dev. Biol. (2006)
- Six1 is not involved in limb tendon development, but is expressed in limb connective tissue under Shh regulation. Bonnin, M.A., Laclef, C., Blaise, R., Eloy-Trinquet, S., Relaix, F., Maire, P., Duprez, D. Mech. Dev. (2005)