Gene Review:
FFAR2 - free fatty acid receptor 2
Homo sapiens
Synonyms:
FFA2, FFA2R, Free fatty acid receptor 2, G-protein coupled receptor 43, GPCR43, ...
- Short-chain fatty acids induce acute phosphorylation of the p38 mitogen-activated protein kinase/heat shock protein 27 pathway via GPR43 in the MCF-7 human breast cancer cell line. Yonezawa, T., Kobayashi, Y., Obara, Y. Cell. Signal. (2007)
- Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation. Le Poul, E., Loison, C., Struyf, S., Springael, J.Y., Lannoy, V., Decobecq, M.E., Brezillon, S., Dupriez, V., Vassart, G., Van Damme, J., Parmentier, M., Detheux, M. J. Biol. Chem. (2003)
- The G-protein-coupled receptor 40 family (GPR40-GPR43) and its role in nutrient sensing. Covington, D.K., Briscoe, C.A., Brown, A.J., Jayawickreme, C.K. Biochem. Soc. Trans. (2006)
- LSSIG is a novel murine leukocyte-specific GPCR that is induced by the activation of STAT3. Senga, T., Iwamoto, S., Yoshida, T., Yokota, T., Adachi, K., Azuma, E., Hamaguchi, M., Iwamoto, T. Blood (2003)
- The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids. Brown, A.J., Goldsworthy, S.M., Barnes, A.A., Eilert, M.M., Tcheang, L., Daniels, D., Muir, A.I., Wigglesworth, M.J., Kinghorn, I., Fraser, N.J., Pike, N.B., Strum, J.C., Steplewski, K.M., Murdock, P.R., Holder, J.C., Marshall, F.H., Szekeres, P.G., Wilson, S., Ignar, D.M., Foord, S.M., Wise, A., Dowell, S.J. J. Biol. Chem. (2003)
- The relationship between the effects of short-chain fatty acids on intestinal motility in vitro and GPR43 receptor activation. Dass, N.B., John, A.K., Bassil, A.K., Crumbley, C.W., Shehee, W.R., Maurio, F.P., Moore, G.B., Taylor, C.M., Sanger, G.J. Neurogastroenterol. Motil. (2007)
- Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids. Nilsson, N.E., Kotarsky, K., Owman, C., Olde, B. Biochem. Biophys. Res. Commun. (2003)
- Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine. Karaki, S., Mitsui, R., Hayashi, H., Kato, I., Sugiya, H., Iwanaga, T., Furness, J.B., Kuwahara, A. Cell Tissue Res. (2006)