Disease relevance of RHE_PD00269

• Since this is the region at which Rhizobium binding occurs and at which nodulation probably is initiated, all the reported observations on the root lectin are consistent with its proposed role in the specific interaction of the developing soybean with its symbiont [1].
• NodD1 is a member of the NodD family of LysR-type transcriptional regulators that mediates the expression of nodulation (nod) genes in the soil bacterium Sinorhizobium meliloti [2].
• Nodulation of actinorhizal plants (Alnus rubra Bong, and others) by isolated Frankia strains occurred either at a low frequency or not at all under axenic conditions [3].
• Four strains of Pseudomonas cepacia also promoted nodulation [3].
• Eleven strains of Rhizobium and five strains of Bradyrhizobium were examined for their viability as well nodulation and nitrogen fixation ability after storage under different conditions for two years [4].

High impact information on RHE_PD00269

• These mutants were complemented for nodulation and for the syntheses of these polysaccharides by plasmid pMP2603 [5].
• Rhizobium leguminosarum bv. viciae Exo- mutant strains RBL5523,exo7::Tn5,RBL5523,exo8::Tn5 and RBL5523,exo52::Tn5 are affected in nodulation and in the syntheses of lipopolysaccharide, capsular polysaccharide, and exocellular polysaccharide [5].
• Plasmid pRleVF39d carries nodulation and nitrogen fixation genes [6].
• The Ethylene-Insensitive sickle Mutant of Medicago truncatula Shows Altered Auxin Transport Regulation during Nodulation [7].
• MtCPK3 mRNA and protein were also up-regulated by cytokinin treatment, a hormone linked to the regulation of cortical cell division and other nodulation-related responses [8].

Chemical compound and disease context of RHE_PD00269

• This reduction in nodulation with increasing Cu(2+) activity was associated with an inhibition of root hair formation in treatments containing > or =0.77 microM Cu(2+), rather than to a reduction in the size of the Rhizobium population [9].
• Dual infections of Glycine max with VA endophytes and Rhizobium, compared with Rhizobium alone, increased the number and weight of nodules significantly in natural field soil and obviated the need of phosphate application for successful nodulation [10].

Biological context of RHE_PD00269

• Subsequently, the phylogeny of nodulating plants is described and a comparison is made between several aspects of legume and actinorhizal nodulation [11].
• Analysis of Nod-factor-induced calcium signaling in root hairs of symbiotically defective mutants of Lotus japonicus [12].
• This suggests that a deficiency in signal transduction is the reason for nodulation failure in the mature root [13].
• We tested whether the inability to form nodules in the mature root is due to a lack of plant flavonoids to induce the bacterial genes required for nodulation or a failure of mature cortical cells to respond to Rhizobium spp [13].
• The synthesis of periplasmic beta(1-2)glucan is required for crown gall tumor formation by Agrobacterium tumefaciens and for effective nodulation of alfalfa by Rhizobium meliloti [14].

Anatomical context of RHE_PD00269

• In contrast to the R. fredii host-inducible gene, expression of ORF3 is not induced in the presence of Phaseolus vulgaris root exudates or by specific flavonoids, able to induce nodulation genes in R. l. bv. phaseoli [15].
• In this work the influence of the nodulation of pea (Pisum sativum L.) plants on the oxidative metabolism of different leaf organelles from young and senescent plants was studied [16].

Associations of RHE_PD00269 with chemical compounds

• We studied the ethylene-insensitive, hypernodulating mutant, sickle (skl), to investigate the interaction of ethylene with auxin transport during root nodulation in Medicago truncatula [7].
• Using ethylmethane sulfonate mutagenesis as a tool to identify plant genes involved in symbiotic nodule development, we have isolated and analyzed five nodulation mutants, Ljsym74-3, Ljsym79-2, Ljsym79-3, Ljsym80, and Ljsym82, from the model legume Lotus japonicus [17].
• A highly upregulated gene in bacteroids, mlr5932 (encoding 1-aminocyclopropane-1-carboxylate deaminase), was disrupted and was confirmed to be involved in nodulation enhancement, indicating that disruption of highly expressed genes is a useful strategy for exploring novel gene functions in symbiosis [18].
• Metabolic engineering of rice with soybean isoflavone synthase for promoting nodulation gene expression in rhizobia [19].
• The effect of Cu(2+) on nodulation of cowpea (Vigna unguiculata (L.) Walp. cv. Caloona) was examined in a dilute solution culture system utilising a cation exchange resin to buffer solution Cu(2+) [9].

Analytical, diagnostic and therapeutic context of RHE_PD00269

• Using a dual dye ratiometric calcium imaging technique, we have shown that 10 nM Nod factor added to roots of Lotus japonicus seedlings induces an intracellular calcium increase (calcium flux) that precedes oscillations in intracellular calcium (calcium spiking) [12].

References