Gene Review:
HPSE2 - heparanase 2 (inactive)
Homo sapiens
Synonyms:
HPA2, HPR2, Hpa2, Inactive heparanase-2, UFS, ...
- Localization of the platelet-specific HPA-2 (Ko) alloantigens on the N-terminal globular fragment of platelet glycoprotein Ib alpha. Kuijpers, R.W., Ouwehand, W.H., Bleeker, P.M., Christie, D., von dem Borne, A.E. Blood (1992)
- Threonine-145/methionine-145 variants of baculovirus produced recombinant ligand binding domain of GPIbalpha express HPA-2 epitopes and show equal binding of von Willebrand factor. Li, C.Q., Garner, S.F., Davies, J., Smethurst, P.A., Wardell, M.R., Ouwehand, W.H. Blood (2000)
- Stepwise cloning and molecular characterization of the HgiDI restriction-modification system from Herpetosiphon giganteus Hpa2. Düsterhöft, A., Erdmann, D., Kröger, M. Nucleic Acids Res. (1991)
- A common polymorphism flanking the ATG initiator codon of GPIb alpha does not affect expression and is not a major risk factor for arterial thrombosis. Corral, J., Lozano, M.L., González-Conejero, R., Martínez, C., Iniesta, J.A., Rivera, J., Vicente, V. Thromb. Haemost. (2000)
- Alloimmunization against human platelet antigen 2 (HPA2) in a series of multi-transfused beta-thalassemia patients. Tazzari, P.L., Ricci, F., Tassi, C., Bontadini, A., Fruet, F., Conte, R. Haematologica (1998)
- NH2-terminal globular domain of human platelet glycoprotein Ib alpha has a methionine 145/threonine145 amino acid polymorphism, which is associated with the HPA-2 (Ko) alloantigens. Kuijpers, R.W., Faber, N.M., Cuypers, H.T., Ouwehand, W.H., von dem Borne, A.E. J. Clin. Invest. (1992)
- Glycoprotein Ib polymorphisms influence platelet plug formation under high shear rates. Jilma-Stohlawetz, P., Homoncik, M., Jilma, B., Knechtelsdorfer, M., Unger, P., Mannhalter, C., Santoso, S., Panzer, S. Br. J. Haematol. (2003)
- Cloning and expression profiling of Hpa2, a novel mammalian heparanase family member. McKenzie, E., Tyson, K., Stamps, A., Smith, P., Turner, P., Barry, R., Hircock, M., Patel, S., Barry, E., Stubberfield, C., Terrett, J., Page, M. Biochem. Biophys. Res. Commun. (2000)
- Polymorphisms of platelet membrane glycoprotein Ib associated with arterial thrombotic disease. Gonzalez-Conejero, R., Lozano, M.L., Rivera, J., Corral, J., Iniesta, J.A., Moraleda, J.M., Vicente, V. Blood (1998)
- Determination of human platelet antigen frequencies in the Dutch population by immunophenotyping and DNA (allele-specific restriction enzyme) analysis. Simsek, S., Faber, N.M., Bleeker, P.M., Vlekke, A.B., Huiskes, E., Goldschmeding, R., von dem Borne, A.E. Blood (1993)
- The largest variant of platelet glycoprotein Ib alpha has four tandem repeats of 13 amino acids in the macroglycopeptide region and a genetic linkage with methionine145. Ishida, F., Furihata, K., Ishida, K., Yan, J., Kitano, K., Kiyosawa, K., Furuta, S. Blood (1995)
- Pumpkin hydroxypyruvate reductases with and without a putative C-terminal signal for targeting to microbodies may be produced by alternative splicing. Hayashi, M., Tsugeki, R., Kondo, M., Mori, H., Nishimura, M. Plant Mol. Biol. (1996)
- Role of five platelet membrane glycoprotein polymorphisms in branch retinal vein occlusion. Salomon, O., Moisseiev, J., Vilganski, T., Dardik, R., Kurtz, S., Shpringer, E., Steinberg, D.M., Rosenberg, N. Blood Coagul. Fibrinolysis (2006)
- A leaf-peroxisomal protein, hydroxypyruvate reductase, is produced by light-regulated alternative splicing. Mano, S., Hayashi, M., Nishimura, M. Cell Biochem. Biophys. (2000)
- von Willebrand factor but not alpha-thrombin binding to platelet glycoprotein Ibalpha is influenced by the HPA-2 polymorphism. Ulrichts, H., Vanhoorelbeke, K., Cauwenberghs, S., Vauterin, S., Kroll, H., Santoso, S., Deckmyn, H. Arterioscler. Thromb. Vasc. Biol. (2003)
- Platelet glycoprotein I(b)alpha and integrin alpha2 beta1 polymorphisms: gene frequencies and linkage disequilibrium in a population diversity panel. Di Paola, J., Jugessur, A., Goldman, T., Reiland, J., Tallman, D., Sayago, C., Murray, J.C. J. Thromb. Haemost. (2005)
- Polymorphisms of the human platelet antigens HPA-1, HPA-2, HPA-3, and HPA-5 on the platelet receptors for fibrinogen (GPIIb/IIIa), von Willebrand factor (GPIb/IX), and collagen (GPIa/IIa) are not correlated with an increased risk for stroke. Carlsson, L.E., Greinacher, A., Spitzer, C., Walther, R., Kessler, C. Stroke (1997)
- Genetic polymorphism in human platelet glycoprotein GP Ib/IX/V complex is enriched in GP V (CD42d). Koskela, S., Kekomäki, R., Partanen, J. Tissue Antigens (1998)
- Serum prolactin levels and their relationship to survival in women with operable breast cancer. Wang, D.Y., Stepniewska, K.A., Allen, D.S., Fentiman, I.S., Bulbrook, R.D., Kwa, H.G., De Stavola, B.L., Reed, M.J. Journal of clinical epidemiology. (1995)
- Gene polymorphism of platelet glycoprotein I balpha in Chinese patients with large- and small-artery subtypes of ischemic stroke. Gao, X.G., Huo, Y., Liu, X.Z., Teng, Z.P. Eur. Neurol. (2005)
- Gene frequencies of the HPA-1 and HPA-2 platelet antigen alleles among the Amerindians. Covas, D.T., Delgado, M., Zeitune, M.M., Guerreiro, J.F., Santos, S.E., Zago, M.A. Vox Sang. (1997)