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Gene Review

Ccpg1  -  cell cycle progression 1

Mus musculus

Synonyms: 1700030B06Rik, 1810073J13Rik, 9430028F23Rik, AI426686, AI875170, ...
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Disease relevance of Ccpg1

  • Cell cycle progression was blocked at temperatures below 27 degrees C. Immediately after shift to hypothermic temperatures, cells became more sensitive to hyperthermia [1].
  • Cell cycle progression of G2 fractions (75-80% G2 (4C) cells) from 8 h anaerobically cultured asynchronous hyperdiploid Ehrlich ascites tumor cells strain Karzel, separated by centrifugal elutriation, was studied after reaeration by flow cytometric methods, including the BrdU-H33258 technique and dual parameter measurements [2].

High impact information on Ccpg1


Biological context of Ccpg1


Anatomical context of Ccpg1


Associations of Ccpg1 with chemical compounds

  • Cell cycle progression was assessed by saponin/propidium iodide staining and fluorescence-activated cell sorter analysis [18].
  • Cell cycle progression was blocked in G(2)/M with 40 and 80 mcmol/L genistein [19].

Other interactions of Ccpg1


Analytical, diagnostic and therapeutic context of Ccpg1


  1. Cell killing and sensitization to heat shock by hypothermic incubation of asynchronous and synchronized mouse neuroblastoma cells. van Dongen, G., Zoutewelle, G., van Rijn, J., van Wijk, R. Cancer Res. (1985) [Pubmed]
  2. Growth kinetics of the G2-phase of Ehrlich ascites tumor cells, separated from anaerobically treated asynchronous cultures. Kroll, C., Kroll, W., Schneider, F. Z. Naturforsch., C, J. Biosci. (1987) [Pubmed]
  3. A DNA damage and stress inducible G protein-coupled receptor blocks cells in G2/M. Weng, Z., Fluckiger, A.C., Nisitani, S., Wahl, M.I., Le, L.Q., Hunter, C.A., Fernal, A.A., Le Beau, M.M., Witte, O.N. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  4. Cell cycle progression and apoptosis after irradiation in an acidic environment. Park, H.J., Lyons, J.C., Ohtsubo, T., Song, C.W. Cell Death Differ. (2000) [Pubmed]
  5. Regulation of cyclin G1 during murine hepatic regeneration following Dipin-induced DNA damage. Jensen, M.R., Factor, V.M., Thorgeirsson, S.S. Hepatology (1998) [Pubmed]
  6. Cip/Kip cyclin-dependent kinase inhibitors: brakes of the cell cycle engine during development. Nakayama, K., Nakayama, K. Bioessays (1998) [Pubmed]
  7. Antitumor activity of murine neutrophils demonstrated by cytometric analysis. Ackermann, M.F., Lamm, K.R., Wiegand, G.W., Luster, M.I. Cancer Res. (1989) [Pubmed]
  8. Effects of aclacinomycin on cell survival and cell cycle progression of cultured mammalian cells. Traganos, F., Staiano-Coico, L., Darzynkiewicz, Z., Melamed, M.R. Cancer Res. (1981) [Pubmed]
  9. Cell cycle progression of parthenogenetically activated mouse oocytes to interphase is dependent on the level of internal calcium. Vincent, C., Cheek, T.R., Johnson, M.H. J. Cell. Sci. (1992) [Pubmed]
  10. PTEN signaling pathways in melanoma. Wu, H., Goel, V., Haluska, F.G. Oncogene (2003) [Pubmed]
  11. Okadaic acid Co-induces vimentin expression and cell cycle arrest in MPC-11 mouse plasmacytoma cells. Giese, G., Wiegers, W., Kubbies, M., Scherbarth, A., Traub, P. J. Cell. Physiol. (1995) [Pubmed]
  12. Cell cycle progression kinetics of regenerating mouse epidermal cells: an in vivo study combining DNA flow cytometry, cell sorting, and [3H]dThd autoradiography. Clausen, O.P., Kirkhus, B., Schjølberg, A.R. J. Invest. Dermatol. (1986) [Pubmed]
  13. Cell-based delivery of cytokines allows for the differentiation of a doxycycline inducible oligodendrocyte precursor cell line in vitro. Muth, H., Elmshauser, C., Broad, S., Schipke, C., Kettenmann, H., Beck, E., Kann, M., Motta, I., Chen, U. The journal of gene medicine. (2001) [Pubmed]
  14. Proliferation of microglia, but not photoreceptors, in the outer nuclear layer of the rd-1 mouse. Zeiss, C.J., Johnson, E.A. Invest. Ophthalmol. Vis. Sci. (2004) [Pubmed]
  15. Intact follicular maturation and defective luteal function in mice deficient for cyclin- dependent kinase-4. Moons, D.S., Jirawatnotai, S., Tsutsui, T., Franks, R., Parlow, A.F., Hales, D.B., Gibori, G., Fazleabas, A.T., Kiyokawa, H. Endocrinology (2002) [Pubmed]
  16. Cell cycle progression of C3H 10T1/2 and 3T3 cells in the absence of an increase in c-myc RNA levels. Chang, J.D., Kennedy, A.R. Carcinogenesis (1988) [Pubmed]
  17. Cell cycle progression in denV-transfected murine fibroblasts exposed to ultraviolet radiation. Kusewitt, D.F., Budge, C.L., Nolla, H.A., Edwards, B.S., Ley, R.D. Mutat. Res. (1992) [Pubmed]
  18. Silibinin strongly synergizes human prostate carcinoma DU145 cells to doxorubicin-induced growth Inhibition, G2-M arrest, and apoptosis. Tyagi, A.K., Singh, R.P., Agarwal, C., Chan, D.C., Agarwal, R. Clin. Cancer Res. (2002) [Pubmed]
  19. Genistein inhibits growth of estrogen-independent human breast cancer cells in culture but not in athymic mice. Santell, R.C., Kieu, N., Helferich, W.G. J. Nutr. (2000) [Pubmed]
  20. The p53 tumor suppressor inhibits transcription of the TATA-less mouse DP1 promoter. Gopalkrishnan, R.V., Lam, E.W., Kedinger, C. J. Biol. Chem. (1998) [Pubmed]
  21. The cyclin kinase inhibitor p21WAF1, CIP1 is increased in experimental diabetic nephropathy: potential role in glomerular hypertrophy. Kuan, C.J., al-Douahji, M., Shankland, S.J. J. Am. Soc. Nephrol. (1998) [Pubmed]
  22. Deregulated c-Fos/AP-1 modulates expression of the cyclin and the cdk gene in splenic B cells stimulated with lipopolysaccharide. Phuchareon, J., Tokuhisa, T. Cancer Lett. (1995) [Pubmed]
  23. Interferon-gamma impairs physiologic downregulation of cyclin-dependent kinase inhibitor, p27Kip1, during G1 phase progression in macrophages. Matsuoka, M., Nishimoto, I., Asano, S. Exp. Hematol. (1999) [Pubmed]
  24. Cell cycle progression without cyclin E/CDK2: breaking down the walls of dogma. Gladden, A.B., Diehl, J.A. Cancer Cell (2003) [Pubmed]
  25. Effects of prospidine on survival and growth of mammalian cells in culture. Traganos, F., Staiano-Coico, L., Darzynkiewicz, Z., Melamed, M.R. J. Natl. Cancer Inst. (1980) [Pubmed]
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