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Gene Review

CCPG1  -  cell cycle progression 1

Homo sapiens

Synonyms: CCP8, CPR8, Cell cycle progression protein 1, Cell cycle progression restoration protein 8, KIAA1254
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Disease relevance of CCPG1


Psychiatry related information on CCPG1


High impact information on CCPG1


Biological context of CCPG1


Anatomical context of CCPG1


Associations of CCPG1 with chemical compounds


Physical interactions of CCPG1


Regulatory relationships of CCPG1


Other interactions of CCPG1


Analytical, diagnostic and therapeutic context of CCPG1


  1. DnaA couples DNA replication and the expression of two cell cycle master regulators. Collier, J., Murray, S.R., Shapiro, L. EMBO J. (2006) [Pubmed]
  2. Cell cycle progression of B-chronic lymphocytic leukemia cells induced to differentiate by TPA. Carlsson, M., Tötterman, T.H., Matsson, P., Nilsson, K. Blood (1988) [Pubmed]
  3. Cell-cycle progression and apoptosis in K562 and Molt-4 cells after cell-to-cell transmission of HTLV-I: modulation by interferons. D'Onofrio, C., Puglianiello, A., Lanzilli, G., Peci, E., Starace, G., Bonmassar, E. Cell Death Differ. (1995) [Pubmed]
  4. Human cytomegalovirus infection inhibits G1/S transition. Dittmer, D., Mocarski, E.S. J. Virol. (1997) [Pubmed]
  5. Translocation of cdk2 to the nucleus during G1-phase in PDGF-stimulated human fibroblasts. Dietrich, C., Wallenfang, K., Oesch, F., Wieser, R. Exp. Cell Res. (1997) [Pubmed]
  6. Cell cycle progression towards Alzheimer's disease. Copani, A., Condorelli, F., Canonico, P.L., Nicoletti, F., Sortino, M.A. Funct. Neurol. (2001) [Pubmed]
  7. Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F. Brennan, P., Babbage, J.W., Burgering, B.M., Groner, B., Reif, K., Cantrell, D.A. Immunity (1997) [Pubmed]
  8. 5-ASA affects cell cycle progression in colorectal cells by reversibly activating a replication checkpoint. Luciani, M.G., Campregher, C., Fortune, J.M., Kunkel, T.A., Gasche, C. Gastroenterology (2007) [Pubmed]
  9. Cell cycle progression and de novo centriole assembly after centrosomal removal in untransformed human cells. Uetake, Y., Loncarek, J., Nordberg, J.J., English, C.N., La Terra, S., Khodjakov, A., Sluder, G. J. Cell Biol. (2007) [Pubmed]
  10. Regulation of the ubiquitin-conjugating enzyme hHR6A by CDK-mediated phosphorylation. Sarcevic, B., Mawson, A., Baker, R.T., Sutherland, R.L. EMBO J. (2002) [Pubmed]
  11. Activity of the APC(Cdh1) form of the anaphase-promoting complex persists until S phase and prevents the premature expression of Cdc20p. Huang, J.N., Park, I., Ellingson, E., Littlepage, L.E., Pellman, D. J. Cell Biol. (2001) [Pubmed]
  12. MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity. Li, Y., Gorbea, C., Mahaffey, D., Rechsteiner, M., Benezra, R. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
  13. RNA Interference-Mediated Silencing of Mitotic Kinesin KIF14 Disrupts Cell Cycle Progression and Induces Cytokinesis Failure. Carleton, M., Mao, M., Biery, M., Warrener, P., Kim, S., Buser, C., Marshall, C.G., Fernandes, C., Annis, J., Linsley, P.S. Mol. Cell. Biol. (2006) [Pubmed]
  14. Cell cycle progression and chromosome segregation in mammalian cells cultured in the presence of the topoisomerase II inhibitors ICRF-187 [(+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane; ADR-529] and ICRF-159 (Razoxane). Gorbsky, G.J. Cancer Res. (1994) [Pubmed]
  15. Cell cycle progression proteins (cyclins), oncogene expression, and signal transduction during the proliferative response of human hepatocytes to hepatocyte growth factor. Gómez-Lechón, M.J., Guillén, I., Ponsoda, X., Fabra, R., Trullenque, R., Nakamura, T., Castell, J.V. Hepatology (1996) [Pubmed]
  16. Spatial complexity of mechanisms controlling a bacterial cell cycle. Viollier, P.H., Shapiro, L. Curr. Opin. Microbiol. (2004) [Pubmed]
  17. A NIMA-related protein kinase is essential for completion of the sexual cycle of malaria parasites. Reininger, L., Billker, O., Tewari, R., Mukhopadhyay, A., Fennell, C., Dorin-Semblat, D., Doerig, C., Goldring, D., Harmse, L., Ranford-Cartwright, L., Packer, J., Doerig, C. J. Biol. Chem. (2005) [Pubmed]
  18. Estradiol and EGF requirements for cell-cycle progression of normal human mammary epithelial cells in culture. Colomb, E., Berthon, P., Dussert, C., Calvo, F., Martin, P.M. Int. J. Cancer (1991) [Pubmed]
  19. Increased expression of cyclin E is associated with an increased resistance to doxorubicin in rat fibroblasts. Sgambato, A., Camerini, A., Pani, G., Cangiano, R., Faraglia, B., Bianchino, G., De Bari, B., Galeotti, T., Cittadini, A. Br. J. Cancer (2003) [Pubmed]
  20. Cell-cycle progression during continuous low dose rate irradiation of a human bladder carcinoma cell line. Skladowski, K., McMillan, T.J., Peacock, J., Titley, J., Steel, G.G. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. (1993) [Pubmed]
  21. Arrest of cell cycle progression of HeLa cells in the early G1 phase in K(+)-depleted conditions and its recovery upon addition of insulin and LDL. Yamaguchi, H., Hosokawa, K., Jiang, Z.L., Takahashi, A., Ikehara, T., Miyamoto, H. J. Cell. Biochem. (1993) [Pubmed]
  22. Oocyte activation and passage through the metaphase/anaphase transition of the meiotic cell cycle is blocked in clams by inhibitors of HMG-CoA reductase activity. Turner, J.E., Minkoff, C.G., Martin, K.H., Misra, R., Swenson, K.I. J. Cell Biol. (1995) [Pubmed]
  23. Contribution of aldose reductase to diabetic hyperproliferation of vascular smooth muscle cells. Srivastava, S., Ramana, K.V., Tammali, R., Srivastava, S.K., Bhatnagar, A. Diabetes (2006) [Pubmed]
  24. Cell cycle progression of glutathione-depleted human peripheral blood mononuclear cells is inhibited at S phase. Messina, J.P., Lawrence, D.A. J. Immunol. (1989) [Pubmed]
  25. Interference with 3',5'-Cyclic Adenosine Monophosphate Response Element Binding Protein Stimulates Apoptosis through Aberrant Cell Cycle Progression and Checkpoint Activation. Dworet, J.H., Meinkoth, J.L. Mol. Endocrinol. (2006) [Pubmed]
  26. Integrins and cell proliferation: regulation of cyclin-dependent kinases via cytoplasmic signaling pathways. Schwartz, M.A., Assoian, R.K. J. Cell. Sci. (2001) [Pubmed]
  27. Structure of yellow lupine genes coding for mitotic cyclins. Jeleńska, J., Zaborowska, Z., Legocki, A.B. Acta Biochim. Pol. (1999) [Pubmed]
  28. Role for cyclin A-dependent kinase in DNA replication in human S phase cell extracts. Fotedar, A., Cannella, D., Fitzgerald, P., Rousselle, T., Gupta, S., Dorée, M., Fotedar, R. J. Biol. Chem. (1996) [Pubmed]
  29. Novel form of p21(WAF1/CIP1/SDI1) protein in phorbol ester-induced G2/M arrest. Tchou, W.W., Rom, W.N., Tchou-Wong, K.M. J. Biol. Chem. (1996) [Pubmed]
  30. Antisense phosphorothioate oligonucleotides specifically down-regulate cdc25B causing S-phase delay and persistent antiproliferative effects. Garner-Hamrick, P.A., Fisher, C. Int. J. Cancer (1998) [Pubmed]
  31. Cyclin-dependent kinase inhibitor p27KIP1 in lymphoid tissue: p27KIP1 expression is inversely proportional to the proliferative index. Sánchez-Beato, M., Sáez, A.I., Martínez-Montero, J.C., Sol Mateo, M., Sánchez-Verde, L., Villuendas, R., Troncone, G., Piris, M.A. Am. J. Pathol. (1997) [Pubmed]
  32. Overexpression of CDC25A and CDC25B in head and neck cancers. Gasparotto, D., Maestro, R., Piccinin, S., Vukosavljevic, T., Barzan, L., Sulfaro, S., Boiocchi, M. Cancer Res. (1997) [Pubmed]
  33. Cell-cycle progression is not essential for c-Myc to block differentiation. Ryan, K.M., Birnie, G.D. Oncogene (1997) [Pubmed]
  34. Induction of apoptosis by flavopiridol unrelated to cell cycle arrest in germ cell tumour derived cell lines. Mayer, F., Mueller, S., Malenke, E., Kuczyk, M., Hartmann, J.T., Bokemeyer, C. Investigational new drugs. (2005) [Pubmed]
  35. Molecular events associated with reactive oxygen species and cell cycle progression in mammalian cells. Boonstra, J., Post, J.A. Gene (2004) [Pubmed]
  36. Enhanced S phase delay and inhibition of replication of an undamaged shuttle vector in UVC-irradiated xeroderma pigmentosum variant. Bullock, S.K., Kaufmann, W.K., Cordeiro-Stone, M. Carcinogenesis (2001) [Pubmed]
  37. Effect of beta-carotene on cell cycle progression of human fibroblasts. Stivala, L.A., Savio, M., Cazzalini, O., Pizzala, R., Rehak, L., Bianchi, L., Vannini, V., Prosperi, E. Carcinogenesis (1996) [Pubmed]
  38. Rapamycin inhibits hTERT telomerase mRNA expression, independent of cell cycle arrest. Bae-Jump, V.L., Zhou, C., Gehrig, P.A., Whang, Y.E., Boggess, J.F. Gynecol. Oncol. (2006) [Pubmed]
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