Gene Review:
GAL80 - Gal80p
Saccharomyces cerevisiae S288c
Synonyms:
Galactose/lactose metabolism regulatory protein GAL80, YM9827.01, YM9958.12, YML051W
- Mutational hypersensitivity of a gene regulatory protein: Saccharomyces cerevisiae Gal80p. Melcher, K. Genetics (2005)
- Peptides selected to bind the Gal80 repressor are potent transcriptional activation domains in yeast. Han, Y., Kodadek, T. J. Biol. Chem. (2000)
- Dual feedback loops in the GAL regulon suppress cellular heterogeneity in yeast. Ramsey, S.A., Smith, J.J., Orrell, D., Marelli, M., Petersen, T.W., de Atauri, P., Bolouri, H., Aitchison, J.D. Nat. Genet. (2006)
- Elevated recombination rates in transcriptionally active DNA. Thomas, B.J., Rothstein, R. Cell (1989)
- Interaction of positive and negative regulatory proteins in the galactose regulon of yeast. Johnston, S.A., Salmeron, J.M., Dincher, S.S. Cell (1987)
- The carboxy-terminal 30 amino acids of GAL4 are recognized by GAL80. Ma, J., Ptashne, M. Cell (1987)
- Cell signaling can direct either binary or graded transcriptional responses. Biggar, S.R., Crabtree, G.R. EMBO J. (2001)
- Overproduction of the GAL1 or GAL3 protein causes galactose-independent activation of the GAL4 protein: evidence for a new model of induction for the yeast GAL/MEL regulon. Bhat, P.J., Hopper, J.E. Mol. Cell. Biol. (1992)
- Expression of the Saccharomyces cerevisiae GAL7 gene on autonomous plasmids. Baker, S.M., Okkema, P.G., Jaehning, J.A. Mol. Cell. Biol. (1984)
- Autogenous regulation of the Saccharomyces cerevisiae regulatory gene GAL80. Igarashi, M., Segawa, T., Nogi, Y., Suzuki, Y., Fukasawa, T. Mol. Gen. Genet. (1987)
- Sites for interaction between Gal80p and Gal1p in Kluyveromyces lactis: structural model of galactokinase based on homology to the GHMP protein family. Menezes, R.A., Amuel, C., Engels, R., Gengenbacher, U., Labahn, J., Hollenberg, C.P. J. Mol. Biol. (2003)
- Quantitative analysis of GAL genetic switch of Saccharomyces cerevisiae reveals that nucleocytoplasmic shuttling of Gal80p results in a highly sensitive response to galactose. Verma, M., Bhat, P.J., Venkatesh, K.V. J. Biol. Chem. (2003)
- Functional domains of the yeast regulatory protein GAL4. Johnston, S.A., Zavortink, M.J., Debouck, C., Hopper, J.E. Proc. Natl. Acad. Sci. U.S.A. (1986)
- Gal80 proteins of Kluyveromyces lactis and Saccharomyces cerevisiae are highly conserved but contribute differently to glucose repression of the galactose regulon. Zenke, F.T., Zachariae, W., Lunkes, A., Breunig, K.D. Mol. Cell. Biol. (1993)
- Purification and characterization of the yeast negative regulatory protein GAL80. Yun, S.J., Hiraoka, Y., Nishizawa, M., Takio, K., Titani, K., Nogi, Y., Fukasawa, T. J. Biol. Chem. (1991)
- Regulation of expression of the galactose gene cluster in Saccharomyces cerevisiae. II. The isolation and dosage effect of the regulatory gene GAL80. Nogi, Y., Shimada, H., Matsuzaki, Y., Hashimoto, H., Fukasawa, T. Mol. Gen. Genet. (1984)
- The Gal3p-Gal80p-Gal4p transcription switch of yeast: Gal3p destabilizes the Gal80p-Gal4p complex in response to galactose and ATP. Sil, A.K., Alam, S., Xin, P., Ma, L., Morgan, M., Lebo, C.M., Woods, M.P., Hopper, J.E. Mol. Cell. Biol. (1999)
- Control of yeast GAL genes by MIG1 repressor: a transcriptional cascade in the glucose response. Nehlin, J.O., Carlberg, M., Ronne, H. EMBO J. (1991)
- Gal3p and Gal1p interact with the transcriptional repressor Gal80p to form a complex of 1:1 stoichiometry. Timson, D.J., Ross, H.C., Reece, R.J. Biochem. J. (2002)
- A transcriptional activating region with two contrasting modes of protein interaction. Ansari, A.Z., Reece, R.J., Ptashne, M. Proc. Natl. Acad. Sci. U.S.A. (1998)
- A RNA polymerase III-based two-hybrid system to study RNA polymerase II transcriptional regulators. Marsolier, M.C., Prioleau, M.N., Sentenac, A. J. Mol. Biol. (1997)
- Molecular characterization of MRG19 of Saccharomyces cerevisiae. Implication in the regulation of galactose and nonfermentable carbon source utilization. Khanday, F.A., Saha, M., Bhat, P.J. Eur. J. Biochem. (2002)
- A GAL10-CYC1 hybrid yeast promoter identifies the GAL4 regulatory region as an upstream site. Guarente, L., Yocum, R.R., Gifford, P. Proc. Natl. Acad. Sci. U.S.A. (1982)
- Controlled transcription of the yeast regulatory gene GAL80. Shimada, H., Fukasawa, T. Gene (1985)
- Multiple copies of MRG19 suppress transcription of the GAL1 promoter in a GAL80-dependent manner in Saccharomyces cerevisiae. Kabir, M.A., Khanday, F.A., Mehta, D.V., Bhat, P.J. Mol. Gen. Genet. (2000)
- Purification and characterization of the yeast transcriptional activator GAL4. Parthun, M.R., Jaehning, J.A. J. Biol. Chem. (1990)
- Replacement of a conserved tyrosine by tryptophan in Gal3p of Saccharomyces cerevisiae reduces constitutive activity: implications for signal transduction in the GAL regulon. Lakshminarasimhan, A., Bhat, P.J. Mol. Genet. Genomics (2005)
- Interaction between transcriptional activator protein LAC9 and negative regulatory protein GAL80. Salmeron, J.M., Langdon, S.D., Johnston, S.A. Mol. Cell. Biol. (1989)
- Reconstitution of mRNA editing in yeast using a Gal4-apoB-Gal80 fusion transcript as the selectable marker. Lellek, H., Welker, S., Diehl, I., Kirsten, R., Greeve, J. J. Biol. Chem. (2002)
- Molecular cloning of the GAL80 gene from Saccharomyces cerevisiae and characterization of a gal80 deletion. Yocum, R.R., Johnston, M. Gene (1984)