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Gene Review

FGFBP1  -  fibroblast growth factor binding protein 1

Homo sapiens

Synonyms: 17 kDa HBGF-binding protein, 17 kDa heparin-binding growth factor-binding protein, FGF-BP, FGF-BP1, FGF-binding protein 1, ...
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Disease relevance of FGFBP1


High impact information on FGFBP1


Biological context of FGFBP1


Anatomical context of FGFBP1


Associations of FGFBP1 with chemical compounds


Regulatory relationships of FGFBP1


Other interactions of FGFBP1


  1. Induction of the angiogenic modulator fibroblast growth factor-binding protein by epidermal growth factor is mediated through both MEK/ERK and p38 signal transduction pathways. Harris, V.K., Coticchia, C.M., Kagan, B.L., Ahmad, S., Wellstein, A., Riegel, A.T. J. Biol. Chem. (2000) [Pubmed]
  2. Mitogen-induced expression of the fibroblast growth factor-binding protein is transcriptionally repressed through a non-canonical E-box element. Harris, V.K., Coticchia, C.M., List, H.J., Wellstein, A., Riegel, A.T. J. Biol. Chem. (2000) [Pubmed]
  3. The human papillomavirus (HPV) 16 E6 oncoprotein leads to an increase in gene expression of the angiogenic switch molecule FGF-BP in non-immortalized human keratinocytes. Stöppler, H., Malerczyk, C., Block, K., Aigner, A., Czubayko, F. Oncogene (2001) [Pubmed]
  4. Fibroblast growth factor-binding protein expression changes with disease progression in clinical and experimental human squamous epithelium. Sauter, E.R., Nesbit, M., Tichansky, D., Liu, Z.J., Shirakawa, T., Palazzo, J., Herlyn, M. Int. J. Cancer (2001) [Pubmed]
  5. Complex regulation of the fibroblast growth factor-binding protein in MDA- MB-468 breast cancer cells by CCAAT/enhancer-binding protein beta. Kagan, B.L., Henke, R.T., Cabal-Manzano, R., Stoica, G.E., Nguyen, Q., Wellstein, A., Riegel, A.T. Cancer Res. (2003) [Pubmed]
  6. Expression of a fibroblast growth factor-binding protein during the development of adenocarcinoma of the pancreas and colon. Tassi, E., Henke, R.T., Bowden, E.T., Swift, M.R., Kodack, D.P., Kuo, A.H., Maitra, A., Wellstein, A. Cancer Res. (2006) [Pubmed]
  7. Enhancement of fibroblast growth factor (FGF) activity by an FGF-binding protein. Tassi, E., Al-Attar, A., Aigner, A., Swift, M.R., McDonnell, K., Karavanov, A., Wellstein, A. J. Biol. Chem. (2001) [Pubmed]
  8. Immunohistochemical expression of heparin-binding protein 17/fibroblast growth factor-binding protein-1 (HBp17/FGFBP-1) as an angiogenic factor in head and neck tumorigenesis. Begum, S., Zhang, Y., Shintani, T., Toratani, S., Sato, J.D., Okamoto, T. Oncol. Rep. (2007) [Pubmed]
  9. Mechanism of fibroblast growth factor-binding protein 1 repression by TGF-beta. Briones, V.R., Chen, S., Riegel, A.T., Lechleider, R.J. Biochem. Biophys. Res. Commun. (2006) [Pubmed]
  10. Differential regulation of a fibroblast growth factor-binding protein by receptor-selective analogs of retinoic acid. Boyle, B.J., Harris, V.K., Liaudet-Coopman, E.D., Riegel, A.T., Wellstein, A. Biochem. Pharmacol. (2000) [Pubmed]
  11. Serum induction of the fibroblast growth factor-binding protein (FGF-BP) is mediated through ERK and p38 MAP kinase activation and C/EBP-regulated transcription. Harris, V.K., Kagan, B.L., Ray, R., Coticchia, C.M., Liaudet-Coopman, E.D., Wellstein, A., Tate Riegel, A. Oncogene (2001) [Pubmed]
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