Disease relevance of Retinal Hemorrhage

• Retinal hemorrhage in retinopathy of prematurity associated with tocopherol treatment [1].
• Patchy ischemic retinal whitening has a perivenular distribution in the macula, has no fluorescein angiographic correlate in milder cases, can occur before any retinal hemorrhages or macular edema, and resolves in 2 to 4 weeks [2].
• Although retinal hemorrhages are known to occur in patients with CF, we speculate that the retinopathy in this case was partially related to altitudinal change and that patients with chronic hypoxemia may be predisposed to high-altitude retinopathy at much lower altitudes [3].
• OBJECTIVES: To determine the prevalence of unusual cataracts in a population of workers in the United States exposed to organic nitrate explosives, to determine whether associations exist with reported cataract risk factors, and to determine if other eye effects (eg, retinal hemorrhage) are associated with exposure [4].
• Rearing neonatal rats in hyperoxia induces the development of retinal hemorrhages and retinal dysplasia [5].

High impact information on Retinal Hemorrhage

• Retinal hemorrhages in subacute carbon monoxide poisoning. Exposures in homes with blocked furnace flues [6].
• However, retinal hemorrhage occurred in six patients (24%) during IFN-alpha therapy [7].
• Among all 232 infants examined, those treated with tocopherol had more retinal hemorrhage than placebo-treated infants (8/121 placebo treated v 16/111 tocopherol treated), and retinal hemorrhage correlated positively (P less than .01) with plasma levels of tocopherol after the first 2 weeks of age [8].
• RESULTS: Dogs fed a 30% galactose diet for 28 to 41 months were observed by fluorescein angiography and color fundus photography to develop, in order of frequency, microaneurysms, retinal hemorrhages, intraretinal microvascular abnormalities, retinal nonperfused areas, and varicose and serpiginous veins [9].
• Retinal hemorrhage as a consequence of epidural steroid injection [10].

Chemical compound and disease context of Retinal Hemorrhage

• The development of retinal hemorrhages correlated strongly with plasma tocopherol levels from three weeks to three months (P less than 0.05) [1].
• The vascular dilation caused by adenosine, dipyridamole, and particularly NECA, but not nitroprusside or dibutyryl cyclic adenosine monophosphate, was accompanied by retinal hemorrhages, producing a picture reminiscent of some features of ischemic retinopathies [11].
• Retinal hemorrhage caused by overdose of methaqualone (Quaalude) [12].
• We used a red-light krypton laser (647 nm) because the light is not absorbed by the hemoglobin in the retinal hemorrhage or by the macular luteal pigment (xanthophyll), and because it is transmitted into the choroid, allowing treatment within the macular zone with less damage to the internal retinal elements [13].
• 3. Retinal findings include cloudy vitreous, preretinal and subretinal exudate, and retinal hemorrhages [14].

Biological context of Retinal Hemorrhage

• After 4.75 +/- 0.7 months, BCVA significantly improved, intraocular pressure was well controlled, and fluorescein angiography showed perfused state and reduction of the number of retinal hemorrhages in all eyes [15].

Anatomical context of Retinal Hemorrhage

• In the 48-year-old patient, who had late-stage FAP, examination of the fundus revealed pinpoint white amyloid opacities over the retinal surface, sheathing of retinal vessels, and scattered retinal hemorrhages [16].

Gene context of Retinal Hemorrhage

• A 4-year-old Black child was admitted to hospital in coma and with retinal hemorrhages [17].
• CONCLUSION: Large dome-shaped retinal hemorrhages with Terson syndrome can be located beneath the internal limiting membrane of the retina [18].
• Of two patients with type 5 hyperlipoproteinemia, one exhibited lipemia retinalis with multiple retinal hemorrhages and intraretinal lipid extravasations [19].
• However, retinal hemorrhages or cotton-wool spots typical of SLE were not observed in their courses [20].

Analytical, diagnostic and therapeutic context of Retinal Hemorrhage

• PURPOSE: To present a case of a unilateral diffuse retinal hemorrhage in a 15-year-old girl, who underwent bilateral trabeculectomy for steroid induced glaucoma [21].
• A low initial Glasgow Coma Scale score, severe retinal hemorrhages, presence of skull fracture, and cranial growth deceleration were significantly associated with poor developmental outcome [22].

References