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Disease relevance of Photoplethysmography


High impact information on Photoplethysmography

  • METHODS: Twenty sexually functional women participated in 2 experimental conditions in which subjective (self-report) and physiological (vaginal photoplethysmography) sexual responses to erotic stimuli were measured following administration of either ephedrine sulfate (50 mg) or placebo in a randomized, double-blind, cross-over protocol [4].
  • Similarly, a pharmacodynamic model was applied to the 7360 effect measurements, i.e. the decrease of peak blood pressure response to intravenous angiotensin challenge recorded by finger photoplethysmography [5].
  • After six weeks on diet the vasodilator responses to acetylcholine and glyceryl trinitrate were measured by photoplethysmography of the rabbit ear [6].
  • Noninvasive assessment of local nicotinate pharmacodynamics by photoplethysmography [7].
  • Indirect systolic blood pressure was measured by photoplethysmography in unanesthetized mice fed either a basal or high salt diet, and found to be significantly higher in iNOS-deficient mice than in wild type controls at three months of age (P=0.038 (basal diet) and P=0.0005 (high salt diet)) [8].

Biological context of Photoplethysmography


Associations of Photoplethysmography with chemical compounds

  • Since none of these quantifies intestinal blood flow, we measured flow at the detection thresholds of Doppler ultrasound, photoplethysmography, and intravenously administered fluorescein, perfused the intestines at these threshold levels, and assessed histologic evidence of ischemic damage [12].
  • In 20 patients scheduled for extracorporeal shock wave lithotripsy (ESWL), the onset of sympathetic blockade after epidural anaesthesia (catheter insertion at the presumed level L2-L3, and injection of 20 ml prilocaine 2% with epinephrine 5 micrograms/ml) was objectively evaluated by photoplethysmography [13].
  • Photoplethysmography proved to be a very efficient and inexpensive method of studying the effects of pentoxifylline [14].
  • Transmitted-light photoplethysmography (TLP) was applied to teeth in situ using a tungsten light, or one of two light-emitting diodes (LED) with peak wavelengths of 565 and 695 nm [15].
  • In a randomized, placebo-controlled, crossover study, 15 ambulatory patients with Raynaud's phenomenon, treated for three weeks with ketanserin 80 mg/day and pentoxiphylline 1,200 mg/day, were evaluated by subjective symptom scores, daily frequency and duration of attacks, and photoplethysmography, at room temperature and after cold test [16].

Gene context of Photoplethysmography


Analytical, diagnostic and therapeutic context of Photoplethysmography


  1. The use of infrared photoplethysmography in identifying early intestinal ischemia. Pearce, W.H., Jones, D.N., Warren, G.H., Bartle, E.J., Whitehill, T.A., Rutherford, R.B. Archives of surgery (Chicago, Ill. : 1960) (1987) [Pubmed]
  2. Noninvasive beat-to-beat arterial blood pressure measurement during VVI and DDD pacing: relationship to symptomatic benefit from DDD pacing. Channon, K.M., Hargreaves, M.R., Gardner, M., Ormerod, O.J. Pacing and clinical electrophysiology : PACE. (1997) [Pubmed]
  3. Upper extremities deep venous thrombosis: comparison of light reflection rheography and colour duplex ultrasonography for diagnosis and follow-up. Petrakis, I.E., Sciacca, V., Katsamouris, A.N. Panminerva medica. (2001) [Pubmed]
  4. Ephedrine-activated physiological sexual arousal in women. Meston, C.M., Heiman, J.R. Arch. Gen. Psychiatry (1998) [Pubmed]
  5. Population pharmacokinetic-pharmacodynamic modelling of angiotensin receptor blockade in healthy volunteers. Csajka, C., Buclin, T., Fattinger, K., Brunner, H.R., Biollaz, J. Clinical pharmacokinetics. (2002) [Pubmed]
  6. Vitamin E restores endothelium dependent vasodilatation in cholesterol fed rabbits: in vivo measurements by photoplethysmography. Klemsdal, T.O., Andersson, T.L., Matz, J., Ferns, G.A., Gjesdal, K., Anggård, E.E. Cardiovasc. Res. (1994) [Pubmed]
  7. Noninvasive assessment of local nicotinate pharmacodynamics by photoplethysmography. Tur, E., Guy, R.H., Tur, M., Maibach, H.I. J. Invest. Dermatol. (1983) [Pubmed]
  8. Mice lacking inducible nitric oxide synthase develop spontaneous hypercholesterolaemia and aortic atheromas. Ihrig, M., Dangler, C.A., Fox, J.G. Atherosclerosis (2001) [Pubmed]
  9. Spatial variability of vasodilatation in human forearm skin. Tur, E., Maibach, H.I., Guy, R.H. Br. J. Dermatol. (1985) [Pubmed]
  10. EEG spectral entropy, heart rate, photoplethysmography and motor responses to skin incision during sevoflurane anaesthesia. Seitsonen, E.R., Korhonen, I.K., van Gils, M.J., Huiku, M., Lötjönen, J.M., Korttila, K.T., Yli-Hankala, A.M. Acta anaesthesiologica Scandinavica. (2005) [Pubmed]
  11. Functional vascular disorders: treatment with pentoxifylline. Neirotti, M., Longo, F., Molaschi, M., Macchione, C., Pernigotti, L. Angiology. (1987) [Pubmed]
  12. Detection thresholds of nonocclusive intestinal hypoperfusion by Doppler ultrasound, photoplethysmography, and fluorescein. Whitehill, T.A., Pearce, W.H., Rosales, C., Yano, T., Van Way, C.W., Rutherford, R.B. J. Vasc. Surg. (1988) [Pubmed]
  13. Asymmetric onset of sympathetic blockade in epidural anaesthesia shows no relation to epidural catheter position. Gielen, M.J., Slappendel, R., Merx, J.L. Acta anaesthesiologica Scandinavica. (1991) [Pubmed]
  14. Photoplethysmographic documentation of improved microcirculation after pentoxifylline therapy. Roeren, T., LeVeen, R.F., Nugent, L. Angiology. (1988) [Pubmed]
  15. Optical characteristics of human extracted teeth and the possible application of photoplethysmography to the human pulp. Ikawa, M., Horiuchi, H., Ikawa, K. Arch. Oral Biol. (1994) [Pubmed]
  16. Comparative efficacy of ketanserin and pentoxiphylline in treatment of Raynaud's phenomenon. Arosio, E., Montesi, G., Zannoni, M., Paluani, F., Lechi, A. Angiology. (1989) [Pubmed]
  17. Value of toe pulse waves in addition to systolic pressures in the assessment of the severity of peripheral arterial disease and critical limb ischemia. Carter, S.A., Tate, R.B. J. Vasc. Surg. (1996) [Pubmed]
  18. Assessment of stripping the long saphenous vein in the treatment of primary varicose veins. Sarin, S., Scurr, J.H., Coleridge Smith, P.D. The British journal of surgery. (1992) [Pubmed]
  19. Potential application of photoplethysmography technique in evaluating microcirculatory status of STAMP patients: preliminary report. Lee, T.Q., Barnett, S.L., Shanfield, S.L., Anzel, S.H. Journal of rehabilitation research and development. (1990) [Pubmed]
  20. Prevalence of Raynaud's phenomenon in patients with idiopathic carpal tunnel syndrome. Chung, M.S., Gong, H.S., Baek, G.H. The Journal of bone and joint surgery. British volume. (1999) [Pubmed]
  21. Photoplethysmography. Part 2. Influence of light source wavelength. Lindberg, L.G., Oberg, P.A. Medical & biological engineering & computing. (1991) [Pubmed]
  22. Syncope during exercise, documented with continuous blood pressure monitoring during ergometer testing. Krediet, C.T., Wilde, A.A., Halliwill, J.R., Wieling, W. Clin. Auton. Res. (2005) [Pubmed]
  23. Epinephrine-supplemented local anesthetics for ear and nose surgery: clinical use without complications in more than 10,000 surgical procedures. Häfner, H.M., Röcken, M., Breuninger, H. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. (2005) [Pubmed]
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