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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
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Disease relevance of Ultrasonics


Psychiatry related information on Ultrasonics


High impact information on Ultrasonics

  • When awake goats were subjected to isobaric gas switching from saturation (17 hours) on 4.7 atmospheres of nitrogen (0.3 atmosphere of oxygen) to 4.7 atmospheres of helium (0.3 atmosphere of oxygen), bubbles detected by 5-megahertz Doppler ultrasound in the posterior vena cava 20 to 60 minutes after the switch continued for 4 hours [8].
  • METHODS AND RESULTS: Using simultaneous intravascular two-dimensional and Doppler ultrasound, we examined the effect of intracoronary testosterone in coronary conductance and resistance arteries in 10 anesthetized dogs (5 male, 5 female) [9].
  • Effect of selective angiotensin II receptor antagonism and angiotensin converting enzyme inhibition on the coronary vasculature in vivo. Intravascular two-dimensional and Doppler ultrasound studies [10].
  • These hemodynamic alterations, measured by MRI and Doppler ultrasound, were used in this study for the molecular imaging of Met activity in vivo [11].
  • Tumor-bearing BALB/C mice were i.v. injected with HGF/SF and imaged using magnetic resonance imaging (MRI) and Doppler ultrasound [11].

Chemical compound and disease context of Ultrasonics


Biological context of Ultrasonics


Anatomical context of Ultrasonics

  • This study examined vasomotor responses to incremental blood flow induced by papaverine in the epicardial arteries of 10 patients with angiographically normal coronary arteries (group 1) and in 14 patients with arterial irregularities (group 2) using quantitative angiography and Doppler ultrasound flow velocity measurements [22].
  • METHODS: The effects of systemic intravenous adrenomedullin (3.2-16.0 pmol/[kg. min])) on choroidal blood flow were assessed by measurement of fundus pulsation amplitude and laser Doppler flow in the macula, and on blood flow in the ophthalmic artery by ultrasound Doppler flow in pilot studies (n = 7) [23].
  • 1. Beat-by-beat changes in cardiac performance in response to arterial baroreceptor stimulation induced by phenylephrine were evaluated by pulsed-wave aortic Doppler ultrasound in eighteen subjects [24].
  • Serial computed tomography with measurement of midline and septum pellucidum shift and data on the presence and location of vascular occlusion by angiography or Doppler ultrasound were obtained directly after admission [25].
  • 1. Superior mesenteric artery blood flow was examined by Doppler ultrasound in six male subjects aged 19-23 years during the infusion of saline (control), 10 and 40 ng of adrenaline min-1kg-1 for 30 min, or propranolol and 10 ng of adrenaline min-1kg-1 for 30 min, on four separate occasions [26].

Associations of Ultrasonics with chemical compounds

  • Assessment of coronary conductance and resistance vessel reactivity in response to nitroglycerin, ergonovine and adenosine: in vivo studies with simultaneous intravascular two-dimensional and Doppler ultrasound [27].
  • To evaluate its clinical usefulness, the recently introduced breath-holding maneuver as a carbon dioxide-dependent vasodilatory stimulus was compared with the acetazolamide challenge by means of transcranial Doppler ultrasound and stable xenon-enhanced computed tomography [28].
  • We compared the systemic and regional hemodynamic effects of nifedipine and lisinopril in 26 elderly hypertensive patients with the use of the pulsed Doppler ultrasound technique [29].
  • We have used it to examine the relations between the metabolites in the infarct (N-acetylaspartate [NAA] and lactate) and the time lapse from stroke to MRS, the presenting neurological deficit, infarct size and swelling (on MRI), blood flow to the infarct (estimated by transcranial Doppler ultrasound), and clinical outcome [30].
  • Color Doppler ultrasound measurements after topical and retrobulbar epinephrine in primate eyes [31].

Gene context of Ultrasonics


Analytical, diagnostic and therapeutic context of Ultrasonics


  1. Aortic regurgitation: a common complication after surgery for hypertrophic obstructive cardiomyopathy. Sasson, Z., Prieur, T., Skrobik, Y., Fulop, J.C., Williams, W.G., Henderson, M.A., Gresser, C., Wigle, E.D., Rakowski, H. J. Am. Coll. Cardiol. (1989) [Pubmed]
  2. Cerebral blood flow velocity alterations during obstructive sleep apnea syndrome. Siebler, M., Daffertshofer, M., Hennerici, M., Freund, H.J. Neurology (1990) [Pubmed]
  3. Transcranial Doppler assessment of cerebral perfusion reserve in patients with carotid occlusive disease and no evidence of cerebral infarction. Chimowitz, M.I., Furlan, A.J., Jones, S.C., Sila, C.A., Lorig, R.L., Paranandi, L., Beck, G.J. Neurology (1993) [Pubmed]
  4. Rheumatoid and psoriatic knee synovitis: clinical, grey scale, and power Doppler ultrasound assessment of the response to etanercept. Fiocco, U., Ferro, F., Vezzù, M., Cozzi, L., Checchetto, C., Sfriso, P., Botsios, C., Ciprian, L., Armellin, G., Nardacchione, R., Piccoli, A., Todesco, S., Rubaltelli, L. Ann. Rheum. Dis. (2005) [Pubmed]
  5. Intraoperative ultrasound: determination of the presence and extent of vena caval tumor thrombus. Harris, D.D., Ruckle, H.C., Gaskill, D.M., Wang, Y., Hadley, H.R. Urology (1994) [Pubmed]
  6. High resolution ultrasonography and pulsed wave Doppler for detection of corporovenous incompetence in erectile dysfunction. Vickers, M.A., Benson, C.B., Richie, J.P. J. Urol. (1990) [Pubmed]
  7. Evaluation of total cerebral blood flow volume in cerebral atrophy. Albayrak, R., Yaman, M., Uslan, I., Degirmenci, B., Acar, M., Haktanir, A. Neurosci. Lett. (2006) [Pubmed]
  8. Venous gas bubbles: production by transient, deep isobaric counterdiffusion of helium against nitrogen. D'Aoust, B.G., Smith, K.H., Swanson, H.T., White, R., Harvey, C.A., Hunter, W.L., Neuman, T.S., Goad, R.F. Science (1977) [Pubmed]
  9. Testosterone induces dilation of canine coronary conductance and resistance arteries in vivo. Chou, T.M., Sudhir, K., Hutchison, S.J., Ko, E., Amidon, T.M., Collins, P., Chatterjee, K. Circulation (1996) [Pubmed]
  10. Effect of selective angiotensin II receptor antagonism and angiotensin converting enzyme inhibition on the coronary vasculature in vivo. Intravascular two-dimensional and Doppler ultrasound studies. Sudhir, K., MacGregor, J.S., Gupta, M., Barbant, S.D., Redberg, R., Yock, P.G., Chatterjee, K. Circulation (1993) [Pubmed]
  11. In vivo molecular imaging of met tyrosine kinase growth factor receptor activity in normal organs and breast tumors. Shaharabany, M., Abramovitch, R., Kushnir, T., Tsarfaty, G., Ravid-Megido, M., Horev, J., Ron, R., Itzchak, Y., Tsarfaty, I. Cancer Res. (2001) [Pubmed]
  12. Outcome of aneurysmal subarachnoid hemorrhage in a hospital population: a prospective study including early operation, intravenous nimodipine, and transcranial Doppler ultrasound. Seiler, R.W., Reulen, H.J., Huber, P., Grolimund, P., Ebeling, U., Steiger, H.J. Neurosurgery (1988) [Pubmed]
  13. The noninvasive diagnosis and management of a uterine arteriovenous malformation. Flynn, M.K., Levine, D. Obstetrics and gynecology. (1996) [Pubmed]
  14. Randomised study assessing the effect of phenytoin and magnesium sulphate on maternal cerebral circulation in eclampsia using transcranial Doppler ultrasound. Naidu, S., Payne, A.J., Moodley, J., Hoffmann, M., Gouws, E. British journal of obstetrics and gynaecology. (1996) [Pubmed]
  15. Resveratrol suppresses angiogenesis in gliomas: evaluation by color Doppler ultrasound. Chen, J.C., Chen, Y., Lin, J.H., Wu, J.M., Tseng, S.H. Anticancer Res. (2006) [Pubmed]
  16. Effect of verapamil on portal and splanchnic hemodynamics in patients with advanced posthepatitic cirrhosis using duplex Doppler ultrasound. Dinç, H., Kapicioğlu, S., Cihanyurdu, N., Can, G., Unal, M., Topkaya, L., Gümele, H.R. European journal of radiology. (1996) [Pubmed]
  17. Corticotropin-releasing hormone-induced vasodilatation in the human fetal-placental circulation: involvement of the nitric oxide-cyclic guanosine 3',5'-monophosphate-mediated pathway. Clifton, V.L., Read, M.A., Leitch, I.M., Giles, W.B., Boura, A.L., Robinson, P.J., Smith, R. J. Clin. Endocrinol. Metab. (1995) [Pubmed]
  18. The second trimester Doppler ultrasound examination is the best predictor of late pregnancy outcome in systemic lupus erythematosus and/or the antiphospholipid syndrome. Le Thi Huong, D., Wechsler, B., Vauthier-Brouzes, D., Duhaut, P., Costedoat, N., Andreu, M.R., Lefebvre, G., Piette, J.C. Rheumatology (Oxford, England) (2006) [Pubmed]
  19. The effect of lumbar epidural anesthesia on maternal middle cerebral artery blood flow in normal pregnancy: a prospective, randomized, double-blind comparison study. Fong, J., Mack, P.F., Gurewitsch, E.D. Am. J. Obstet. Gynecol. (1998) [Pubmed]
  20. Noninvasive assessment of the maternal cerebral circulation by transcranial Doppler ultrasound during angiotensin II infusion. Kyle, P.M., de Swiet, M., Buckley, D., Serra Serra, V., Redman, C.W. British journal of obstetrics and gynaecology. (1993) [Pubmed]
  21. Doppler ultrasound measurement of cardiac output in patients with physiologic pacemakers. Effects of left ventricular function and retrograde ventriculoatrial conduction. Stewart, W.J., Dicola, V.C., Harthorne, J.W., Gillam, L.D., Weyman, A.E. Am. J. Cardiol. (1984) [Pubmed]
  22. Large coronary arteries in humans are responsive to changing blood flow: an endothelium-dependent mechanism that fails in patients with atherosclerosis. Nabel, E.G., Selwyn, A.P., Ganz, P. J. Am. Coll. Cardiol. (1990) [Pubmed]
  23. Effects of adrenomedullin on ocular hemodynamic parameters in the choroid and the ophthalmic artery. Dorner, G.T., Garhöfer, G., Huemer, K.H., Golestani, E., Zawinka, C., Schmetterer, L., Wolzt, M. Invest. Ophthalmol. Vis. Sci. (2003) [Pubmed]
  24. Baroreflex control of stroke volume in man: an effect mediated by the vagus. Casadei, B., Meyer, T.E., Coats, A.J., Conway, J., Sleight, P. J. Physiol. (Lond.) (1992) [Pubmed]
  25. 'Malignant' middle cerebral artery territory infarction: clinical course and prognostic signs. Hacke, W., Schwab, S., Horn, M., Spranger, M., De Georgia, M., von Kummer, R. Arch. Neurol. (1996) [Pubmed]
  26. Splanchnic blood flow in man: evidence for mediation via a beta-adrenergic mechanism. Braatvedt, G.D., Flynn, M.D., Stanners, A., Halliwell, M., Corrall, R.J. Clin. Sci. (1993) [Pubmed]
  27. Assessment of coronary conductance and resistance vessel reactivity in response to nitroglycerin, ergonovine and adenosine: in vivo studies with simultaneous intravascular two-dimensional and Doppler ultrasound. Sudhir, K., MacGregor, J.S., Barbant, S.D., Foster, E., Fitzgerald, P.J., Chatterjee, K., Yock, P.G. J. Am. Coll. Cardiol. (1993) [Pubmed]
  28. Assessment of cerebral vasomotor reactivity by transcranial Doppler ultrasound and breath-holding. A comparison with acetazolamide as vasodilatory stimulus. Müller, M., Voges, M., Piepgras, U., Schimrigk, K. Stroke (1995) [Pubmed]
  29. Lisinopril improves aortic compliance and renal flow. Comparison with nifedipine. Shimamoto, H., Shimamoto, Y. Hypertension (1995) [Pubmed]
  30. Studies of acute ischemic stroke with proton magnetic resonance spectroscopy: relation between time from onset, neurological deficit, metabolite abnormalities in the infarct, blood flow, and clinical outcome. Wardlaw, J.M., Marshall, I., Wild, J., Dennis, M.S., Cannon, J., Lewis, S.C. Stroke (1998) [Pubmed]
  31. Color Doppler ultrasound measurements after topical and retrobulbar epinephrine in primate eyes. Netland, P.A., Siegner, S.W., Harris, A. Invest. Ophthalmol. Vis. Sci. (1997) [Pubmed]
  32. Relationship between cytochrome P-450 induction by rifampicin, hepatic volume and portal blood flow in man. Reichel, C., Block, W., Skodra, T., Träber, F., Schiedermaier, P., Spengler, U., Nuber, R., Schild, H.H., Sauerbruch, T. European journal of gastroenterology & hepatology. (1997) [Pubmed]
  33. AKT participates in endothelial dysfunction in hypertension. Iaccarino, G., Ciccarelli, M., Sorriento, D., Cipolletta, E., Cerullo, V., Iovino, G.L., Paudice, A., Elia, A., Santulli, G., Campanile, A., Arcucci, O., Pastore, L., Salvatore, F., Condorelli, G., Trimarco, B. Circulation (2004) [Pubmed]
  34. Evidence against a putative role for glucagon as a physiological splanchnic vasodilator in man. Braatvedt, G.D., Stanners, A., Newrick, P.G., Halliwell, M., Corrall, R.J. Clin. Sci. (1993) [Pubmed]
  35. Fasting and post-prandial splanchnic blood flow is reduced by a somatostatin analogue (octreotide) in man. Cooper, A.M., Braatvedt, G.D., Qamar, M.I., Brown, H., Thomas, D.M., Halliwell, M., Read, A.E., Corrall, R.J. Clin. Sci. (1991) [Pubmed]
  36. Maternal serum activin A, inhibin A, and follistatin in pregnancies with appropriately grown and small-for-gestational-age fetuses classified by umbilical artery Doppler ultrasound. Bobrow, C.S., Holmes, R.P., Muttukrishna, S., Mohan, A., Groome, N., Murphy, D.J., Soothill, P.W. Am. J. Obstet. Gynecol. (2002) [Pubmed]
  37. Usefulness of pulsed Doppler ultrasound in detection of angiographically evident recurrence of hepatocellular carcinoma after arterial embolization treatment. Mochida, S., Hayashi, S., Ogata, I., Masaki, N., Nagoshi, S., Tomiya, T., Ohno, A., Takatsuki, K., Ohta, Y., Yamada, S. Hepatology (1991) [Pubmed]
  38. Intraoperative transesophageal echocardiography of atrioventricular septal defect. Roberson, D.A., Muhiudeen, I.A., Silverman, N.H., Turley, K., Haas, G.S., Cahalan, M.K. J. Am. Coll. Cardiol. (1991) [Pubmed]
  39. Peritoneal ventilation in rabbits: augmentation of gas exchange with cisapride. Barr, J., Lushkov, G., Strauss, S., Gurevitch, S., Lahat, E., Bistritzer, T., Klin, B., Eshel, G. Thorax (1996) [Pubmed]
  40. Transthoracic needle biopsy of thoracic tumours by a colour Doppler ultrasound puncture guiding device. Wang, H.C., Yu, C.J., Chang, D.B., Yuan, A., Lee, Y.C., Yang, P.C., Kuo, S.H., Luh, K.T. Thorax (1995) [Pubmed]
  41. Vasomotor responses to decreased venous return: effects of cardiac deafferentation in humans. Weisbrod, C.J., Arnolda, L.F., McKitrick, D.J., O'Driscoll, G., Potter, K., Green, D.J. J. Physiol. (Lond.) (2004) [Pubmed]
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