Disease relevance of Anodonta

• Sensitivity of Adenylyl Cyclase Signaling System of the Mollusk Anodonta cygnea Ganglions to Serotonin and Adrenergic Agonists [1].

High impact information on Anodonta

• For the first time, insulinlike growth factor I (IGF-I), like insulin (Pertseva et al., Comp Biochem Physiol 112: 689-695, 1995), was shown to exercise a GTP-dependent stimulating action on adenylyl cyclase (AC; EC 4.6.1.1.) activity in the muscle tissues (membrane fraction) of mammal (rat) and mollusc (Anodonta cygnea) [2].
• Human relaxin 2 (10(-12)-10(-8) M) has been shown to cause a dose-dependent activating effect on AC in the human myometrium (+370%), in rat skeletal muscles (+117%) and the smooth foot muscles of the bivalve mollusc Anodonta cygnea (+73%) [3].
• In the sarcolemma fraction of foot muscles of a fresh-water bivalve mollusc, Anodonta cygnea, a direct inhibitory, rather than stimulatory, effect of the beta-adrenergic agonist isoproterenol, at micromolar concentration, on cAMP level and adenylate cyclase activity, was revealed [4].
• Beta-agonist-induced inhibitory-guanine-nucleotide-binding regulatory protein coupling to adenylate cyclase in mollusc Anodonta cygnea foot muscle sarcolemma [4].
• How is O2 consumption maintained independent of ambient oxygen in mussel Anodonta cygnea [5]?

Biological context of Anodonta

• Distinct glutathione-dependent enzyme activities and a verapamil-sensitive binding of xenobiotics in a fresh-water mussel Anodonta cygnea [6].
• Cadmium kinetics in freshwater clams. III. Effects of zinc on uptake and distribution of cadmium in Anodonta cygnea [7].
• To verify the role of hemolymph during vitellogenesis of mussels, the saltwater mussel Mytilus edulis and the freshwater mussel Anodonta cygnea were exposed to 17beta-estradiol (E2) and wastewater treatment plant effluents, known for their estrogenic potential [8].

Anatomical context of Anodonta

• In vitro-uptake and localization of 3H-5 hydroxytryptophan and 3H-dihydroxyphenylalanine have been investigated by means of light microscopic autoradiography in the central nervous system of the freshwater mussel, Anodonta cygnea L [9].
• Molecular mechanisms of the regulatory effect of biogenic amines on the functional activity of the adenylate cyclase signal system in nerve ganglia of the mollusk Anodonta cygnea [10].
• Distribution of amino acids and serotonin in subcellular fractions or nervous tissue from Anodonta cygnea [11].

Associations of Anodonta with chemical compounds

• Avoidance responses to aluminium in the freshwater bivalve Anodonta cygnea [12].
• Pentachlorophenol accumulation in the freshwater mussels Anodonta anatina and Pseudanodonta complanata, and some physiological consequences of laboratory maintenance [13].
• Cadmium kinetics in freshwater clams. IV. Histochemical localization of cadmium in Anodonta cygnea and Anodonta anatina, exposed to cadmium chloride [14].
• Bioindicator methods were used to study the effects of the pyrethroid insecticide deltamethrin on the filtering behavior of the freshwater mussel Anodonta cygnea L in the laboratory, during short-term (30 min) and long-term (1 week) exposure [15].
• In this paper, glycosaminoglycans from the body of the large freshwater mollusc bivalve Anodonta anodonta were recovered at about 0.6 mg/g of dry tissue, composed of chondroitin sulfate (approximately 38%), nonsulfated chondroitin (about 21%), and heparin (41%) [16].

Gene context of Anodonta

• Pleiotropic Action of Insulin-like Peptides of Mollusk, Anodonta cygnea [17].
• Freshwater mussels (Anodonta anatina L.) were exposed to [14C]pentachlorophenol (PCP) and [14C]3,4,5-trichloroguaiacol (CG-3) under laboratory conditions [18].
• 1. HCO3(-)-stimulated ATPase activity was demonstrated in mantle tissue of the freshwater clam, Anodonta cataracta [19].
• 1. Microsomal preparations from the gills of the freshwater mussel anodonta cygnea cellensis show Mg2+ -dependent Na+ - or K+ -stimulated ATPase activity, which is not inhibited by ouabain [20].
• Involvement of the adenylyl cyclase signaling system in the mechanism of action of the mammalian insulin and epidermal growth factor as well as of insulin-like peptide isolated from the bivalve mollusk Anodonta cygnea has been studied [21].

References