Disease relevance of Churg-Strauss Syndrome

• METHODS: We analyzed the incidence of 5/7 Id in patients with ANCA-associated vasculitides (WG, microscopic polyangiitis, Churg-Strauss syndrome), in disease controls (systemic lupus erythematosus patients), and in healthy donors [1].
• OBJECTIVE: To estimate the prevalences of polyarteritis nodosa (PAN), microscopic polyangiitis (MPA), Wegener's granulomatosis (WG), and Churg-Strauss syndrome (CSS) [2].
• Mononeuritis in Churg-Strauss syndrome in Asians responding to intravenous cyclophosphamide [3].
• BACKGROUND: Some leukotriene receptor antagonists, such as zafirlukast and montelukast, have been associated with systemic eosinophilia, with interest focused on Churg-Strauss syndrome (CSS) [4].
• ANCA-positive Churg-Strauss syndrome with renal failure [5].

High impact information on Churg-Strauss Syndrome

• Zafirlukast and Churg-Strauss syndrome [6].
• Churg-Strauss syndrome during pregnancy after steroid withdrawal [7].
• Macrolide-induced Churg-Strauss syndrome in patient with atopy [8].
• CONCLUSION: Detection of ANCA by the combination of IIF and antigen-specific assays for proteinase 3 and myeloperoxidase in diseases that mimic systemic vasculitides is highly specific for WG, microscopic polyangiitis, and Churg-Strauss syndrome [9].
• OBJECTIVE: To investigate cytokine production patterns of T cell lines (TCL) from patients with Churg-Strauss syndrome (CSS) [10].

Chemical compound and disease context of Churg-Strauss Syndrome

• Churg-Strauss syndrome after corticosteroid withdrawal in an asthmatic patient treated with pranlukast [11].
• Churg-Strauss syndrome with montelukast [12].
• Cyclosporin in the treatment of Churg-Strauss syndrome [13].
• Cocaine-induced Churg-Strauss vasculitis [14].
• Churg-Strauss syndrome associated with fluticasone therapy [15].

Biological context of Churg-Strauss Syndrome

• OBJECTIVE: To examine the operating characteristics of the American College of Rheumatology (ACR) classification criteria for Churg-Strauss syndrome (CSS) and Wegener's granulomatosis (WG), and to develop and validate improved criteria for distinguishing CSS from WG [16].

Gene context of Churg-Strauss Syndrome

• RESULTS: Primary necrotizing small vessel vasculitides such as Wegener's granulomatosis, Churg-Strauss syndrome, microscopic polyangiitis, and renal-limited rapidly progressive necrotizing glomerulonephritis target either the serine protease proteinase 3 or myeloperoxidase in azurophilic granules [17].
• Involvement of soluble CD95 in Churg-Strauss syndrome [18].
• Treatment of refractory Churg-Strauss-Syndrome (CSS) by TNF-alpha blockade [19].
• A patient with allergic granulomatous angiitis accompanied by increases in serum interleukin-2 receptor (IL-2R) and interferon-alpha (IFN-alpha) levels is reported [20].
• Serum interleukin-2 receptor and interferon-alpha levels in a patient with allergic granulomatous angiitis (Churg-Strauss) [20].

Analytical, diagnostic and therapeutic context of Churg-Strauss Syndrome

• OBJECTIVE: To study the long term effectiveness of intravenous immunoglobulin and plasmapheresis associated with prednisone and cyclophosphamide in Churg-Strauss syndrome [21].
• RESULTS: In four patients (Sjögren's syndrome, Churg-Strauss vasculitis, SLE, and vaccination induced vasculitis) the neuropathy resolved after IVIg treatment [22].
• OBJECTIVE: To examine the safety and efficacy of methotrexate (MTX) plus low-dose prednisolone for induction of remission in non life- or organ-threatening courses and for remission maintenance in Churg-Strauss syndrome (CSS) [23].
• Perfusion lung scanning with Tc-99m MAA in the assessment of Churg-Strauss syndrome [24].
• After a review of medical literature, we found one case of congestive cardiomyopathy and no cases of endobronchial granulomas observed by bronchoscopy associated with Churg-Strauss syndrome [25].

References