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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Remission Induction

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Disease relevance of Remission Induction


Psychiatry related information on Remission Induction


High impact information on Remission Induction


Chemical compound and disease context of Remission Induction


Biological context of Remission Induction


Anatomical context of Remission Induction


Associations of Remission Induction with chemical compounds


Gene context of Remission Induction

  • After 45 days of remission induction therapy on Eastern Cooperative Oncology Group protocol E2491, CRABP-II mRNA was modestly increased from day 0 values in patients treated with either RA (median increase, 0.41) or chemotherapy (median increase, 0.56), and there was no significant difference between the two treatment groups (P = 0.91) [32].
  • We therefore measured BAX and PKCalpha protein levels in peripheral blood mononuclear cell lysates from 165 newly diagnosed AML patients and correlated the expression of these proteins with BCL2 expression, patient survival, and remission induction success [33].
  • CONCLUSIONS: Antagonizing CD154-CD40 interactions with ch5D12 is a promising therapeutic approach for remission induction in Crohn's disease [34].
  • Use of standardized flow cytometric determinants of multidrug resistance to analyse response to remission induction chemotherapy in patients with acute myeloblastic leukaemia [35].
  • These results may help to explain the differing adverse effects of pgp (on remission induction) and FLT3 ITDs (on relapse) in AML [36].

Analytical, diagnostic and therapeutic context of Remission Induction


  1. Myelodysplastic syndrome in an infant: induction of remission by cyclosporin. Porta, F., Facchetti, F., Tettoni, K., Laffranchi, M.G., Arrighini, A., Ugazio, A.G. Lancet (1998) [Pubmed]
  2. Immunological detection of minimal residual disease in children with acute lymphoblastic leukaemia. Coustan-Smith, E., Behm, F.G., Sanchez, J., Boyett, J.M., Hancock, M.L., Raimondi, S.C., Rubnitz, J.E., Rivera, G.K., Sandlund, J.T., Pui, C.H., Campana, D. Lancet (1998) [Pubmed]
  3. Cis-diamminedichloroplatinum, vinblastine, and bleomycin combination chemotherapy in disseminated testicular cancer. Einhorn, L.H., Donohue, J. Ann. Intern. Med. (1977) [Pubmed]
  4. All-trans retinoic acid/As2O3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia. Shen, Z.X., Shi, Z.Z., Fang, J., Gu, B.W., Li, J.M., Zhu, Y.M., Shi, J.Y., Zheng, P.Z., Yan, H., Liu, Y.F., Chen, Y., Shen, Y., Wu, W., Tang, W., Waxman, S., De Thé, H., Wang, Z.Y., Chen, S.J., Chen, Z. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  5. Moderate dose methotrexate, vincristine, asparaginase, and dexamethasone for treatment of adult acute lymphocytic leukemia. Esterhay, R.J., Wiernik, P.H., Grove, W.R., Markus, S.D., Wesley, M.N. Blood (1982) [Pubmed]
  6. Use of acyclovir for prophylaxis of herpes infections in severely immunocompromised patients. Prentice, H.G. J. Antimicrob. Chemother. (1983) [Pubmed]
  7. Four-agent induction and intensive asparaginase therapy for treatment of childhood acute lymphoblastic leukemia. Clavell, L.A., Gelber, R.D., Cohen, H.J., Hitchcock-Bryan, S., Cassady, J.R., Tarbell, N.J., Blattner, S.R., Tantravahi, R., Leavitt, P., Sallan, S.E. N. Engl. J. Med. (1986) [Pubmed]
  8. Comparison of combination therapy with single-drug therapy in early rheumatoid arthritis: a randomised trial. FIN-RACo trial group. Möttönen, T., Hannonen, P., Leirisalo-Repo, M., Nissilä, M., Kautiainen, H., Korpela, M., Laasonen, L., Julkunen, H., Luukkainen, R., Vuori, K., Paimela, L., Blåfield, H., Hakala, M., Ilva, K., Yli-Kerttula, U., Puolakka, K., Järvinen, P., Hakola, M., Piirainen, H., Ahonen, J., Pälvimäki, I., Forsberg, S., Koota, K., Friman, C. Lancet (1999) [Pubmed]
  9. Remission induction with adenosine-deaminase inhibitor 2'-deoxycoformycin in Thy-lymphoblastic leukaemia. Prentice, H.G., Smyth, J.F., Ganeshaguru, K., Wonke, B., Bradstock, K.F., Janossy, G., Goldstone, A.H., Hoffbrand, A.V. Lancet (1980) [Pubmed]
  10. Induction of remission in hepatocellular carcinoma with doxorubicin. Johnson, P.J., Williams, R., Thomas, H., Sherlock, S., Murray-Lyon, I.M. Lancet (1978) [Pubmed]
  11. High remission-induction rate in acute myeloid leukaemia. Gale, R.P., Cline, M.J. Lancet (1977) [Pubmed]
  12. Treatment of acute nonlymphocytic leukemia: use of anthracycline-cytosine arabinoside induction therapy and comparison of two maintenance regimens. Preisler, H.D., Rustum, Y., Henderson, E.S., Bjornsson, S., Creaven, P.J., Higby, D.J., Freeman, A., Gailani, S., Naeher, C. Blood (1979) [Pubmed]
  13. Results of consecutive trials for children newly diagnosed with acute myeloid leukemia from the Australian and New Zealand Children's Cancer Study Group. O'Brien, T.A., Russell, S.J., Vowels, M.R., Oswald, C.M., Tiedemann, K., Shaw, P.J., Lockwood, L., Teague, L., Rice, M., Marshall, G.M. Blood (2002) [Pubmed]
  14. Double induction strategy for acute myeloid leukemia: the effect of high-dose cytarabine with mitoxantrone instead of standard-dose cytarabine with daunorubicin and 6-thioguanine: a randomized trial by the German AML Cooperative Group. Büchner, T., Hiddemann, W., Wörmann, B., Löffler, H., Gassmann, W., Haferlach, T., Fonatsch, C., Haase, D., Schoch, C., Hossfeld, D., Lengfelder, E., Aul, C., Heyll, A., Maschmeyer, G., Ludwig, W.D., Sauerland, M.C., Heinecke, A. Blood (1999) [Pubmed]
  15. Combination intrathecal therapy for meningeal leukemia: two versus three drugs. Sullivan, M.P., Moon, T.E., Trueworthy, R., Vietti, T.J., Humphrey, G.B., Komp, D. Blood (1977) [Pubmed]
  16. Therapy of untreated acute myeloid leukemia in the elderly: remission-induction using a non-cytarabine-containing regimen of mitoxantrone plus etoposide. Bow, E.J., Sutherland, J.A., Kilpatrick, M.G., Williams, G.J., Clinch, J.J., Shore, T.B., Rubinger, M., Schacter, B.A. J. Clin. Oncol. (1996) [Pubmed]
  17. Improved outcome for children with acute lymphoblastic leukemia: results of Total Therapy Study XIIIB at St Jude Children's Research Hospital. Pui, C.H., Sandlund, J.T., Pei, D., Campana, D., Rivera, G.K., Ribeiro, R.C., Rubnitz, J.E., Razzouk, B.I., Howard, S.C., Hudson, M.M., Cheng, C., Kun, L.E., Raimondi, S.C., Behm, F.G., Downing, J.R., Relling, M.V., Evans, W.E. Blood (2004) [Pubmed]
  18. Relationship of the growth of leukemic cells in vitro to the outcome of therapy for acute nonlymphocytic leukemia. Preisler, H.D., Azarnia, N., Marinello, M. Cancer Res. (1984) [Pubmed]
  19. A characteristic pattern of leukemic cell differentiation without cytoreduction during remission induction in acute promyelocytic leukemia. Kantarjian, H.M., Keating, M.J., McCredie, K.B., Beran, M., Walters, R., Dalton, W.T., Hittleman, W., Freireich, E.J. J. Clin. Oncol. (1985) [Pubmed]
  20. Ciprofloxacin for selective decontamination of the alimentary tract in patients with acute leukemia during remission induction treatment: the effect on fecal flora. Rozenberg-Arska, M., Dekker, A.W., Verhoef, J. J. Infect. Dis. (1985) [Pubmed]
  21. Increase of erythropoiesis and thrombopoiesis, and induction of remission by granulocyte colony-stimulating factor (G-CSF) in a patient with hypoplastic leukemia. Yanagisawa, K., Yano, A., Takada, K., Yasukawa, M., Fujita, S. Leukemia (1994) [Pubmed]
  22. A randomized controlled trial of filgrastim during remission induction and consolidation chemotherapy for adults with acute lymphoblastic leukemia: CALGB study 9111. Larson, R.A., Dodge, R.K., Linker, C.A., Stone, R.M., Powell, B.L., Lee, E.J., Schulman, P., Davey, F.R., Frankel, S.R., Bloomfield, C.D., George, S.L., Schiffer, C.A. Blood (1998) [Pubmed]
  23. Cisplatin-refractory, HER2/neu-expressing germ-cell cancer: induction of remission by the monoclonal antibody Trastuzumab. Kollmannsberger, C., Pressler, H., Mayer, F., Kanz, L., Bokemeyer, C. Ann. Oncol. (1999) [Pubmed]
  24. Bone marrow necrosis and thrombotic complications in childhood acute lymphoblastic leukemia. Eguiguren, J.M., Pui, C.H. Med. Pediatr. Oncol. (1992) [Pubmed]
  25. The effect of short-course high-dose methylprednisolone on peripheral blood lymphocyte subsets in children with acute leukemia during remission induction treatment. Tunç, B., Oner, A.F., Hiçsönmez, G. Leuk. Res. (2003) [Pubmed]
  26. Fungal infections in patients with neutropenia: challenges in prophylaxis and treatment. Herbrecht, R., Neuville, S., Letscher-Bru, V., Natarajan-Amé, S., Lortholary, O. Drugs & aging. (2000) [Pubmed]
  27. Wegener granulomatosis: an analysis of 158 patients. Hoffman, G.S., Kerr, G.S., Leavitt, R.Y., Hallahan, C.W., Lebovics, R.S., Travis, W.D., Rottem, M., Fauci, A.S. Ann. Intern. Med. (1992) [Pubmed]
  28. Prevention of infection by trimethoprim-sulfamethoxazole plus amphotericin B in patients with acute nonlymphocytic leukaemia. Dekker, A.W., Rozenberg-Arska, M., Sixma, J.J., Verhoef, J. Ann. Intern. Med. (1981) [Pubmed]
  29. Infection prophylaxis in acute leukemia: a comparison of ciprofloxacin with trimethoprim-sulfamethoxazole and colistin. Dekker, A.W., Rozenberg-Arska, M., Verhoef, J. Ann. Intern. Med. (1987) [Pubmed]
  30. Direct relationship between remission duration in acute myeloid leukemia and cell cycle kinetics: a leukemia intergroup study. Raza, A., Preisler, H.D., Day, R., Yasin, Z., White, M., Lykins, J., Kukla, C., Barcos, M., Bennett, J., Browman, G. Blood (1990) [Pubmed]
  31. Intermittent combination chemotherapy with adriamycin for childhood acute lymphoblastic leukemia: clinical results. Sallan, S.E., Cammita, B.M., Cassady, J.R., Nathan, D.G., Frei, E. Blood (1978) [Pubmed]
  32. Constitutive expression of cellular retinoic acid binding protein II and lack of correlation with sensitivity to all-trans retinoic acid in acute promyelocytic leukemia cells. Zhou, D.C., Hallam, S.J., Lee, S.J., Klein, R.S., Wiernik, P.H., Tallman, M.S., Gallagher, R.E. Cancer Res. (1998) [Pubmed]
  33. BAX and PKCalpha modulate the prognostic impact of BCL2 expression in acute myelogenous leukemia. Kornblau, S.M., Vu, H.T., Ruvolo, P., Estrov, Z., O'Brien, S., Cortes, J., Kantarjian, H., Andreeff, M., May, W.S. Clin. Cancer Res. (2000) [Pubmed]
  34. Safety and tolerability of antagonist anti-human CD40 Mab ch5D12 in patients with moderate to severe Crohn's disease. Kasran, A., Boon, L., Wortel, C.H., Hogezand, R.A., Schreiber, S., Goldin, E., Boer, M., Geboes, K., Rutgeerts, P., Ceuppens, J.L. Aliment. Pharmacol. Ther. (2005) [Pubmed]
  35. Use of standardized flow cytometric determinants of multidrug resistance to analyse response to remission induction chemotherapy in patients with acute myeloblastic leukaemia. Pallis, M., Turzanski, J., Harrison, G., Wheatley, K., Langabeer, S., Burnett, A.K., Russell, N.H. Br. J. Haematol. (1999) [Pubmed]
  36. Resistance to spontaneous apoptosis in acute myeloid leukaemia blasts is associated with p-glycoprotein expression and function, but not with the presence of FLT3 internal tandem duplications. Pallis, M., Turzanski, J., Grundy, M., Seedhouse, C., Russell, N. Br. J. Haematol. (2003) [Pubmed]
  37. Association of PML-RAR alpha fusion mRNA type with pretreatment hematologic characteristics but not treatment outcome in acute promyelocytic leukemia: an intergroup molecular study. Gallagher, R.E., Willman, C.L., Slack, J.L., Andersen, J.W., Li, Y.P., Viswanatha, D., Bloomfield, C.D., Appelbaum, F.R., Schiffer, C.A., Tallman, M.S., Wiernik, P.H. Blood (1997) [Pubmed]
  38. Teniposide plus cytarabine improves outcome in childhood acute lymphoblastic leukemia presenting with a leukocyte count greater than or equal to 100 x 10(9)/L. Dahl, G.V., Rivera, G.K., Look, A.T., Hustu, H.O., Kalwinsky, D.K., Abromowitch, M., Mirro, J., Ochs, J., Murphy, S.B., Dodge, R.K. J. Clin. Oncol. (1987) [Pubmed]
  39. Very early treatment with infliximab in addition to methotrexate in early, poor-prognosis rheumatoid arthritis reduces magnetic resonance imaging evidence of synovitis and damage, with sustained benefit after infliximab withdrawal: results from a twelve-month randomized, double-blind, placebo-controlled trial. Quinn, M.A., Conaghan, P.G., O'Connor, P.J., Karim, Z., Greenstein, A., Brown, A., Brown, C., Fraser, A., Jarret, S., Emery, P. Arthritis Rheum. (2005) [Pubmed]
  40. Chronic immunologic thrombocytopenic purpura: results of cyclophosphamide therapy before splenectomy. Srichaijul, T., Boonpucknavig, S., Archararit, N., Chaisiri-pumkeeree, W. Arch. Intern. Med. (1980) [Pubmed]
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