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MeSH Review

Reflex, Babinski

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Disease relevance of Reflex, Babinski


Psychiatry related information on Reflex, Babinski


High impact information on Reflex, Babinski

  • Autosomal dominant pure spastic peraplegia (ADPSP) is a degenerative disorder of the central motor system clinically characterized by slowly progressive and unremitting spasticity of the legs, hyperreflexia and Babinski's sign [7].
  • Babinski's sign in Medieval, Renaissance, and Baroque art [8].
  • Pupillary light reaction (6.4 days), Babinski reflex (12.4 days), and Glasgow Coma Score (9.6 days) were the most valuable clinical findings [9].
  • These findings suggest that there is a gradual release or organisation of the reflex flexor synergy of which the Babinski sign is a modified part [10].
  • Other components include tendon hyper-reflexia, clonus, the clasp-knife phenomenon, flexor and extensor spasms, a Babinski sign, and spastic dystonia [11].

Chemical compound and disease context of Reflex, Babinski

  • Spasticity, Babinski reflexes, clonus, strength, and coactivation of antagonist muscles during voluntary movement were decreased shortly after baclofen administration began [12].
  • The disappearance of the "spasticity," extensor plantar responses, and extrapyramidal signs, following levodopa therapy, confirmed the diagnosis of doparesponsive dystonia in these patients [13].
  • A striatal toe has been defined as an apparent extensor plantar response, without fanning of the toes, in the absence of any other signs suggesting dysfunction of the cortico-spinal tract [14].

Anatomical context of Reflex, Babinski


Gene context of Reflex, Babinski


Analytical, diagnostic and therapeutic context of Reflex, Babinski


  1. Deficit of in vivo mitochondrial ATP production in patients with Friedreich ataxia. Lodi, R., Cooper, J.M., Bradley, J.L., Manners, D., Styles, P., Taylor, D.J., Schapira, A.H. Proc. Natl. Acad. Sci. U.S.A. (1999) [Pubmed]
  2. Case of the month: April 1997--a 32 year old man with mental status changes and a severe occipital headache. Lieberman, A.P., Grossman, R.I., Lavi, E. Brain Pathol. (1998) [Pubmed]
  3. HTLV-I-associated myelopathy in a Californian: diagnosis by reactivity to a viral recombinant antigen. Honig, L.S., Lipka, J.J., Young, K.Y., Weiss, J.H., Foung, S.K. Neurology (1991) [Pubmed]
  4. Sulfasalazine-associated encephalopathy in a patient with Crohn's disease. Schoonjans, R., Mast, A., Van Den Abeele, G., Dewilde, D., Achten, E., Van Maele, V., Pauwels, W. Am. J. Gastroenterol. (1993) [Pubmed]
  5. Neurologic changes during awakening from anesthesia. Rosenberg, H., Clofine, R., Bialik, O. Anesthesiology (1981) [Pubmed]
  6. X-linked spastic paraplegia. Ulkü, A., Karasoy, H., Karatepe, A., Gökçay, F. Acta neurologica Scandinavica. (1991) [Pubmed]
  7. CAG repeat expansion in autosomal dominant pure spastic paraplegia linked to chromosome 2p21-p24. Nielsen, J.E., Koefoed, P., Abell, K., Hasholt, L., Eiberg, H., Fenger, K., Niebuhr, E., Sørensen, S.A. Hum. Mol. Genet. (1997) [Pubmed]
  8. Babinski's sign in Medieval, Renaissance, and Baroque art. Massey, E.W. Arch. Neurol. (1990) [Pubmed]
  9. Early recovery after closed traumatic head injury: somatosensory evoked potentials and clinical findings. Claassen, J., Hansen, H.C. Crit. Care Med. (2001) [Pubmed]
  10. Temporal course of the threshold and size of the receptive field of the Babinski sign. Estañol, B. J. Neurol. Neurosurg. Psychiatr. (1983) [Pubmed]
  11. The pathophysiology of spasticity. Sheean, G. Eur. J. Neurol. (2002) [Pubmed]
  12. Multidimensional assessment of motor function in a child with cerebral palsy following intrathecal administration of baclofen. Almeida, G.L., Campbell, S.K., Girolami, G.L., Penn, R.D., Corcos, D.M. Physical therapy. (1997) [Pubmed]
  13. Dopa-responsive dystonia simulating cerebral palsy. Nygaard, T.G., Waran, S.P., Levine, R.A., Naini, A.B., Chutorian, A.M. Pediatric neurology. (1994) [Pubmed]
  14. The frequency and significance of 'striatal toe' in parkinsonism. Winkler, A.S., Reuter, I., Harwood, G., Chaudhuri, K.R. Parkinsonism Relat. Disord. (2002) [Pubmed]
  15. Constant involvement of the Betz cells and pyramidal tract in multiple system atrophy: a clinicopathological study of seven autopsy cases. Tsuchiya, K., Ozawa, E., Haga, C., Watabiki, S., Ikeda, M., Sano, M., Ooe, K., Taki, K., Ikeda, K. Acta Neuropathol. (2000) [Pubmed]
  16. Constant and severe involvement of Betz cells in corticobasal degeneration is not consistent with pyramidal signs: a clinicopathological study of ten autopsy cases. Tsuchiya, K., Murayama, S., Mitani, K., Oda, T., Arima, K., Mimura, M., Nagura, H., Haga, C., Akiyama, H., Yamanouchi, H., Mizusawa, H. Acta Neuropathol. (2005) [Pubmed]
  17. Bobble-head doll syndrome: some atypical features with a new lesion and review of the literature. Bhattacharyya, K.B., Senapati, A., Basu, S., Bhattacharya, S., Ghosh, S. Acta neurologica Scandinavica. (2003) [Pubmed]
  18. Acute spinal epidural hematoma and systemic mastocytosis. Arias, M., Villalba, C., Requena, I., Vázquez-Veiga, H., Sesar, A., Pereiro, I. Spine. (2004) [Pubmed]
  19. Late-onset adrenoleukodystrophy associated with long-standing psychiatric symptoms. Garside, S., Rosebush, P.I., Levinson, A.J., Mazurek, M.F. The Journal of clinical psychiatry. (1999) [Pubmed]
  20. Babinski response: stimulus and effector. Gijn, J.V. J. Neurol. Neurosurg. Psychiatr. (1975) [Pubmed]
  21. Plantar response during infancy. Katiyar, G.P., Sen, S., Agarwal, K.N. Acta neurologica Scandinavica. (1976) [Pubmed]
  22. Atlantoaxial subluxation and syringomyelia in Down syndrome: report of one case. Hou, J.W., Lin, Y.J., Wang, P.J., Wang, T.R. Zhonghua Minguo xiao er ke yi xue hui za zhi [Journal]. Zhonghua Minguo xiao er ke yi xue hui (1992) [Pubmed]
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