The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Chemical Compound Review

IGE     2-(propan-2- yloxymethyl)oxirane

Synonyms: NSC-4127, CCRIS 2631, LS-109, NCI-C56439, ACMC-209jbe, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of IGE

 

High impact information on IGE

  • Antigen-mediated IGE receptor aggregation and signaling: a window on cell surface structure and dynamics [6].
  • METHODS: Of the cohort of the Dutch Study of Epilepsy in Childhood (n = 466), all children younger than 6 years with a diagnosis of idiopathic (IGE) or cryptogenic (CGE) generalized epilepsy either at intake (n = 108) and/or after 2 years of follow-up (n = 102) were included [1].
  • We describe the case of a young man with IGE-mediated hypersensitivity to milk, casein, and lactoglobulin, who went into respiratory crisis every time he milked his sheep [7].
  • Enhancement of IGE-induced mediator release from rat peritoneal mast cells by serum-treated zymosan [8].
  • Recent studies in common IGE showed evidence for linkage on chromosome 18q12 at the D18S474 locus [9].
 

Biological context of IGE

 

Anatomical context of IGE

 

Associations of IGE with other chemical compounds

  • Technetium-99m hexamethylpropylene amine oxime (HMPAO) brain single-photon emission tomography (SPET) scans were acquired for each subject using a single-headed rotating gamma camera (IGE CamStar XR/T) [15].
 

Gene context of IGE

  • EPM 1 was therefore investigated as a candidate locus in the set of families segregating for IGE and JME which do not show linkage to markers on chromosome 6p [11].
  • China fir (Cunninghamia lanceolata var. lanceolata) and maple (Acer sp.) wood were etherified with isopropyl glycidyl ether and the decay resistance and light stability of the modified wood were assessed [16].
  • During that time a planned changeover took place in the Neuroradiological Department, with the replacement of a ten-year-old EMI 1010 head scanner by an IGE 8800 [17].
  • CP/MAS (13)C NMR and FT-IR analyses indicated that new ether bonds containing isopropyl groups formed after reacting wood with isopropyl glycidyl ether [16].
 

Analytical, diagnostic and therapeutic context of IGE

References

  1. Nonsymptomatic generalized epilepsy in children younger than six years: excellent prognosis, but classification should be reconsidered after follow-up: the Dutch Study of Epilepsy in Childhood. Middeldorp, C.M., Geerts, A.T., Brouwer, O.F., Peters, A.C., Stroink, H., van Donselaar, C.A., Arts, W.F. Epilepsia (2002) [Pubmed]
  2. Eye closure sensitivity and epileptic syndromes: A retrospective study of 26 adult cases. Sevgi, E.B., Saygi, S., Ciger, A. Seizure : the journal of the British Epilepsy Association (2007) [Pubmed]
  3. A case of cold urticaria due to a serum factor belonging to the IGE class. Akiyama, T., Ushijima, N., Anan, S., Takahashi, I., Yoshida, H. J. Dermatol. (1981) [Pubmed]
  4. Evaluation of total IgE in diverse allergosis. Comparative study with other techniques. Part I. Subirá, M.L., Sampedro, J., Oehling, A., Martín-Gil, D. Allergologia et immunopathologia. (1975) [Pubmed]
  5. B-cell chronic lymphocytic leukemia associated with high serum IGE levels and pruriginous skin lesions: successful therapy with IFN-alpha 2b after failure on IFN-gamma. Neuber, K., Berg-Drewniock, B., Volkenandt, M., Neumaier, M., Zeller, W., Gross, G., Ring, J. Dermatology (Basel) (1996) [Pubmed]
  6. Antigen-mediated IGE receptor aggregation and signaling: a window on cell surface structure and dynamics. Holowka, D., Baird, B. Annual review of biophysics and biomolecular structure. (1996) [Pubmed]
  7. Hypersensitivity reactions from inhalation of milk proteins. Vargiu, A., Vargiu, G., Locci, F., Del Giacco, S., Del Giacco, G.S. Allergy (1994) [Pubmed]
  8. Enhancement of IGE-induced mediator release from rat peritoneal mast cells by serum-treated zymosan. Otani, I., Conrad, D.H., Ruddy, S. Cell. Immunol. (1984) [Pubmed]
  9. Association between D18S474 locus on chromosome 18q12 and idiopathic generalized epilepsy. Lucarelli, P., Rizzo, R., Gagliano, A., Palmarino, M., Volzone, A., Arpino, C., Curatolo, P. Brain Dev. (2007) [Pubmed]
  10. Is Anisakis simplex responsible for chronic urticaria? López-Sáez, M.P., Zubeldia, J.M., Caloto, M., Olalde, S., Pelta, R., Rubio, M., Baeza, M.L. Allergy and asthma proceedings : the official journal of regional and state allergy societies. (2003) [Pubmed]
  11. Linkage analysis of idiopathic generalised epilepsy in families of probands with Juvenile Myoclonic Epilepsy and marker loci in the region of EPM 1 on chromosome 21 q: Unverricht-Lundborg disease and JME are not allelic variants. Rees, M., Curtis, D., Parker, K., Sundqvist, A., Baralle, D., Bespalova, I.N., Burmeister, M., Chung, E., Gardiner, R.M., Whitehouse, W.P. Neuropediatrics. (1994) [Pubmed]
  12. Gonadotropin and cAMP modulation of IGE binding protein production in ovarian granulosa cells. Grimes, R.W., Samaras, S.E., Barber, J.A., Shimasaki, S., Ling, N., Hammond, J.M. Am. J. Physiol. (1992) [Pubmed]
  13. Effect of aerobic conditioning on cardiovascular response to isometric exercise. Morgan, B.J., Brammell, H.L., Sable, D.L., Morton, M.L., Horwitz, L.D. Journal of applied physiology: respiratory, environmental and exercise physiology. (1982) [Pubmed]
  14. Cord blood IGE versus family history as atopic predictors in the newborn. Rivas, M.A., Boné, J., Rituerto, B., Alonso, J.P., Franco, Y., Guallar, A., Baldellou, A. Acta Paediatr. (1994) [Pubmed]
  15. A comparison of (99m)Tc-HMPAO SPET changes in dementia with Lewy bodies and Alzheimer's disease using statistical parametric mapping. Colloby, S.J., Fenwick, J.D., Williams, E.D., Paling, S.M., Lobotesis, K., Ballard, C., McKeith, I., O'Brien, J.T. Eur. J. Nucl. Med. Mol. Imaging (2002) [Pubmed]
  16. Modification of wood with isopropyl glycidyl ether and its effects on decay resistance and light stability. Chang, H.T., Chang, S.T. Bioresour. Technol. (2006) [Pubmed]
  17. Assessment of the Meditech Euroscanner for clinical use. Thomson, J.L., Fowles, S.J., Bradshaw, J.R., Longstaff, A.J. The British journal of radiology. (1985) [Pubmed]
  18. Preseasonal intranasal immunotherapy with nebulized short ragweed extract. Welsh, P.W., Zimmermann, E.M., Yunginger, J.W., Kern, E.B., Gleich, G.J. J. Allergy Clin. Immunol. (1981) [Pubmed]
  19. Typical childhood absence seizures are associated with thalamic activation. Labate, A., Briellmann, R.S., Abbott, D.F., Waites, A.B., Jackson, G.D. Epileptic disorders : international epilepsy journal with videotape. (2005) [Pubmed]
  20. High resolution SPECT using divergent geometry. Webb, S., Broderick, M., Flower, M.A. The British journal of radiology. (1985) [Pubmed]
 
WikiGenes - Universities