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Chemical Compound Review

Camphoquinone     1,7,7-trimethylbicyclo[2.2. 1]heptane-2,3...

Synonyms: Campherquinone, Camphorquinone, NSC-285, SureCN15201, zlchem 1202, ...
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Disease relevance of Camphoquinone

  • Aqueous styrenated gelatin solution premixed with AdLacZ, adenovirus encoding beta-galactosidase cDNA, and carboxylated camphorquinone (CQ) as a photoinitiator was irradiated with visible light to form a styrenated gelatin gel [1].

High impact information on Camphoquinone


Biological context of Camphoquinone


Anatomical context of Camphoquinone


Associations of Camphoquinone with other chemical compounds


Gene context of Camphoquinone

  • These multifunctional, viscous liquid copolymers (molecular weights; approximately 2 x 10(3) to 7 x 10(3) g/mol) were converted to crosslinked solids by visible-light irradiation in the presence of camphorquinone as an initiator [18].
  • METHODS: The efficiency of two LED and one QTH lamps were tested comparing their performances with the photoinitiators camphorquinone (CQ); phenylpropanedione (PPD); monoacylphosphine oxide (Lucirin TPO); and bisacylphosphine oxide (Irgacure 819) [19].
  • The main identified leachables were: iodobenzene (DPICls-diphenyliodonium chloride degradation product), camphorquinone (photo-initiator), tert-butyl-p-hydroxyanisole (inhibitor), 4-(dimethylamino)ethyl benzoate (co-initiator), ethylene glycol dimethacrylate (monomer) [20].
  • Camphorquinone with VL irradiation increased the radical production, whereas 9F with VL irradiation increased ROS production, as well as effecting changes in the DPPC phase-transition properties [21].
  • The experimental resin, which was prepared by mixing equivalent weights of Bis GMA and triethyleneglycol-dimethacrylate, was colored by one of three organic dye stuffs, and camphorquinone and dimethyl-p-toluidine were added to activate polymerization [22].

Analytical, diagnostic and therapeutic context of Camphoquinone

  • The experiment revealed that the depth of cure test does not and the Knoop hardness test does discriminate between LCUs, used for the polymerization of composites containing photoinitiators in addition to camphorquinone [23].
  • At low CQ concentrations, the DC measured by a Fourier Transform Infrared (FTIR) spectrometer increased rapidly with increasing concentration of DMAEMA and reached a plateau [24].
  • Active sensitization to camphoroquinone and double active sensitization to acrylics with long-lasting patch test reactions [25].
  • METHODS: Complexation of CQ and 4E with MCD was studied by thin layer chromatography [26].


  1. Novel therapeutic strategy for prevention of malignant tumor recurrence after surgery: Local delivery and prolonged release of adenovirus immobilized in photocured, tissue-adhesive gelatinous matrix. Okino, H., Manabe, T., Tanaka, M., Matsuda, T. Journal of biomedical materials research. Part A. (2003) [Pubmed]
  2. Quenched phosphorescence as a detection method in capillary electrophoretic chiral separations. Monitoring the stereoselective biodegradation of camphorquinone by yeast. García-Ruiz, C., Siderius, M., Ariese, F., Gooijer, C. Anal. Chem. (2004) [Pubmed]
  3. Shear bond strength of experimental methacrylated beta-cyclodextrin-based formulations. Hussain, L.A., Dickens, S.H., Bowen, R.L. Biomaterials (2005) [Pubmed]
  4. The effect of antioxidants on oxidative DNA damage induced by visible-light-irradiated camphorquinone/N,N-dimethyl-p-toluidine. Winter, K., Pagoria, D., Geurtsen, W. Biomaterials (2005) [Pubmed]
  5. Shrinkage strain-rates of dental resin-monomer and composite systems. Atai, M., Watts, D.C., Atai, Z. Biomaterials (2005) [Pubmed]
  6. Effects of sub-toxic concentrations of camphorquinone on cell lipid metabolism. Datar, R.A., Rueggeberg, F.A., Caughman, G.B., Wataha, J.C., Lewis, J.B., Schuster, G.S. Journal of biomaterials science. Polymer edition. (2005) [Pubmed]
  7. Color change in light-cured resins exposed to daylight. Burrow, M.F., Makinson, O.F. Quintessence international. (1991) [Pubmed]
  8. Argon laser initiated resin photopolymerization for the filling of root canals in human teeth. Potts, T.V., Petrou, A. Lasers in surgery and medicine. (1991) [Pubmed]
  9. Laser photopolymerization of dental materials with potential endodontic applications. Potts, T.V., Petrou, A. Journal of endodontics. (1990) [Pubmed]
  10. ROS formation and glutathione levels in human oral fibroblasts exposed to TEGDMA and camphorquinone. Engelmann, J., Volk, J., Leyhausen, G., Geurtsen, W. Journal of biomedical materials research. Part B, Applied biomaterials. (2005) [Pubmed]
  11. Cytotoxicity of photosensitizers camphorquinone and 9-fluorenone with visible light irradiation on a human submandibular-duct cell line in vitro. Atsumi, T., Murata, J., Kamiyanagi, I., Fujisawa, S., Ueha, T. Arch. Oral Biol. (1998) [Pubmed]
  12. Camphoroquinone reduction: another reaction catalyzed by rat liver cytosol 3 alpha-hydroxysteroid dehydrogenase. Boutin, J.A. Biochim. Biophys. Acta (1986) [Pubmed]
  13. Synthesis and photopolymerization of N,N'-dimethyl,-N,N'-di(methacryloxy ethyl)-1,6-hexanediamine as a polymerizable amine coinitiator for dental restorations. Nie, J., Bowman, C.N. Biomaterials (2002) [Pubmed]
  14. In situ hydrogelation of photocurable gelatin and drug release. Okino, H., Nakayama, Y., Tanaka, M., Matsuda, T. J. Biomed. Mater. Res. (2002) [Pubmed]
  15. The effect of N-acetyl-l-cysteine and ascorbic acid on visible-light-irradiated camphorquinone/N,N-dimethyl-p-toluidine-induced oxidative stress in two immortalized cell lines. Pagoria, D., Geurtsen, W. Biomaterials (2005) [Pubmed]
  16. Photocure bonding agent containing phosphoric methacrylate. Wang, T., Nikaido, T., Nakabayashi, N. Dental materials : official publication of the Academy of Dental Materials. (1991) [Pubmed]
  17. Development of a new photoinitiation system for dental light-cure composite resins. Park, Y.J., Chae, K.H., Rawls, H.R. Dental materials : official publication of the Academy of Dental Materials. (1999) [Pubmed]
  18. Liquid acrylate-endcapped biodegradable poly(epsilon-caprolactone-co-trimethylene carbonate). I. Preparation and visible light-induced photocuring characteristics. Mizutani, M., Matsuda, T. J. Biomed. Mater. Res. (2002) [Pubmed]
  19. Molar extinction coefficients and the photon absorption efficiency of dental photoinitiators and light curing units. Neumann, M.G., Miranda, W.G., Schmitt, C.C., Rueggeberg, F.A., Correa, I.C. Journal of dentistry. (2005) [Pubmed]
  20. Application of HS-SPME in the determination of potentially toxic organic compounds emitted from resin-based dental materials. Rogalewicz, R., Voelkel, A., Kownacki, I. Journal of environmental monitoring : JEM. (2006) [Pubmed]
  21. Comparative radical production and cytotoxicity induced by camphorquinone and 9-fluorenone against human pulp fibroblasts. Atsumi, T., Ishihara, M., Kadoma, Y., Tonosaki, K., Fujisawa, S. Journal of oral rehabilitation. (2004) [Pubmed]
  22. Light activated resin containing organic dyestuff. Nakazato, J., Itoh, K., Wakumoto, S. Dental materials journal. (1989) [Pubmed]
  23. Photoinitiator dependent composite depth of cure and Knoop hardness with halogen and LED light curing units. Uhl, A., Mills, R.W., Jandt, K.D. Biomaterials (2003) [Pubmed]
  24. Effect of photoinitiator on degree of conversion of unfilled light-cured resin. Yoshida, K., Greener, E.H. Journal of dentistry. (1994) [Pubmed]
  25. Active sensitization to camphoroquinone and double active sensitization to acrylics with long-lasting patch test reactions. Malanin, K. Contact Derm. (1993) [Pubmed]
  26. Effects of polymerization initiator complexation in methacrylated beta-cyclodextrin formulations. Hussain, L.A., Dickens, S.H., Bowen, R.L. Dental materials : official publication of the Academy of Dental Materials. (2004) [Pubmed]
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